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Introduction About RANTAC MPS SUSPENSION

RANTAC MPS SUSPENSION is a combination of Magaldrate and Polydimethylsiloxane which belongs to the group of medicines called Antacids and Antiflatulence. It is used to manage gastritis (inflammation of lining of stomach) and dyspepsia (indigestion), gastric and duodenal ulcers (stomach or intestinal ulcers).

RANTAC MPS SUSPENSION is also used to manage drug induced gastric irritation (injury to stomach mucosa due to adverse effects of drugs), gastro-oesophageal reflux (back flow of stomach acid into the food pipe), heart burn (burning pain in chest), stomach upset with nausea, pain, burning and flatulence.

RANTAC MPS SUSPENSION is not recommended for use in patients with kidney disease, nausea, vomiting, severe abdominal pain, acute surgical abdomen impaction and/or an intestinal obstruction. Contact your doctor before taking it.

RANTAC MPS SUSPENSION should be used in pregnancy only if clearly necessary. There is no proper information regarding the use of RANTAC MPS SUSPENSION in breastfeeding women. Therefore, consult your doctor before taking it.

RANTAC MPS SUSPENSION is not recommended for use in children under 6 years of age unless directed by physician. RANTAC MPS SUSPENSION is not recommended for use in elderly patients with bone problems or with Alzheimer’s disease. Contact your doctor if you experience any side effects after taking RANTAC MPS SUSPENSION.

Uses Of RANTAC MPS SUSPENSION

Manage:

Gastritis and dyspepsia
Gastric and Duodenal ulcers
Drug induced gastric irritation
Gastro-Oesophageal Reflux
Heart burn
Stomach upset with nausea, pain, burning and flatulence

How RANTAC MPS SUSPENSION Works

RANTAC MPS SUSPENSION is a combination of Magaldrate and Polydimethylsiloxane where Magaldrate is an Antacid works by rapidly neutralising stomach acid and reduces gastric and intestinal irritation, relieve symptoms of excessive stomach acidity in patients with indigestion, heartburn, gastroesophageal reflex disorder (GERD) or stomach or intestinal ulcers and Simethicone is an Anti-flatulence (anti-gas) medication acts in the stomach and intestines, enabling smaller gas bubbles to join together into bigger bubbles. In this way it helps in elimination of gas more easily by belching or passing flatus.

How to use RANTAC MPS SUSPENSION

Take RANTAC MPS SUSPENSION as advised by your physician. Shake well before use. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of RANTAC MPS SUSPENSION

Rare

Stop taking RANTAC MPS SUSPENSION and contact your physician immediately if you experience any of the following side effects:

allergic reactions such as rashes, hives, itching, swelling of the mouth, face, lips or tongue causing chest tightness or difficulty breathing)

Warning & Precautions

Pregnancy

Monitoring required

RANTAC MPS SUSPENSION should be used in pregnancy only if clearly necessary. Contact your doctor before taking it.

Breastfeeding

Consult your doctor

There is no proper information regarding the use of RANTAC MPS SUSPENSION in breastfeeding women. Therefore, consult your doctor before taking it.

Kidney

Contraindicated

RANTAC MPS SUSPENSION is not recommended for use in patients with kidney disease. Contact your doctor before taking it.

Allergy

Contraindicated

Do not use RANTAC MPS SUSPENSION if you are allergic to Magaldrate and Polydimethylsiloxane or to magnesium and aluminium or to other ingredients of the medicine.

Others

RANTAC MPS SUSPENSION is not recommended for use if you have:

nausea, vomiting, severe abdominal pain, acute surgical abdomen impaction and/or an intestinal obstruction
hypophosphatemia (low phosphorus levels in blood)

Before taking RANTAC MPS SUSPENSION, inform your doctor if you have:

recent massive upper Gastro intestinal bleeding

Use in paediatrics:

RANTAC MPS SUSPENSION is not recommended for use in children under 6 years of age unless directed by physician. Therefore, contact your doctor for advice before taking it.

Use in geriatrics:

RANTAC MPS SUSPENSION is not recommended for use in elderly patients with bone problems or with Alzheimer’s disease. Contact your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking RANTAC MPS SUSPENSION, inform your doctor if you are taking any of the following medicine:

citrate salts (medicines used for constipation, heart burn and calcium supplements) Ex. magnesium citrate
oral tetracyclines, methenamine (medicines used for bacterial infections)
digoxin (used for heart failure)
oral iron preparations (medicines used to manage anaemia) Ex. ferrous fumarate
anticholinergic drugs Ex. hyoscyamine (used to manage stomach cramps)
barbiturates Ex. phenobarbital (used to manage fits)
quinine (used to manage malaria)
warfarin (used to manage blood clots)
vitamins (vitamin supplements)
sucralfate, H2- receptor antagonists (medicines used for stomach and intestinal ulcers)
sodium fluoride (used for dental preparations)
ketoconazole (used to manage fungal infections)
phenytoin (used to manage fits)
phenothiazines Ex. trifluoperazine (medicines used for schizophrenia)
propranolol (used for high blood pressure and heart failure)
isoniazid (used for tuberculosis)
prednisolone (used to manage inflammation)
naproxen (used to manage pain)
levothyroxine (used for thyroid disease)

Overdosage:

If you or anyone else accidentally take too much of RANTAC MPS SUSPENSION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are dizziness, fatigue, weakness, severe nausea and vomiting, loss of appetite, drowsiness, shallow breathing or loss of consciousness. Large dose can cause obstruction.

Synopsis

Drug	:	Magaldrate, Polydimethylsiloxane
Pharmacological Category	:	Antacids and Antiflatulence
Therapeutic Indication	:	Gastritis and dyspepsia, gastric and duodenal ulcers, drug induced gastric irritation, gastro-oesophageal reflux, heart burn and stomach upset with nausea, pain, burning, and flatulence
Dosage Forms	:	Syrup

More Information

Keep RANTAC MPS SUSPENSION out of the sight and reach of children
Store RANTAC MPS SUSPENSION below 30°C

FAQs About RANTAC MPS SUSPENSION

Q: How often can I take RANTAC MPS SUSPENSION?

A: Take RANTAC MPS SUSPENSION as advised by your physician. Take 10-20 ml three or four times a day, on empty stomach or as directed by a doctor. If symptoms occur at night, then it is usually administered before retiring. However, it is more important not to eat within 2 hours of sleep as eating often promotes reflux of acid into the esophagus.

Q: How long can I use RANTAC MPS SUSPENSION?

A: Take RANTAC MPS SUSPENSION as advised by your physician. RANTAC MPS SUSPENSION can be used indefinitely if they are only taken occasionally. Do not use maximum dose of this product for more than two weeks, except under advice and supervision of a physician. However, when it is necessary several times a day, contact your doctor and he/she will prescribe some other medicines called H2 blocker or PPIs for managing your condition.

Q: Is RANTAC MPS SUSPENSION safe in pregnancy?

A: RANTAC MPS SUSPENSION should be used in pregnancy only if clearly necessary. Inform your doctor if you are pregnant or planning for pregnancy before taking this medicine.

Q: Can I use RANTAC MPS SUSPENSION in children?

A: No, RANTAC MPS SUSPENSION is generally not recommended for use in children under 6 years of age unless clearly necessary. Contact your doctor before taking this medicine.

Q: Who should avoid taking RANTAC MPS SUSPENSION?

A: RANTAC MPS SUSPENSION is not recommended for use in patients with kidney disease, elderly patients with bone problems or with Alzheimer’s disease, hypophosphatemia (low phosphorus levels in blood), nausea, vomiting, severe abdominal pain, acute surgical abdomen impaction or intestinal obstruction. Contact your doctor before taking it.

References

1. K.D. Tripathi. Drugs for peptic ulcer and G.E.R.D. Essentials of medical pharmacology. Seventh edition. 2013. Page – 655.

2. Curtis J. Ingold, Hossein Akhondi. Simethicone. NIH National Library of Medicine, National Center for Biotechnology Information. StatPearls. July 2022. [Accessed on 27th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK555997/

3. Giannini EG, Zentilin P, Dulbecco P, Iiritano E, Bilardi C, Savarino E, Mansi C, Savarino V. A comparison between sodium alginate and magaldrate anhydrous in the treatment of patients with gastroesophageal reflux symptoms. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed.gov. November 2006. [Accessed on 27th June 2022]

4. J. B. Chemicals & Pharmaceuticals Ltd. Magaldrate and Polydimethylsiloxane. [Accessed on 27th July 2022] https://medicaldialogues.in/uploads/2020/06/11/file_upload-130213.pdf

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 30 Jan 2023 | 02:48 PM(IST)

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