INTRODUCTION

PLANEP 50MG contain Eplerenone which belongs to a group of medicine called selective aldosterone blocking agents. These blocking agents works by inhibiting the action of aldosterone which controls the blood pressure and heart function. High levels of aldosterone in our body leads to heart failure. In combination with other drugs used to treat your heart failure, it is used to treat heart attack that are persistent and its mild symptoms.

It helps in preventing worsening of heart condition and reduce hospitalisations. Before taking this medicine, tell your doctor if you have ever had kidney, liver, heart disease. You may feel dizzy while taking this medicine. If you feel dizzy, do not drive or operate machinery. If you have liver or severe kidney disease, you may need more frequent testing of your blood potassium levels. Your physician may adjust the dose depending on the potassium levels in your blood.

Take this medicine as instructed by your doctor. This medicine must be taken with food or empty stomach. Swallow the tablet whole with plenty of water and do not crush or chew the medicine. Consumption of alcohol is not recommended during treatment with PLANEP 50MG. Do not take this medicine if you are allergic (hypersensitive) to Eplerenone or any other ingredients in this medicine. The most common side effects of this medicine are elevated potassium level in your blood, dizziness, headache, elevated quantity of cholesterol in your blood, insomnia, irregular heartbeat, cough and constipation.

USES OF PLANEP 50MG

• Treat heart failure
• Treat high blood pressure

HOW PLANEP 50MG WORKS

PLANEP 50MG works by inhibiting the action of aldosterone, a substance produced within the body, which controls your blood pressure and improves heart function.

DIRECTIONS FOR USE

Take PLANEP 50MG as instructed by your doctor. This medicine must be taken with food or empty stomach. Swallow the medicine whole with plenty of water and do not crush or chew the medicine.

SIDE EFFECTS OF PLANEP 50MG

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Lie down and close the eyes, Drink plenty of water and keep hydrated.

Constipation:

Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Diarrhoea:

Drink lots of fluids to avoid dehydration. Avoid taking any other medicines to treat diarrhoea without speaking to a doctor.

Nausea and vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor, if you are taking,

• medicines to treat any bacterial, fungal or viral infections
• medicines to treat depression
• potassium sparing diuretics (helps to excrete excess body fluid)
• medicines to treat high blood pressure, heart disease or kidney conditions
• lithium (usually given for manic depressive disorder, also called bipolar disorder)
• cyclosporin or tacrolimus (immunosuppressants used to prevent rejection after organ transplantation)
• ibuprofen (used to relieve pain, stiffness, and inflammation)
• prazosin or alfuzosin (used to treat high blood pressure and particular prostate
• antipsychotics medicines such as chlorpromazine or haloperidol (used to treat psychiatric disorders)
• amifostine (used during cancer chemotherapy)
• baclofen (used to treat muscle spasm)
• glucocorticoids such as hydrocortisone or prednisone (used to treat inflammation and certain skin conditions)
• tetracosactide (used for diagnosing and treating adrenal cortex disorders)
• digoxin (used to treat heart conditions)
• anti-clotting drug such as warfarin (used to treat blood clot)
• carbamazepine, phenytoin, and phenobarbital (used to treat epilepsy)

SYNOPSIS

MORE INFORMATION

Store at a room temperature and keep out of reach of children.

FAQs ABOUT PLANEP 50MG

Does PLANEP 50MG cause erectile dysfunction?

No, it does not cause erectile dysfunction. it does not have any effect on fertility in both males and females.

How PLANEP 50MG works?

It works by inhibit the action of aldosterone, a substance produced within the body, which controls your blood pressure and improves heart function.

Can aspirin be taken along with PLANEP 50MG?

When aspirin taken along with this medicine it may interfere with the working of this medicine. Both may increase the chances of rise in potassium levels in patients with kidney problems. Therefore, if both are to be used together, keep monitoring your blood pressure and potassium levels.

REFERENCES

1. KD Tripathi. Diuretics. Essentials of Medical Pharmacology. Seventh Edition,2013. Page-589.

2. Alan J Zillich 1, Barry L Carter. Eplerenone--a novel selective aldosterone blocker.NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov.Oct 2002. [Accessed 17 Nov 2020] https://pubmed.ncbi.nlm.nih.gov/12243608/

3. Accord Healthcare Limited; Electronic Medicines Compendium (EMC); [Revised on Aug 2017] [Accessed 17 Nov 2020] https://www.medicines.org.uk/emc/files/pil.7055.pdf

USEFUL DIAGNOSTIC TESTS

• Electrocardiogram (ECG)