PICON contains Pimecrolimus which belongs to the group of medicines called Immunosuppressants. It is used to treat atopic dermatitis (eczema). Eczema is an inflammatory condition of the skin characterized by red and itchy rashes. Allergies are the main common cause of eczema. Symptoms include dry skin, severe itching, redness of hands, feet, ankles, wrist and neck, etc.
PICON is not recommended for use in other skin conditions and skin affected by an active viral infection such as cold sores (herpes simplex) or chicken pox. Avoid exposure to sunlight while using PICON. This medicine is generally not recommended for use among pregnant and breastfeeding women.
The most common side effects of using PICON are feeling of warmth and burning sensation at the application site, irritation, itching, and reddening of the skin where the cream has been applied and skin infections (such as folliculitis). Consult your doctor if any of the side effect worsens.
PICON is a calcineurin inhibitor. It works by blocking calcineurin (a protein in our bodies that helps to activate our immune system). By blocking the immune response it lessens the inflammation which is caused by eczema.
Always apply PICON as directed by your physician. It is for external use only. Wash and dry your hands before applying. Apply a thin layer of PICON to the affected area and rub it gently and fully. Avoid applying this medicine around nose, eyes or mouth. Do not cover the treated areas of skin with dressings, bandages, and wraps. Also, do not bath or shower right after applying the cream as this could wash your cream off. Your doctor will decide the duration of treatment depending on severity of the condition.
Stop applying PICON and contact your doctor immediately if you experience any of the following side effects:
Itchy skin:
Avoid hot showers as hot water can irritate the skin further. Do not scratch the affected area. Use sunscreen and protective clothing when going outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area after consulting the doctor. Consult your doctor if the itching worsens.
PICON is generally not recommended for use in pregnant women. Consult your doctor before using it.
PICON is generally not recommended for use in breastfeeding women as it is not known whether it may pass through breast milk. Consult your doctor before using it.
PICON has no known effect on the ability to drive or use machines.
Avoid consumption of alcohol while applying PICON as it may cause flushing, rash, burning or itching sensation or swelling. Consult your doctor before using it.
Do not apply PICON if you are allergic to Pimecrolimus or any of the other ingredients of this medicine.
PICON is not recommended for use if you:
Before applying PICON, inform your doctor if you have:
Use in pediatrics:
PICON is generally not recommended for use in children (under 3 months of age). Consult child’s doctor for advice.
Use in geriatrics:
PICON should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before applying PICON.
A. Drug-Drug interactions:
Before applying PICON, inform your doctor if you are taking or applying any of the following medicines:
Overdosage:
If you or anyone else applied too much of PICON or accidentally swallowed the medicine, consult your doctor immediately or visit the nearby hospital.
Drug | : | Pimecrolimus |
Pharmacological Category | : | Immunosuppressant |
Therapeutic Indication | : | Atopic dermatitis (eczema) |
Dosage Forms | : | Cream, Lotion |
What is PICON used for?
PICON is used to treat atopic dermatitis (eczema) of the skin, in cases where corticosteroids cannot be used. Eczema is an inflammatory condition of the skin characterized by red and itchy rashes. Allergies are the main common cause of eczema. Symptoms include dry skin, severe itching, redness of hands, feet, ankles, wrist, and neck, etc.
Can I consume alcohol while using PICON?
Avoid consumption of alcohol while applying PICON as it may cause flushing, rash, burning or itching sensation or swelling. Consult your doctor before using it.
Is PICON safe to use in breast-feeding women?
PICON is generally not recommended for use in breastfeeding women as it is not known whether it may pass through breast milk. Consult your doctor before using it.
When to avoid using PICON?
PICON is not recommended for use if your skin is affected by an active viral infection such as cold sores (herpes simplex) or chickenpox. Also, not recommended for use in patients who are allergic to pimecrolimus.
What common side effects are seen with PICON?
The most common side effects of using PICON are feeling of warmth and burning sensation at the application site, irritation, itching and reddening of the skin where the cream has been applied and skin infections (such as folliculitis). Consult your doctor if any of the side effect worsens.
1. Matthew J. Sewell, Craig N. Burkhart, and Dean S. Morrell. Dermatological Pharmacology. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page – 1271-1296.
2. Grace K. Kim, and James Del Rosso. Uses of Pimecrolimus Cream. The Journal of Clinical and Aesthetic Dermatology. February 2013 [Accessed on 8th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579486/
3. Novartis Pharmaceuticals. Safety and Efficacy of Pimecrolimus Cream 1% in Atopic Disease Modification. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in March 2011] [Accessed on 8th June 2022] https://clinicaltrials.gov/ct2/show/NCT00124709
4. Mylan Products Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2022]. [Accessed on 8th June 2022] https://www.medicines.org.uk/emc/files/pil.4966.pdf
5. Biocon Biologics India Limited. Pimecrolimus solution 1% w/v (Picon lotion). Biocon.com. [Revised in August 2019]. [Accessed on 8th June 2022] https://www.biocon.com/docs/domestic-marketpi/immuno/PICON%20LOTION%20PI.pdf
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