INTRODUCTION

PICLIN TABLET contains Sodium picosulfate which belongs to the group of medicines called Laxatives. It is used for short term relief of functional constipation. Constipation is defined as fewer than three bowel movements a week, stools that are hard, dry, lumpy, difficult or painful to pass.

Your doctor might advise to take rich fibre diet, more fluid intake, and do regular exercise. PICLIN TABLET is not recommended for use in patients with acute liver failure, severe dehydration, ileus, gastrointestinal obstruction, gastrointestinal ulceration or perforation.

It is also not recommended if you have appendicitis, acute inflammatory bowel diseases, severe abdominal pain associated with nausea and vomiting, sudden/severe abdominal pain just before intake, undiagnosed rectal bleeding.

PICLIN TABLET should be used with caution in patients with kidney, heart disease, recent gastro-intestinal surgery, inflammatory bowel disease. Contact your doctor before taking. PICLIN TABLET is generally not recommended for use in pregnancy and breastfeeding women unless it is clearly necessary.

PICLIN TABLET is not recommended for use in children under 10 years of age. PICLIN TABLET should be used with caution in elderly patients. The most common side effects of taking PICLIN TABLET are diarrhoea, abdominal pain, cramps, or discomfort. Do consult your physician if any of the side effects worsen.

USES OF PICLIN TABLET

• Used to treat short-term relief of functional constipation

HOW PICLIN TABLET WORKS

PICLIN TABLET works by increasing the mucosa of the large intestine and rectum. Which in turn increases its motility (movement), accumulation of water, hence softening the stool and stimulating defecation (emptying of bowel).

DIRECTIONS FOR USE

Take PICLIN TABLET as advised by your doctor. Swallow the whole medicine with glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of medicine depending upon your age, body weight and disease condition.       

SIDE EFFECTS OF PICLIN TABLET

HOW TO MANAGE SIDE EFFECTS

Stomach pain:

Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. Contact your doctor if the stomach pain doesn’t improve.

Diarrhoea:

Drink plenty of water or fruit juices to keep yourself hydrated. Don’t take any medicine on your own for treating diarrhoea. Contact your doctor if diarrhoea worsen.

WARNING & PRECAUTIONS

PREGNANCY

PICLIN TABLET is generally not recommended for use in pregnancy or women planning to have a baby unless it is considered clearly necessary by the doctor. Contact your doctor before taking it.

BREASTFEEDING

PICLIN TABLET is generally not recommended for use in breastfeeding women unless it is considered clearly necessary by the doctor. Contact your doctor before taking PICLIN TABLET.

DRIVING AND USING MACHINES

PICLIN TABLET has no or negligible influence on ability to drive and use machines.

KIDNEY

PICLIN TABLET should be used with caution in patients with kidney disease. Contact your doctor before taking PICLIN TABLET.

LIVER

PICLIN TABLET is not recommended for use in patients with and acute liver failure. Contact your doctor before taking.

ALLERGY

Do not take PICLIN TABLET if you are allergic to Sodium picosulfate or any other ingredients of this medicine.

HEART DISEASE

PICLIN TABLET should be used with caution in patients with heart disease. Contact your doctor before taking.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking PICLIN TABLET, inform your doctor if you are taking any of the following medicine:

• diuretics (medicines used to increase urine output) Ex. amiloride
• corticosteroids (medicines used to treat inflammatory conditions) Ex. cortisone
• lithium (used to treat mental illness)
• cardiac glycosides (used to treat heart disorders) Ex. digoxin
• anti-epileptics (medicines used to treat fits) Ex. carbamazepine
• contraceptives (medicines used to prevent pregnancy) Ex. progestin
• anti-diabetics (medicines used to treat diabetes) Ex. metformin, glipizide
• NSAIDs (medicines used to treat pain) Ex. diclofenac, ibuprofen
• tricyclic antidepressants (Ex. amoxapine), selective serotonin re-uptake inhibitors (medicines used to treat depression, anxiety and panic disorders) Ex. fluoxetine
• antipsychotic drugs (medicines used to treat psychoses) Ex. clozapine, haloperidol
• carbamazepine (to treat epilepsy)
• antibiotics (used to treat infections) Ex. amoxicillin

Overdosage:

If you or anyone else accidentally take too much of PICLIN TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are diarrhoea, abdominal cramps and a clinically significant loss of potassium and other electrolytes.

SYNOPSIS

MORE INFORMATION

• Keep PICLIN TABLET out of sight and reach of children
• Store PICLIN TABLET at room temperature

FAQs ABOUT PICLIN TABLET

Q: What is PICLIN TABLET used for?

A: PICLIN TABLET is used for short term relief of functional constipation in adults and children above 10 years of age. Contact your doctor for more information before taking it.

Q: Does PICLIN TABLET help with weight loss?

A: Stimulant laxatives, including PICLIN TABLET do not help with weight loss. These medicines do not reduce the absorption of calories or nutrients. They may cause watery stools (diarrhoea), abdominal cramps and dehydration. Dehydration may seem like weight loss.

Q: What does constipation mean and why does it happen?

A: Constipation is a bowel disorder that occurs due to slowing down of the muscle actions in the large intestine. It may be caused due to a sudden change of diet, a less fibrous diet, loss of muscle tone in elderly people, pregnancy, certain medicines (morphine or codeine), prolonged bedtime and lack of exercise. The symptoms of constipation include bloating, discomfort or sometimes headache.

Q: What are the natural ways to treat constipation?

A: Constipation may be relieved by certain lifestyle and diet modifications such as: Eat a balanced diet including fresh fruit and vegetables, drink enough water so that you do not become dehydrated and exercise to stay fit.

Q: How does PICLIN TABLET help in relieving constipation?

A: PICLIN TABLET works by increasing the mucosa of the large intestine and rectum. Which in turn increases its motility (movement), accumulation of water, hence softening the stool and stimulating defecation (emptying of bowel).

REFERENCES

1. K.D. Tripathi. Drugs for Constipation and Diarrhoea. Essentials of Medical Pharmacology. 6th Edition. 2013. Page- 674.

2. Hyun Gun Kim, Kyu Chan Huh, Hoon Sup Koo, Seong-Eun Kim, Jin-Oh Kim, Tae Il Kim, Hyun-Soo Kim, Seung-Jae Myung, Dong Il Park, Jeong Eun Shin, Dong-Hoon Yang, Suck-Ho Lee, Ji Sung Lee, Chang Kyun Lee, Dong Kyung Chang, Young-Eun Joo, Jae Myung Cha, Sung Pil Hong, and Hyo Jong Kim. Sodium Picosulfate with Magnesium Citrate (SPMC) Plus Laxative Is a Good Alternative to Conventional Large Volume Polyethylene Glycol in Bowel Preparation: A Multicenter Randomized Single-Blinded Trial. NIH. National Library of Medicine, National Centre for Biotechnology Information. Pubmed Central. July 2015. [Accessed on 17th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477993/

3. Sung Sil Park, Sung Chan Park, Dong-Eun Lee, Dong Woon Lee, Kiho Yu, Hyoung-Chul Park, Chang Won Hong, Dae Kyung Sohn, Kyung Su Han, Bun Kim, Byung Chang Kim, and Jae Hwan Oh. The risk of surgical site infection of oral sulfate tablet versus sodium picosulfate for bowel preparation in colorectal cancer surgery: a randomized clinical trial. NIH. National Library of Medicine, National Centre for Biotechnology Information. Pubmed Central. August 2022. [Accessed on 17th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365640/

4. Ferring Ireland Ltd. Health Products Regulatory Authority (HPRA). [Revised in September 2012] [Accessed on 17th August 2022] http://www.hpra.ie/img/uploaded/swedocuments/LicenseSPC_PA1009-024-002_24052013132038.pdf

AUTHOR DETAILS

Written By Dr. Shruthi M R, BDS
Last updated on 10 Jan 2023 | 04:49 PM(IST)