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PEXOPRAM 0.5MG TABLET contains Pramipexole which belongs to the group of medicines called Dopamine agonists. It is used to treat signs and symptoms of idiopathic Parkinson’s disease.
It is also prescribed to treat conditions such as Restless Legs Syndrome.
A disorder of the central nervous system that affects movement, often including tremors. Nerve cell damage in the brain causes dopamine levels to drop, leading to the symptoms of Parkinson's.
PEXOPRAM 0.5MG TABLET should not be given in patients with kidney diseases and psychosis. PEXOPRAM 0.5MG TABLET is not recommended for use in pregnancy and breastfeeding.
This medicine is strictly for use in adults and should not be used in children and adolescents under 18 years of age.
The common side effects of taking PEXOPRAM 0.5MG TABLET include sleepiness, dizziness, dyskinesia, nausea, hallucinations (seeing, hearing or feeling things that are not present), abnormal dreams, confusion, behavioural symptoms (Impulse control and compulsions), headache, double or blurred vision, low blood pressure, constipation, vomiting, swelling of body usually in the legs, decreased weight and appetite. Consult your doctor for advice if any of the above side effects worsen.
PEXOPRAM 0.5MG TABLET is a dopamine agonist which binds to a set of dopamine receptors in the brain. It relieves Parkinsonism by stimulating dopamine receptors present in the striatum (part of the brain that is responsible for cognition, planning, decision-making, motivation, reinforcement, and reward perception).
Take PEXOPRAM 0.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop takingPEXOPRAM 0.5MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Take PEXOPRAM 0.5MG TABLET during or after meals to minimise effects. Consult your doctor for advice.
Eat fibre rich food, drink plenty of fluids to avoid constipation. Consult your doctor for advice.
Use of PEXOPRAM 0.5MG TABLET is not recommended in pregnant women. Contact your doctor before taking.
PEXOPRAM 0.5MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.
Use of PEXOPRAM 0.5MG TABLET can cause sleepiness, drowsiness, hallucinations and sudden onset of sleep. Hence, it is not recommended to drive or use machines after taking this medicine.
Avoid alcohol consumption while taking PEXOPRAM 0.5MG TABLET as it may increase the risk of sleepiness.
PEXOPRAM 0.5MG TABLET should be used with caution in patients with kidneys disease. Contact your doctor before taking.
PEXOPRAM 0.5MG TABLET should be used with caution in patients with liver diseases. Contact your doctor before taking.
Do not take PEXOPRAM 0.5MG TABLET if you are allergic to Pramipexole or to other ingredients of the medicine.
PEXOPRAM 0.5MG TABLET should be used with caution in patients with existing pulmonary diseases. Contact your doctor before taking.
PEXOPRAM 0.5MG TABLET should be used with caution in patients with severe heart and blood vessel disease. Contact your doctor before taking.
PEXOPRAM 0.5MG TABLET is not recommended for use if you have:
Use in pediatrics:
Use of PEXOPRAM 0.5MG TABLET is not advisable in children and adolescents under 18 years of age. Contact your doctor before taking.
Use in geriatrics:
PEXOPRAM 0.5MG TABLET should be used with caution in elderly patients over 65 years of age. Contact your doctor to get the correct dose.
A. Drug-Drug Interactions:
Before taking PEXOPRAM 0.5MG TABLET, inform your doctor if you are taking any of the following medicine:
If you miss a dose of PEXOPRAM 0.5MG TABLET, do not take double dose. If you have accidentally taken too much of this medicine, contact your doctor or nearest hospital immediately for advice. Symptoms of overdosage are vomiting, nausea, agitation, low blood pressure, hallucination, restlessness, confusion.
|Pharmacological Category||:||Dopamine agonists|
|Therapeutic Indication||:||Idiopathic Parkinson’s disease|
What is the most important information I should know about PEXOPRAM 0.5MG TABLET?
PEXOPRAM 0.5MG TABLET may cause you to fall asleep while you are doing daily activities such as driving, talking with other people, watching TV, or eating. Do not drive a car, operate a machine, or do anything that needs you to be alert until you know how PEXOPRAM 0.5MG TABLET affects you. Tell your doctor if this happens.
When is PEXOPRAM 0.5MG TABLET used?
PEXOPRAM 0.5MG TABLET is used to treat Parkinson’s Disease and Restless Legs Syndrome. Contact your doctor before taking.
Who should not take PEXOPRAM 0.5MG TABLET?
Do not take PEXOPRAM 0.5MG TABLET if you are allergic to Pramipexole or its constituents.
What should I tell my doctor before taking PEXOPRAM 0.5MG TABLET?
Tell your doctor about all of your medical conditions including kidney problems, liver and heart problems or any other medical conditions.
How should I take PEXOPRAM 0.5MG TABLET?
Take PEXOPRAM 0.5MG TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
What should I do if I miss a dose of PEXOPRAM 0.5MG TABLET?
If you missed a dose, do not double the dose. Skip the missed dose and take your next dose at regular interval. Be sure to tell your doctor right away if you stop taking PEXOPRAM 0.5MG TABLET for any reason. Do not start taking this medicine again before speaking with your doctor.
What are the possible side effects of taking PEXOPRAM 0.5MG TABLET?
PEXOPRAM 0.5MG TABLET can cause side effects such ad dizziness, nausea, falling asleep during normal daily activities, hallucinations, low blood pressure, fainting, or sweating. Contact your physician if any of the symptoms worsen.
1. KD Tripathi. Drugs acting on Central Nervous System. Page-430 Essentials of Medical Pharmacology.
2. Boehringer Ingelheim Pharmaceuticals, Inc. [Revised in July 2021] [Accessed on 12th July 2022] https://docs.boehringeringelheim.com/Prescribing%20Information/PIs/.pdf
3. McDermott Laboratories Ltd. Pramipexole Dihydrochloride. [Revised in June 2021] [Accessed on 12th July 2022] https://www.medicines.org.uk/emc/files/pil.10327.pdf
4. Pramipexole Dihydrochloride. National Library of Medicine. [Revised in August 2021] [Accessed on 13th July 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=00699692-532a-68fd-8a51-3770a81b2208
Written By Dr. Janet.C, Pharm.D
Last updated on 18 Nov 2022 | 10:17 AM(IST)
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