PANIMUN BIORAL contains Cyclosporin which belongs to the group of medicines called immunosuppressive agents. Immunosuppressive agents are the drugs that suppress or reduces the strength of body’s immune system. It is used to prevent graft rejection in patients who have had an organ transplant, bone marrow and stem cell transplantation.
It can also be used to treat various autoimmune disease like severe rheumatoid arthritis, nephrotic syndrome (kidney disease), eye problems (endogenous uveitis, including Behçet's uveitis) and skin diseases (atopic dermatitis, or eczema and psoriasis). Cyclosporin blocks the development of cells which attack the affected transplanted tissue and suppress abnormal immune function thus preventing the rejection of transplanted organs.
Limit your exposure to sunlight and UV light by wearing protective clothing and by applying a sunscreen to prevent skin cancer. Avoid consumption of alcohol or grapefruit juice while taking this medicine. This medicine should not be given to children for any non-transplant disease, except for nephrotic syndrome. Do not take this medicine if you have any uncontrollable infection or any type of cancer. Consult your doctor for advice.
Cyclosporin works by inhibiting the production of various cytokines involved in the regulation of T-cell activation. These effects of cyclosporine on T cells and on connective tissue cells can produce a range of cytokines. These in turn promote antibody (Ab) secreting plasma cells which finally bind and inactivate the antigen.
Take this medicine as directed by your physician. Your doctor will decide the correct dose for you depending upon your condition. Avoid drinking grapefruit juice while taking this medicine.
Nausea or vomiting:
Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.
Constipation:
Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.
Diarrhea:
Drink lots of fluids to avoid dehydration. Avoid taking any medicines for diarrhoea without speaking to a doctor.
Stomach pain:
Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.
PANIMUN BIORAL should be used with caution in pregnant women. Consult your doctor before taking this medicine.
PANIMUN BIORAL should be used with caution in breast feeding women. Consult your doctor before taking this medicine.
Avoid driving or operating any machines, if your ability is affected by this medicine.
Avoid consumption of alcohol while taking this medicine, as it may increase the risk of side effects.
Do not take PANIMUN BIORAL if you are suffering from severe kidney disease. Consult your doctor for advice.
PANIMUN BIORAL should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
Do not take this medicine if you are allergic to cyclosporin.
Do not take PANIMUN BIORAL if you are suffering from uncontrollable high blood pressure. Consult your doctor for advice.
Do not take this medicine, if you have:
Talk to your doctor, if you are taking,
Drug | : | Cyclosporin |
Pharmacological Category | : | Immunosuppressive agent, Calcineurin inhibitor |
Therapeutic Indication | : | Prevents graft rejection, Treats auto immune disease |
Dosage Forms | : | Capsule, Oral suspension, Eye drops, Injection |
Store below 20-25°C and keep out of reach of children.
Can PANIMUN BIORAL cause cancer?
Yes. This medicine increases your risk of developing cancers, particularly of the skin and lymphoid system. Limit your exposure to sunlight and UV light by wearing appropriate protective clothing and applying a sunscreen with a high protection factor often while taking this medicine.
Can PANIMUN BIORAL cause unwanted hair growth?
Yes. The common side effects of this medicine is excessive growth of body and facial hair However, if you experience any unusual symptoms, contact your physician.
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