PAGE 0.5mg Tablet 10's

Diabetes Rx required
OUT OF STOCK

Best Price*  ₹ 17.60
MRP ₹22.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mfr: Orchid Chemicals & Pharmaceuticals Ltd * Country of Origin: India



INTRODUCTION

PAGE 0.5MG contains Repaglinide which belongs to a group of medicines called oral antidiabetic medicine which helps the pancreas produce more insulin and thereby lower blood sugar (glucose). It is used to control type 2 diabetes in adults along with diet and exercise. It can also be given with metformin or any other medicine for diabetes. Type 2 diabetes is a disease in which pancreas does not make enough insulin to control the sugar in the blood or where your body does not respond normally to the insulin it produces.

Repaglinide is a short-acting oral secretagogues of the meglitinide class used in the management of type 2 diabetes mellitus (non-insulin dependent diabetes mellitus). It lowers the blood glucose levels acutely by stimulating the release of insulin from the pancreas.

Always take this PAGE 0.5MG exactly as directed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems and if you are pregnant or breastfeeding. It is not suitable for children and adolescents below 18 years of age. The common side effects are diarrhoea, stomach pain and hypoglycemia.

USES OF PAGE 0.5MG

  • Used to control type 2 diabetes

HOW PAGE 0.5MG WORKS

PAGE 0.5MG lower blood glucose levels by blocking ATP-dependent potassium channels in pancreatic beta cells, which in turn, stimulates insulin secretion.

DIRECTIONS FOR USE

Always take this PAGE 0.5MG exactly as your doctor has told you. Swallow this medicine with a glass of water immediately before or up to 30 minutes before each main meal.

SIDE EFFECTS OF PAGE 0.5MG

SERIOUS

  • swelling, breathing difficulty, increased heartbeat, dizziness and sweating

COMMON

  • hypoglycaemia (low glucose level)
  • stomach pain
  • diarrhoea

HOW TO MANAGE SIDE EFFECTS

Hypoglycaemia:

Eat high sugar snack or drink, then take rest.

Stomach pain:

Place a warm water bottle on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

WARNING & PRECAUTIONS

PREGNANCY

PAGE 0.5MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor. 

BREASTFEEDING

PAGE 0.5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or handle any machines while taking this medicine, if your blood sugar is low or high.

ALCOHOL

Consumption of alcohol is not recommended during treatment with PAGE 0.5MG, since it can change the ability reduce the blood sugar.

KIDNEY

PAGE 0.5MG should be used with caution in patients with active kidney diseases. Consult your doctor for advice.

LIVER

PAGE 0.5MG is not recommended in patients with severe liver disorder or any other active liver diseases. Consult your doctor for advice.

ALLERGY

Do not take if you are allergic (hypersensitive) to Repaglinide.

OTHERS

Inform your doctor if you have or had,

  • type 1 diabetes
  • diabetic ketoacidosis
  • major surgery
  • severe illness or infection
  • are above 75 years of age

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

  • gemfibrozil (lower increased fat levels in blood)
  • monoamine oxidase inhibitors (used to treat depression)
  • beta blockers (treats high blood pressure)
  • Ace inhibitors (used to treat heart conditions)
  • aspirin
  • octreotide (used to treat cancer)
  • nonsteroidal anti-inflammatory drugs  
  • anabolic steroids and corticosteroids (used for anemia and inflammation)
  • oral contraceptives  
  • thiazides  
  • danazol (treats breast cysts, endometriosis)
  • thyroid medicines (used to treat low levels of thyroid hormones)
  • sympathomimetics (used to treat asthma)
  • clarithromycin, trimethoprim, rifampicin (used to treat infection)
  • itraconazole and ketoconazole (used to fungal infection)
  • ciclosporin (used to suppress the immune system)
  • deferasirox (used to reduce chronic iron overload)
  • clopidogrel (used to treat blood clots)
  • phenytoin, carbamazepine, phenobarbital (used to treat epilepsy)
  • St. John’s wort (herbal medicine)

SYNOPSIS

Drug :   Repaglinide
Pharmacological Category :   Antidiabetic Agent, Meglitinide Analog
Therapeutic Indication :   Diabetes mellitus, type 2
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT PAGE 0.5MG

How long does PAGE 0.5MG take to start working?

It usually starts working 30 minutes after it has been taken, the insulin levels increase causing a decrease in the blood sugar levels and lasts for 4 hours.

Can PAGE 0.5MG be taken with other antidiabetic medicine?

Yes, it can be taken with other antidiabetic medicines but take as advised by your doctor.

Can PAGE 0.5MG be taken during breastfeeding?

No. It is not recommended during breastfeeding. Consult your doctor for advice.

REFERENCES

1. KD Tripathi MD. Insulin, oral hypoglycaemic drugs and glucagon. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page - 273.

2. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page: 1257.

3. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page: 740-741.

4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page: 1206-1207.

5. Liang-Chen Wang, Fu-Sheng Fang, Yan-Ping Gong, Guang Yang and Chun-Lin Li. Characteristics of repaglinide and its mechanism of action on insulin secretion in patients with newly diagnosed type-2 diabetes mellitus. Sep 21, 2018; [Accessed on Jan 18, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160250/

6. Novo Nordisk (Denmark). Jan 29, 2001; [Revised on July 23, 2008] [Accessed on Jan 18, 2021] https://www.ema.europa.eu/en/documents/product-information/prandin-epar-product-information_en.pdf

7. Pharmathen S.A. Mylan Hungary Kft. [Accessed on Jan 18, 2021] https://mri.cts-mrp.eu/human/downloads/BE_H_0243_003_FinalPL.pdf

8. Novo Nordisk Inc. July 14, 2008. U.S. Food & Drug Administration; [Accessed on Jan 18, 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020741s035lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • Glucose - Fasting Blood
  • Glucose - Postprandial Blood
  • Glycosylated Hemoglobin

Marketer DETAILS

    Country Of Origin
    India
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