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Opox 50mg Dry Syrup 30ml
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INTRODUCTION
OPOX 50MG DRY SYRUP contains Cefpodoxime which belongs to the group of medicines called Antibiotics. It is used to treat certain infections caused by bacteria such as acute otitis media (inflammation of middle ear leading to pain and fever), tonsilitis (sore throat, difficulty swallowing and tender lymph nodes), chronic bronchitis (inflammation of the airways present in the lungs leading to cough with mucus), community acquired pneumonia (inflammation of lungs leading to congestion), gonorrhoea (sexually transmitted infection in rectum, cervix or vagina).
It is also used to treat uncomplicated skin and structure infections (rashes, swelling, redness, pain, pus and itching), acute maxillary sinusitis (inflammation around the nasal cavity leading to headache and runny nose) and cystitis (strong, persistent urge to urinate with burning sensation and blood in the urine).
OPOX 50MG DRY SYRUP should be avoided if you are allergic to cefpodoxime or to the cephalosporin group of antibiotics (such as cefuroxime, cefixime) or if you had experienced immediate or severe hypersensitivity reaction (anaphylaxis) to penicillin or other beta-lactam antibiotics (such as aztreonam).
Before taking OPOX 50MG DRY SYRUP, inform your doctor if you have or ever had colitis, liver problems and impaired kidney function. Your doctor may monitor your blood count and liver enzymes level in blood tests while taking OPOX 50MG DRY SYRUP.
OPOX 50MG DRY SYRUP is generally not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor. OPOX 50MG DRY SYRUP is not recommended for use in infants less than 2 months of age and it should be used with caution in elderly patients, especially in patients with impaired kidney function.
The most common side effects of taking OPOX 50MG DRY SYRUP are diarrhoea, nausea, abdominal pain and headache. Consult your doctor if any of the side effects worsen.
USES OF OPOX 50MG DRY SYRUP
It is used in adults and adolescents to treat the following bacterial infections:
- acute otitis media
- pharyngitis and/or tonsillitis
- community-acquired pneumonia
- acute bacterial exacerbations of chronic bronchitis
- acute, uncomplicated urethral and cervical gonorrhoea
- acute, rectal gonococcal infections in women
- uncomplicated skin and skin structure infections
- acute maxillary sinusitis
- uncomplicated urinary tract infections (cystitis)
HOW OPOX 50MG DRY SYRUP WORKS
OPOX 50MG DRY SYRUP prevents infection by stopping or preventing the bacteria from multiplying by inhibiting their cell wall formation, which is essential for the bacteria to survive as it provides protection from the environment. This kind of action that kills bacteria is useful in treating various bacterial infections.
DIRECTIONS FOR USE
Take OPOX 50MG DRY SYRUP as advised by your physician. Tap the bottle to loosen the powder. Add two-thirds of the sterile water (provided with the pack) and shake the bottle vigorously. Add more water up to the mark on the bottle and shake well before using. Allow the suspension to stand for 5 minutes.
Depending upon your age, body weight and disease condition, your doctor will decide the correct dose and duration for you.
SIDE EFFECTS OF OPOX 50MG DRY SYRUP
COMMON
- diarrhoea
- nausea, vomiting
- headache
- stomach pain
- skin rash including diaper rashes and fungal skin rashes
UNCOMMON
- fungal, bacterial and parasitic infections
- abdominal distention, malaise, fatigue, weakness, fever, chest pain, back pain, chills, generalized pain
- abscess, allergic reaction, and facial edema
- localized edema, and pain
- congestive heart failure, palpitations, changes in blood pressure
- hematoma (collection of blood outside the blood vessels)
- migraine
- vomiting, gastritis, dry mouth, flatulence, decreased appetite, constipation
- ulcers in mouth, tongue disorders, tooth disorders, increased thirst and toothache
- anaemia, dehydration and weight gain
- dizziness, insomnia, somnolence, anxiety, shakiness, nervousness, impaired concentration, confusion, nightmares, headache, syncope
- vertigo (spinning sensation)
- cough, wheezing, breathing difficulty
- skin rash with itching, hair loss, and sunburn
- taste alterations, eye irritation, taste loss and ear pain
- urinary tract infections
RARE
- changes in blood counts such as neutropenia, agranulocytosis, thrombocytopenia, lymphocytosis, leukopenia, and leucocytosis
Stop taking OPOX 50MG DRY SYRUP and contact your doctor immediately if you experience any of the following side effects:
- severe diarrhoea due to pseudomembranous colitis
- signs of allergic reaction (skin rash, joint pain, swallowing or breathing problems, swelling of your lips, face, throat or tongue)
- signs of Stevens-Johnson syndrome (blistering or bleeding of the skin around the lips, eyes, mouth, nose, genitals and fever)
- signs of toxic epidermal necrolysis (severe blistering rash where peeling of skin layer exposes the skin along with feeling of being unwell, fever, chills and muscle pain)
- signs of erythema multiforme (skin rash or skin lesions with a pink/red ring and a pale centre which may be itchy, scaly, or filled with fluid, especially on the palms or soles of your feet)
- itching, redness, burning sensation in the vagina along with white vaginal discharge
- signs of severe anemia type (infections occur more easily than usual, yellowing of the skin, eyes or mouth and feeling tired)
- seizures mainly in patients with impaired kidney function
- eyelid dermatitis (swelling and redness of eyelid followed by itchy and scaly skin)
- signs of purpuric nephritis (bruises on legs along with kidney impairment)
- early pregnancy loss, liver damage
- pulmonary infiltrate with eosinophilia (presence of eosinophils inside the lungs)
HOW TO MANAGE SIDE EFFECTS
Nausea or vomiting:
Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Headache:
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Diarrhea:
Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.
Stomach pain:
Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.
WARNING & PRECAUTIONS
PREGNANCY
OPOX 50MG DRY SYRUP is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking OPOX 50MG DRY SYRUP.
BREASTFEEDING
OPOX 50MG DRY SYRUP should be used with caution in breast-feeding women only if considered clearly necessary as small amount of this medicine is excreted in the breast milk and may cause adverse reactions in breastfed infants such as diarrhea or mucosal fungus infection. Consult your doctor before taking OPOX 50MG DRY SYRUP.
DRIVING AND USING MACHINES
Do not drive or operate any machinery if you feel dizzy after taking OPOX 50MG DRY SYRUP.
KIDNEY
OPOX 50MG DRY SYRUP should be taken with caution in patients with impaired kidney function. Consult your doctor before taking OPOX 50MG DRY SYRUP.
LIVER
OPOX 50MG DRY SYRUP should be taken with caution in patients with liver problems. Consult your doctor before taking OPOX 50MG DRY SYRUP.
ALLERGY
Do not take OPOX 50MG DRY SYRUP if you are allergic to cefpodoxime or to the cephalosporin group of antibiotics (such as cefuroxime, cefixime) or if you had experienced immediate or severe allergic reactions to penicillin or other beta-lactam antibiotics such as aztreonam.
LUNGS
OPOX 50MG DRY SYRUP is not recommended for use in patients with pneumonia or atypical pneumonia caused by certain organisms. Consult your doctor before taking OPOX 50MG DRY SYRUP.
OTHERS
Before taking OPOX 50MG DRY SYRUP, inform your doctor if you:
- have a history of gastrointestinal disease (particularly colitis)
Use in Paediatrics:
OPOX 50MG DRY SYRUP is not recommended for use in infants (less than 2 months of age) due to lack of safety and effectiveness. Therefore, consult your child’s doctor for advice.
Use in Geriatrics:
OPOX 50MG DRY SYRUP should be used with caution in elderly patients, especially in patients with impaired kidney function. Consult your doctor before taking OPOX 50MG DRY SYRUP.
INTERACTIONS
A. Drug - Drug interactions:
Before taking OPOX 50MG DRY SYRUP, inform your doctor if you are taking any of the following medicines:
- medicines used to treat stomach acid symptoms such as indigestion or stomach ulcers (Ex. aluminium hydroxide, sodium bicarbonate, magnesium hydroxide, simethicone)
- propantheline (used to treat gastric ulcers)
- medicines for treating gastric ulcers (Ex. ranitidine, cimetidine)
- medicines used to treat high blood pressure or fluid retention (Ex. spironolactone, bumetanide, torsemide)
- other medicines used to treat bacterial infections (Ex. gentamicin, streptomycin)
- probenecid (used to prevent and treat gouty arthritis)
- warfarin (used to prevent and treat blood clots)
- oestrogen (reduces the vaginal symptoms of menopause)
Overdosage:
If you or anyone else accidentally takes too much of OPOX 50MG DRY SYRUP, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of OPOX 50MG DRY SYRUP are nausea, diarrhoea, vomiting, epigastric distress and encephalopathy may occur in patients with renal insufficiency.
SYNOPSIS
| Drug | : | Cefpodoxime |
| Pharmacological Category | : | Cephalosporins |
| Therapeutic Indication | : | Various bacterial infections |
| Dosage Forms | : | Tablet, capsule, oral Suspension, syrup, oral drops, dry syrup, dry suspension, dispersible Tablet |
MORE INFORMATION
- Keep OPOX 50MG DRY SYRUP out of reach of children
- Store at room temperature
FAQs ABOUT OPOX 50MG DRY SYRUP
Is OPOX 50MG DRY SYRUP a very strong antibiotic?
OPOX 50MG DRY SYRUP works against a large spectrum of bacteria to treat tonsillitis, pneumonia, bronchitis, infection of ear, skin, urinary tract, throat, etc. It belongs to cephalosporin antibiotics, and it is very effective.
When does OPOX 50MG DRY SYRUP start showing its effect?
OPOX 50MG DRY SYRUP usually starts working in one to two hours. You should wait for improvement in symptoms as there are no external improvements seen with it. It should be taken regularly for every 12 hours for 5-14 days as advised by your doctor even if you start feeling better in the first 2 days.
Can OPOX 50MG DRY SYRUP be taken with milk?
Always take the medicine as advised by your physician. OPOX 50MG DRY SYRUP should be taken with water and not with any dairy product, juice, or calcium-based food products. In case of any discomfort while taking OPOX 50MG DRY SYRUP, inform your doctor immediately.
What are the common side effects of OPOX 50MG DRY SYRUP?
The common side effects associated with the use of OPOX 50MG DRY SYRUP are abdominal pain, diarrhoea, nausea, vomiting and headache. If any of the side effects gets worse, consult your doctor immediately.
Is the use of OPOX 50MG DRY SYRUP safe for kidneys?
GBNKEYWORD] should be used with caution in patients with impaired kidney function. Your doctor may adjust the dose depending upon kidney function and patients undergoing haemodialysis. Consult your doctor before taking OPOX 50MG DRY SYRUP.
REFERENCES
1. KD. Tripathi. Antimicrobial Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 688.
2. Fulton, Bret, and Caroline M. Perry. Cefpodoxime proxetil. Paediatric drugs. August 2012. [Accessed on 6th August 2022] https://link.springer.com/article/10.2165/00128072-200103020-00006
3. Krishan Chugh, Shruti Agrawal. Cefpodoxime: pharmacokinetics and therapeutic uses. National Library of Medicine. National center for biotechnology information. Pubmed.gov. March 2003 [Accessed on 6th August 2022] https://pubmed.ncbi.nlm.nih.gov/12785294/
4. BioBrick Pharma Ltd. Cefobil-50 (Cefpodoxime). [Accessed on 6th August 2022] https://www.biobrickpharma.com/product/cefobik-50-ww/
5. Cipla Ltd. (Cefoprox 50, 100 Oral suspension) (Cefpodoxime). [Revised in October 2018] [Accessed on 6th August 2022] https://www.ciplamed.com/content/cefoprox-tabletsdtpowder-for-oral-suspension
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Peripheral Smear Examination
- Urine test
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 30 Sep 2022 | 05:34 PM(IST)
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