INTRODUCTION

ODIMONT LC KID TABLET is a combination of Levocetirizine and Montelukast which belongs to the group of medicines called H1 receptor antagonists and Leukotriene receptor antagonists respectively. ODIMONT LC KID TABLET is indicated for the treatment and prevention of allergic rhinitis, chronic idiopathic urticaria (allergic skin reaction with red raised itchy bumps on the skin) and bronchial asthma in children aged between 6-14 years.     

Allergic rhinitis (also known as hay fever) is a heterogeneous disorder characterized by inflammation of the inner lining of the nose accompanied by nasal decongestion, repeated sneezing, wheezing, or red, watery and itchy eyes.    

It is usually caused by allergens such as pollens, dust, mould, or flakes of skin from certain animals and can occur seasonally or year-round. Bronchial asthma is a long-term medical condition in which the path of the airways becomes inflamed, narrow, and swollen. Symptoms include coughing, wheezing, and chest tightness.  

ODIMONT LC KID TABLET is contraindicated for use in children having severe kidney impairment. Consult your child’s doctor before use.     

ODIMONT LC KID TABLET may cause certain unpleasant neuropsychiatric events (such as behaviour and mood-related changes: agitation including aggressive behaviour or hostility, depression) in some children. Consult your child’s doctor immediately if your child experiences any such events.  

The most common side effects of taking ODIMONT LC KID TABLET are upper respiratory tract infection, fever, cough, inflammation of the pharynx, dryness of mouth, headache and sleepiness. Consult your child’s doctor if any of the side effects worsen.

USES OF ODIMONT LC KID TABLET

• Treats and prevents allergic rhinitis, chronic idiopathic urticaria and bronchial asthma in children aged between 6-14 years

HOW ODIMONT LC KID TABLET WORKS

ODIMONT LC KID TABLET provides relief from the symptoms of allergic rhinitis, asthma and urticaria where levocetirizine acts by blocking the actions of histamines (a substance that cause allergic reaction), at the H1 receptors present on the surface of cells and montelukast acts by blocking the action of leukotrienes D4 (an inflammatory molecule causing narrowing and swelling of the airways) in the lungs, thus causing relaxation of smooth muscle, reduction in swelling and/or inflammation of the airways and a marked decrease in the onset of allergic reactions.

DIRECTIONS FOR USE

Give ODIMONT LC KID TABLET to your child as advised by the physician

For Tablet: 

Tell your child to swallow ODIMONT LC KID TABLET with a glass of water and not to crush or chew the medicine.

For Dispersible Tablet: Disperse ODIMONT LC KID TABLET in the specified quantity of water as advised by the doctor. Tell your child to consume the mixture immediately after reconstitution.

Your child’s doctor will decide the correct dose and duration of ODIMONT LC KID TABLET for your child depending upon the child’s age, body weight and disease condition.  

SIDE EFFECTS OF ODIMONT LC KID TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Follow simple meal plan for your child while administering ODIMONT LC KID TABLET. Avoid giving foods that are oily, fried or spicy foods. Do not let your child to lie down or sleep immediately after eating. Consult the child’s doctor if the symptom does not improve.     

Diarrhoea:

Advise your child to drink plenty of water and stay hydrated. Avoid giving your child a high-fat diet or spicy foods. Try to avoid giving any medicine on your own to your child to treat diarrhoea. Consult the child’s doctor if the symptom gets worse.

Stomach pain:

Advise your child to rest and relax. Tell your child to eat and drink slowly or try to have lesser and more frequent meals. Keep a heating pad on the child’s stomach to relieve pain. Consult the child’s doctor if the symptom gets worse.

Headache:

Apply a hot or cold-water bag on your child’s head. Advise your child to take a rest in a quiet room. Massage the child’s scalp or head with mild pressure for relieving effect. Consult the child’s doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before giving ODIMONT LC KID TABLET to your child, inform to child’s doctor if your child is taking or receiving any of the following medicines: 

• gemfibrozil (used to control high blood cholesterol levels)
• phenytoin, phenobarbital (used to treat epilepsy)
• rifampicin (used to treat tuberculosis)
• ritonavir (a medicine used to treat viral infections)
• theophylline (a medicine used to treat asthma)

Overdosage:

If your child or anyone else accidentally takes too much of ODIMONT LC KID TABLET, consult your child’s doctor immediately or visit the nearby hospital. Overdosage symptoms of ODIMONT LC KID TABLET might include stomach pain, thirst, sleepiness, headache, vomiting, psychomotor hyperactivity, agitation and restlessness.

SYNOPSIS

MORE INFORMATION

• Keep ODIMONT LC KID TABLET out of reach of children
• Store ODIMONT LC KID TABLET at room temperature  

FAQs ABOUT ODIMONT LC KID TABLET

Can ODIMONT LC KID TABLET be used to treat acute asthmatic attacks in children?  

No, ODIMONT LC KID TABLET is used only to prevent an asthma attack. ODIMONT LC KID TABLET should not be used on an asthma attack that has been started already. Contact child’s doctor or go to the nearby hospital to avoid exacerbation of the attack.       

Can ODIMONT LC KID TABLET be used in infants?

No, ODIMONT LC KID TABLET is only meant to be used in children aged between 6-14 years. ODIMONT LC KID TABLET  is strictly not recommended for use in children aged below 6 years without consulting your child’s doctor.  

Can ODIMONT LC KID TABLET make my child feel sleepy?

Yes, ODIMONT LC KID TABLET can cause sleepiness or drowsiness in some children, although not everybody gets them. This is quite normal and does not need to worry about. Avoid unnecessary distractions in children and try to make them stay relaxed. Avoid taking them outdoors unnecessarily. Avoid giving them concomitant medicines that can make them drowsier like cough syrups or sedatives. If the symptom does not improve or worsens contact your child’s doctor.

Can ODIMONT LC KID TABLET make my child hyperactive?

Yes, ODIMONT LC KID TABLET can cause certain neuropsychiatric events like behaviour and mood-related changes: agitation including aggressive behaviour or hostility, depression in some children, although not everybody gets them. Consult your child’s doctor immediately if you notice any unusual behaviour in your child during treatment with ODIMONT LC KID TABLET.  

Is ODIMONT LC KID TABLET safe to use in children with kidney problems?

ODIMONT LC KID TABLET is not recommended for use in children with severe impairment of kidney function and should be used with caution in children with impaired kidney function. Consult your child’s doctor for advice before administration of ODIMONT LC KID TABLET to your child.

REFERENCES

1. KD. Tripathi. Histamines and Antihistamines & Drugs for cough and bronchial asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 166-168 & 228-229.

2. Peter J. Barnes. Pulmonary pharmacology. Randal A. Skidgel, Allen P. Kaplan and Ervin G. Erdos. Histamine, Bradykinin, and their antagonists. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 918-923 & 1052-1054.

3. B Knorr, P Larson, H H Nguyen, S Holland, T F Reiss, P Chervinsky, K Blake, C H van Nispen, G Noonan, A Freeman, R Haesen, N Michiels, J D Rogers, R D Amin, J Zhao, X Xu, B C Seidenberg, B J Gertz, S Spielberg. Montelukast dose selection in 6- to 14-year-olds: comparison of single-dose pharmacokinetics in children and adults. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 1999. [Accessed on 13th October 2021] https://pubmed.ncbi.nlm.nih.gov/10434229/

4. Gary M Doherty. Is montelukast effective and well tolerated in the management of asthma in young children? Part A: Evidence-based answer and summary. NCBI; PMC US National Library of Medicine, National Institute of Health. April 2007. [Accessed on 13th October 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528689/

5. Maciej Ciebiada, Malgorzata Górska-Ciebiada, Lawrence M DuBuske, Pawel Górski. Montelukast with desloratadine or levocetirizine for the treatment of persistent allergic rhinitis. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. November 2006. [Accessed on 13th October 2021] https://pubmed.ncbi.nlm.nih.gov/17165277/

6. Montelukast for asthma. Medicines for Children. November 2014. [Accessed on 13th October 2021] https://www.medicinesforchildren.org.uk/montelukast-asthma

7. A N Pampura, N G Papadopoulos, V Spicák, R Kurzawa. Evidence for clinical safety, efficacy, and parent and physician perceptions of levocetirizine for the treatment of children with allergic disease. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2011. [Accessed on 13th October 2021] https://pubmed.ncbi.nlm.nih.gov/21346367/

8. F Estelle R Simons. Early Prevention of Asthma in Atopic Children (EPAAC) Study Group. Safety of levocetirizine treatment in young atopic children: an 18-month study. ResearchGate. October 2007. [Accessed on 13th October 2021] https://www.researchgate.net/publication/6274909_Early_Prevention_of_Asthma_in_Atopic_Children_EPAAC_Study_Group_Safety_of_levocetirizine_treatment_in_young_atopic_children_an_18-month_study

9. Fourrts. L Montus Kid Forte. Fourrts.com. [Accessed on 13th October 2021] https://www.fourrts.com/l-montus-2/

10. Merck Sharp & Dohme Limited. Electronic Medicines Compendium (EMC). [Revised in May 2020] [Accessed on 13th October 2021] https://www.medicines.org.uk/emc/files/pil.197.pdf

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count