Glaxosmithkline Pharmaceuticals Ltd

Neosporin H Ointment 5gm

Skin Infections
MRP ₹75.99 (Inclusive of all taxes)
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    Introduction About NEOSPORIN OINTMENT

    NEOSPORIN OINTMENT is a combination of Bacitracin, Hydrocortisone, Neomycin and Polymyxin B which belongs to the group of medicines called Antibacterial and Steroids. It is used to manage superficial infections of the eye where inflammation is present markedly. It is also used to manage chronic anterior uveitis and injury to the cornea due to chemicals, heat burns, radiation, or foreign body penetrations.

    Before applying NEOSPORIN OINTMENT, inform your doctor if you have glaucoma, cataract surgery, herpes simplex infection and venous stasis eczema and ulceration. NEOSPORIN OINTMENT is not recommended for use in pregnant women as safety is not established. Consult your doctor before applying it.

    NEOSPORIN OINTMENT is generally not recommended for use by breastfeeding women. Consult your doctor before applying it. NEOSPORIN OINTMENT is not recommended for use in neonates and infants under 2 years of age. NEOSPORIN OINTMENT should be used with caution in patients over the age of 65.

    The most common side effects of applying GBNKEYWORD are eye irritation, itching, redness, and swelling of the conjunctiva and eyelid. Contact your physician if any of the symptoms worsen.

    Uses Of NEOSPORIN OINTMENT

    • Manage superficial infections of the eye, where inflammation is present markedly
    • Manage chronic anterior uveitis and injury to the cornea due to chemicals, heat burns, radiation, or foreign body penetrations

    How NEOSPORIN OINTMENT Works

    NEOSPORIN OINTMENT helps to manage eye infections, whereas Bacitracin is an antibacterial that works by inhibiting the growth of bacteria by managing the formation of the cell wall. Hydrocortisone is a steroid that blocks the production of certain chemical messengers called prostaglandins (which are responsible for pain, inflammation, and allergy). Neomycin is an aminoglycoside antibiotic that works by inhibiting protein synthesis, causing cell death, and Polymyxin B is an antibacterial that works by damaging the cell membrane of bacteria (which is essential for their survival), leading to death. They effectively manage eye infections when used together. 

    How to use NEOSPORIN OINTMENT

    Apply NEOSPORIN OINTMENT as directed by your physician. It is for external use only. Wash your hands with soap and water before and after using NEOSPORIN OINTMENT. Apply a thin layer of this medicine to the affected eye.

    Side Effects Of NEOSPORIN OINTMENT

    Common

    • allergic reactions, eye irritation, itching, redness and swelling of the conjunctiva and eyelid

    Rare

    Stop applying NEOSPORIN OINTMENT and contact your physician immediately if you experience any of the following side effects:

    • serious allergic reactions such as anaphylaxis
    • symptoms of pseudomembranous colitis such as prolonged diarrhoea, abdominal cramps
    • inflammation, irritation or pain persists

    Warning & Precautions

    Pregnancy

     NEOSPORIN OINTMENT is not recommended for use in pregnant women as safety is not established. Consult your doctor before applying it.

    Breastfeeding

    NEOSPORIN OINTMENT is generally not recommended for use in breastfeeding women. Consult your doctor before applying it.

    Kidney

    NEOSPORIN OINTMENT should be used with caution in patients with kidney disease. Contact your doctor before applying it.

    Allergy

    Do not apply NEOSPORIN OINTMENT if you are allergic to bacitracin, hydrocortisone, neomycin and polymyxin B or mineral oils or neomycin, framycetin, kanamycin, paromomycin, streptomycin, and gentamycin, or other ingredients of the medicine

    Lungs

     NEOSPORIN OINTMENT is not recommended for use in patients with tuberculosis infection. Contact your doctor before applying it.

    Others

    NEOSPORIN OINTMENT is not recommended for use if you have:

    • pre-existing nerve deafness
    • perforated tympanic membrane
    • epithelial herpes simplex keratitis (dendritic keratitis)
    • vaccinia and varicella infections
    • tuberculous infection of the eye
    • bacterial and fungal diseases of the eye
    • viral, bacterial, and fungal infections of the skin
    • surgery

    Before applying NEOSPORIN OINTMENT, inform your doctor if you have:

    • pituitary-adrenal axis suppression
    • blurred vision
    • colitis
    • glaucoma
    • cataract surgery
    • herpes simplex infection
    • venous stasis eczema and ulceration

    Use in paediatrics: NEOSPORIN OINTMENT is not recommended for use in neonates and infants under 2 years of age. Consult your doctor before applying it.

    Use in geriatrics: NEOSPORIN OINTMENT should be used with caution in elderly patients aged 65 years or above. Contact your doctor before applying it.

    Interactions

    A. Drug-Drug interactions: Tell your doctor if you are applying or have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplements or herbal products

    • aminoglycoside antibiotic Ex. amikacin, gentamycin (medicines used for bacterial infections)
    • neuromuscular blocking agents Ex. succinylcholine (medicines used in anaesthesia)

    Overdosage:

    If you or anyone else accidentally take too much of NEOSPORIN OINTMENT, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :   Bacitracin, Hydrocortisone, Neomycin and Polymyxin B
    Pharmacological Category :   Antibacterial and Steroids
    Therapeutic Indication :   Eye infections
    Dosage Forms :   Ointment, Eye Ointment, Cream

    More Information

    • Keep NEOSPORIN OINTMENT out of the sight and reach from children
    • Store NEOSPORIN OINTMENT below 30°C

    FAQs About NEOSPORIN OINTMENT

    Q: Does NEOSPORIN OINTMENT cause glaucoma?

    A: Yes. Prolonged use of NEOSPORIN OINTMENT may increase eye pressure, resulting in glaucoma. Contact your doctor before applying it.

    Q: For what conditions is NEOSPORIN OINTMENT used?

    A: NEOSPORIN OINTMENT is used to manage superficial infections of the eye where inflammation is present. It is also used to manage chronic anterior uveitis and injuries to the cornea due to chemicals, heat burns, radiation, or foreign body penetrations. Contact your doctor before applying it.

    Q: Does NEOSPORIN OINTMENT cause blurred vision?

    A: Yes. NEOSPORIN OINTMENT may cause blurred vision due to serious central chorioretinopathy. Contact your doctor before applying it.

    Q: Can I use NEOSPORIN OINTMENT long-term?

    A: No. NEOSPORIN OINTMENT should not be continued for more than seven days in the absence of any clinical improvement, and it may lead to unwanted effects when used long-term. Contact your doctor if symptoms persist.

    Q: What are the side effects of using NEOSPORIN OINTMENT?

    A: The most common side effects of applying GBNKEYWORD are eye irritation, itching, redness, and swelling of the conjunctiva and eyelid. Contact your physician if any of the symptoms worsen.

    Q: How to apply NEOSPORIN OINTMENT

    A: Apply NEOSPORIN OINTMENT as directed by your physician. It is for external use only. Wash your hands with soap and water before and after using NEOSPORIN OINTMENT. Apply a thin layer of this medicine to the affected eye.

    References

    1. KD Tripathi. Antimicrobial Drugs, Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 759, 750, 895.

    2. Bethesda (MD). Bacitracin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 11th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/57402735

    3. Bethesda (MD). Polymyxin B. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 11th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/49800004

    4. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 11th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/8378

    5. GlaxoSmithKline Pharmaceuticals Limited. Bacitracin, Hydrocortisone, Neomycin and Polymyxin B. [Revised in September 2020] [Accessed on 15th July 2022] https://india-pharma.gsk.com/media/6391/neosporin-h-ointment.pdf

    6. Leeford Health care. Nosramycin- H eye ointment (Bacitracin, Hydrocortisone, Neomycin and Polymyxin B. [Accessed on 15th July 2022] https://www.leeford.in/product/1287/nosramycin-h-eye-ointment

    7. Bausch & Lomb Incorporated. Bacitracin, Hydrocortisone, Neomycin and Polymyxin B. [Revised in November 2016] [Accessed on 15th July 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3b00eb5c-dd98-467e-a883-04c37a8ecc42&type=display

    Author Details

    Written By Dr. Dhivakaran R - BDS
    Reviewed For Accuracy By Dr. Karthikeyan Rajagopal - M. Pharma, Ph.D (Pharmacology)
    Last updated on 03 Jan 2023 | 05:40 PM(IST)
    Lab updated