INTRODUCTION

MOREASE 135MG contains Mebeverine hydrochloride which belongs to a group of medicines called antispasmodics. It helps to relax the muscles of the gastro-intestinal tract (gut). Anticholinergics are a group of medicines which acts on the neurotransmitter, acetylcholine. They are also called antispasmodics. Anticholinergics prevent impulses from the parasympathetic nervous system from reaching the smooth muscle by blocking the action of acetylcholine which is responsible for contractions, cramps or spasms.

It is used in conditions such as irritable bowel syndrome and similar problems such as chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Irritable bowel syndrome (IBS) is a very common condition which causes spasm and pain in the gut or intestine. The intestine is long muscular tube which food passes down and so it can be digested. If the intestine goes into spasm and squeezes too tightly, you get pain. This medicine works by relieving the spasm, pain and other symptoms of IBS. Most people will not have problems with this medicine, but some may get some side effects, such as difficulty in breathing, swelling of face, neck, tongue or throat, skin rash, red itchy skin.

USES OF MOREASE 135MG

• Treats irritable bowel syndrome and similar problems such as chronic irritable colon, spastic constipation, mucous colitis and spastic colitis
• Relax the muscles of the gastro-intestinal tract (gut)

HOW MOREASE 135MG WORKS

Mebeverine is an antispasmodic with a direct action on the smooth muscle of the gastrointestinal tract. This medicine prevents impulses from the parasympathetic nervous system from reaching the smooth muscle by blocking the action of acetylcholine which is responsible for contractions, cramps or spasms.

DIRECTIONS FOR USE

It should be taken about 20 minutes before a meal or as your doctor told you. Swallow the medicine whole with water. Do not chew the medicine.

SIDE EFFECTS OF MOREASE 135MG

HOW TO MANAGE SIDE EFFECTS

Skin redness:

Avoid hot showers or baths because hot water can irritate the skin. Moisturizers can be used on regular basis to soothe and hydrate the affected area.

Headache:

Rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, dark room.

Constipation:

Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or recently taken any other medicines, including medicines obtained without a prescription.

SYNOPSIS

MORE INFORMATION

Store between 15-30°C and keep out of reach of children.

FAQs ABOUT MOREASE 135MG

How long does it take to work?

It usually works within an hour or so to ease symptoms. Their effectiveness may depend on the dose you are given and how often you take them.

Does MOREASE 135MG help with gas?

It is an antispasmodic medicine which is taken to relieve bloating and crampy pain in the lower tummy (abdomen). These symptoms are commonly associated with the gastrointestinal condition called irritable bowel syndrome. It works on certain muscles in the wall of your intestines, causing them to relax.

REFERENCES

1. Anita Annaházi, Richárd Róka, András Rosztóczy and Tibor Wittmann; Role of antispasmodics in the treatment of irritable bowel syndrome; [Revised on 2014] [Accessed 29 Sep 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033443/

2. Goodman and Gilman’s: The Pharmacological Basis of Therapeutics. Chapter – 46 – Treatments of disorders of bowel motility and water reflux; 12th ed. New York, New York: McGraw-Hill Medical, 2011. Page – 1341.

3. APL Swift Services (Malta) Ltd; Electronic Medicines Compendium (EMC); [Revised on 10/2020] [Accessed 29 Sep 2020] https://www.medicines.org.uk/emc/files/pil.2315.pdf

4. Hawke’s Bay Hospital Pharmacy; Hawkesbay health; [Revised on 10/2014] [Accessed 29 Sep 2020] https://www.hawkesbay.health.nz/assets/Patient-Medication-Information/Mebeverine-PIL.pdf