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INTRODUCTION
MONOGUARD SHAMPOO is a combination of Sertaconazole and Zinc pyrithione which belongs to the group of medicines called Antifungal and Antimicrobial agents. It is used to treat seborrheic dermatitis of the scalp in adults.
Seborrheic dermatitis is a common skin condition that mainly affects your scalp. It causes scaly patches, inflamed skin and stubborn dandruff. It usually affects oily areas of the body, such as the face, sides of the nose, eyebrows, ears, eyelids and chest.
Your doctor might want you to drink plenty of water during the treatment as hydrating the body may reduce the number of flakes on the scalp.
MONOGUARD SHAMPOO is not recommended for use in children and adolescents below 12 years of age.
Safety and efficiency of MONOGUARD SHAMPOO in pregnant and breastfeeding women has not been established yet. Consult your doctor before using it.
The most common side effects of using MONOGUARD SHAMPOO can be irritation at the application site. Consult your doctor if the condition worsens.
USES OF MONOGUARD SHAMPOO
- Used to treat seborrheic dermatitis of the scalp
HOW MONOGUARD SHAMPOO WORKS
MONOGUARD SHAMPOO works by slowing the growth of fungi that causes infection. Sertaconazole acts primarily by inhibiting the cytochrome P450-dependent synthesis of ergosterol (key component of cell membrane of fungi) and lack of this component leads to fungal cell injury. Zinc pyrithione mediates its action by increasing the cellular levels of copper and damaging the iron-sulfur cluster of proteins needed for fungal metabolism and growth.
DIRECTIONS FOR USE
Use MONOGUARD SHAMPOO as advised by your physician. It is for external use only. Wet hair with enough water. Massage to lather and leave it on the scalp and hair for a few minutes. Avoid contact with the eyes. Your doctor will decide the right dose and duration depending upon your age, body weight and disease condition. Check the label for directions before use.
SIDE EFFECTS OF MONOGUARD SHAMPOO
COMMON
- dryness of treated skin
- skin tenderness
- mild rash or skin irritation
RARE
Stop using and contact your doctor immediately if you experience the following:
- severe burning, redness, or stinging
- itching or blistering skin
- signs of an allergic reaction (rash, hives, red, swollen, blistered, or peeling skin with or without fever, wheezing, tightness in the chest or throat, trouble breathing, swallowing, or talking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat)
- swelling or oozing from the skin
WARNING & PRECAUTIONS
PREGNANCY
Safety and efficacy of MONOGUARD SHAMPOO during pregnancy has not been established yet. Consult your doctor before applying it.
BREASTFEEDING
Safety and efficacy of MONOGUARD SHAMPOO during breastfeeding has not been established yet. Consult your doctor before applying it.
ALLERGY
Do not use MONOGUARD SHAMPOO if you are allergic to Sertaconazole or Zinc pyrithione or any ingredients of this medicine.
OTHERS
MONOGUARD SHAMPOO is not recommended for use in children and adolescents below 12 years of age. Consult your doctor before applying it.
INTERACTIONS
A. Drug - Drug interactions:
Before using MONOGUARD SHAMPOO inform your doctor if you are taking any herbal supplements, vitamins or over the counter medicines.
Overdosage:
If you or anyone else accidentally ingest MONOGUARD SHAMPOO, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Sertaconazole, Zinc pyrithione |
| Pharmacological Category | : | Antifungal and Antimicrobial agents |
| Therapeutic Indication | : | Seborrheic dermatitis of the scalp |
| Dosage Forms | : | Shampoo |
MORE INFORMATION
- Keep MONOGUARD SHAMPOO out of reach of children
- Store at room temperature
FAQs ABOUT MONOGUARD SHAMPOO
Can I stop using MONOGUARD SHAMPOO on my own?
No, stopping MONOGUARD SHAMPOO without consulting your doctor may worsen the condition. Consult your doctor before stopping.
Can MONOGUARD SHAMPOO be used in children?
No, MONOGUARD SHAMPOO is not recommended for use in children and adolescents below 12 years of age. Consult your doctor for advice.
How does MONOGUARD SHAMPOO work?
MONOGUARD SHAMPOO works by slowing the growth of fungi that causes infection. Sertaconazole acts primarily by inhibiting the cytochrome P450-dependent synthesis of ergosterol (key component of cell membrane of fungi) and lack of this component leads to fungal cell injury. Zinc pyrithione mediates its action by increasing the cellular levels of copper and damaging the iron-sulfur cluster of proteins needed for fungal metabolism and growth.
Should I follow any lifestyle changes while using MONOGUARD SHAMPOO?
Avoid scratching the scalp while using MONOGUARD SHAMPOO as it may worsen dandruff. Cover your head with a scarf or hat while going out. Drink plenty of water as hydrating the body may reduce the number of flakes on the scalp, thus decreasing the appearance of dandruff.
Can MONOGUARD SHAMPOO be used in pregnant women?
Safety and effectiveness of MONOGUARD SHAMPOO during pregnancy has not been established yet, consult your doctor before using it if you are pregnant while using it.
REFERENCES
1. Goodman & Gilmans. Dermatological pharmacology. The Pharmacological Basis of Therapeutics. Twelfth Edition. 2011. Page –1817.
2. DPT Laboratories Inc. U.S Food and Drug Administration. [Accessed on 10th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/21385_Ertaczo_lbl.pdf
3. Sertaconazole, Zinc pyrithione. Mayoclinic. [Revised in September 2021] [Accessed on 10th June 2022] https://www.mayoclinic.org/diseases-conditions/dandruff/symptoms-causes/syc-20353850
4. Zinc pyrithione Drugbank. [Accessed on 10th June 2022] https://go.drugbank.com/drugs/DB06815
5. Zinc pyrithione. Drugs.com. [Revised in October 2021] [Accessed on10th June 2022] https://www.drugs.com/cdi/pyrithione-zinc-shampoo.html
6. Sertaconazole. Medlineplus. [Revised on September 2016] [Accessed on 10th June 2022] https://medlineplus.gov/druginfo/meds/a608047.html
7. Sertaconazole. Drugs.com. [Revised on May 2022] [Accessed on 10th June 2022] https://www.drugs.com/mtm/sertaconazole-topical.html#interactions
AUTHOR DETAILS
Written By Dr. Janet.C, Pharm.D
Last updated on 23 Dec 2022 | 03:56 PM(IST)
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