METOZ 2.5MG contains metolazone which is a diuretic antihypertensive drug used for the treatment of edema. They are usually prescribed to treat high blood pressure, fluid retention (oedema) or heart failure. It removes fluid from the body by increasing urine production. It works by causing you to urinate more which helps to remove excess fluid and salt from your body. Removing this excess fluid and salt also helps to lower your blood pressure. It effectively increases the excretion of phosphate and magnesium ions, and sodium in patients with severely compromised glomerular filtration.
Take this medicine with same meal each day or as directed by physician. Swallow the medicine whole with water. Do not chew the medicine. The most common side effects include constipation, dry mouth, diarrhea, headache, stomach pain, and blurred vision. It is contraindicated in anuria, in hepatic coma or pre-coma, and in cases of known allergy and hypersensitivity to metolazone.
It works by causing you to urinate more which helps to remove excess fluid and salt from your body. Removing this excess fluid and salt also helps to lower your blood pressure.
Take this medicine with same meal each day or as directed by physician. Swallow the medicine whole with water. Do not chew the medicine.
Nausea and vomiting:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Skin redness:
Avoid hot showers or baths because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.
Muscle cramps:
Stretching and massaging the muscle may help it to relax. Applying heat or cold to that area may also help to prevent muscle cramp. Avoid dehydration.
Headache:
Rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, dark room.
Constipation:
Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Diarrhea:
Drink lots of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor.
METOZ 2.5MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
METOZ 2.5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
It may cause adverse reactions affecting the ability to drive a vehicle or to operate machines, such as tiredness and dizziness. If you feel tired or drowsy, you should not drive or use machines.
Consumption of alcohol is not recommended during treatment with this medicine.
METOZ 2.5MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
METOZ 2.5MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
Do not take if you are allergic (hypersensitive) to this medicine or any other ingredients in this medicine.
METOZ 2.5MG should be taken with caution in patients with severe heart disease. Consult your doctor for advice.
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
Drug | : | Metolazone |
Pharmacological Category | : | Antihypertensive agent, Diuretic |
Therapeutic Indication | : | Oedema |
Dosage Forms | : | Tablet |
Store at room temperature 15-25°C and keep it out of reach of children.
How long does it take for METOZ 2.5MG to work?
It usually takes 3 to 4 days for this medicine to start reducing edema, and 3 to 6 weeks to start reducing blood pressure.
What is METOZ 2.5MG?
It is a prescription drug and is a "water pill" (diuretic) that increases the amount of urine you make, which causes your body to get rid of excess water. It is used to treat high blood pressure.
1. Domenic A. Sica MD; Metolazone and Its Role in Edema Management; [Revised on 2007] [Accessed on 30 Sep 2020] https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1527-5299.2003.01907.x
2. K.D.Tripathi, Essentials of medical pharmacology, Drugs acting on kidney, Chapter 41 –Diuretics, Page – 583.
3. Aine McManus WUTH; U.K. NHS; [Revised on Aug 2020] [Accessed on 30 Sep 2020] https://mm.wirral.nhs.uk/document_uploads/shared-care/Metolazone-for-CKD-SCG-v2.pdf
4. sanofi-aventis Canada Inc; Zaroxolyn Product Monograph; [Revised on Feb 2018] [Accessed on 30 Sep 2020] http://products.sanofi.ca/en/zaroxolyn.pdf
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