Metatop Nasal Spray 120Md

Nasal Congestion Rx required

Best Price*  ₹ 329.12
MRP ₹411.40
(Inclusive of all taxes) * Mkt: Cadila Healthcare Ltd (Zydus) * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

METATOP contains a medicine called mometasone which belongs to a group of medicines called antiallergic agents. It is used in the prevention and treatment of nasal symptoms of allergic rhinitis such as nasal congestion, irritation and itching in adults and in children aged 2 years and above. It can also be used to treat nasal polyps in adults. Mometasone inhibits the expression of proinflammatory genes and decreases the production of inflammatory mediators associated with the allergic response. It is a corticosteroid which has an anti-inflammatory action, reducing swelling and irritation which causes sneezing, itching and a blocked or runny nose.

Along with this treatment, try not to garden or farm often if you have problems with mold. Keep away from your pets. Don't rake, mow, or blow leaves, flowers or pollens. Avoid outdoor activities when allergen level is high. Close windows and stay indoors when pollen counts are high. The most common side effect of taking this medicine are headache, sneezing and nose bleeds. Before taking this medicine, inform your doctor if you have nasal problems, eye disease, infections or cystic fibrosis. Contact your doctor before taking this medicine, if you are pregnant or breast-feeding.

USES OF METATOP

  • Prevents and treats allergic rhinitis in adults and children 2 years of age and above
  • Treats nasal polyps in adults

HOW METATOP WORKS

Mometasone has anti-inflammatory, antipruritic and vasoconstrictive properties. It diffuses across the cell membrane and binds to glucocorticoid receptors, which facilitates the movement of receptor into the nucleus. Once inside the nucleus, receptors dimerize and binds to a DNA sequence known as glucocorticoid response element, which inhibits the expression of proinflammatory genes such as interleukin-4 and 5 and nuclear factor-kappa-B, which significantly reduces the allergic response. Additionally, it decreases the production mediators like histamine, eicosanoids, leukotrienes and cytokines which relives from sneezing, itching and a blocked or runny nose.

DIRECTIONS FOR USE

Always use this medicine as directed by your physician. It is for intranasal use only. Initially, prime your nasal spray by pumping the spray 10 times until a fine mist is produced. Gently shake the bottle. Place your finger on one of the nostrils and put the nozzle in your other nostril. Tilt your head forward and press the spray. Breath out through your mouth. Repeat the same steps for the other nostril if required. Once after using, wipe the nozzle with a clean tissue and replace the dust cap. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF METATOP

SERIOUS

  • severe allergic reactions such as swollen face, tongue or pharynx, difficulty in swallowing, itching, wheezing

COMMON

  • headache
  • sneezing
  • nose bleeds
  • sore nose or throat
  • respiratory tract infection

HOW TO MANAGE SIDE EFFECTS

Headache:  

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Sneezing:

Try not to garden or farm often if you have problems with mold. Keep away from your pets. Don't rake, mow, or blow leaves, flowers or pollens. Avoid outdoor activities when allergen level is high. Close windows and stay indoors when pollen counts are high. If symptoms persist, contact your doctor.

WARNING & PRECAUTIONS

PREGNANCY

METATOP should be used with caution in pregnant women. Consult your doctor before taking this medicine.

BREASTFEEDING

METATOP should be used with caution in breastfeeding women. Consult your doctor before taking this medicine.

ALLERGY

Do not use this medicine if you are allergic (hypersensitive) to mometasone.

OTHERS

Before taking this medicine, inform your doctor if you:

  • have nasal problems (nasal infection, nasal sores, nasal surgery or nasal injury), eye disease (glaucoma), infections (tuberculosis, chickenpox or measles) or cystic fibrosis

INTERACTIONS

Talk to your doctor, if you are taking,

  • other corticosteroid medicine by mouth or injection (e.g. dexamethasone)

SYNOPSIS

Drug :   Mometasone
Pharmacological Category :   Topical corticosteroids
Therapeutic Indication :   Psoriasis, Atopic dermatitis
Dosage Forms :   Cream, Ointment, lotion, Nasal spray

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT METATOP

Can METATOP be used in children?

Yes. It can be used in children aged 2 years and above. It is strictly not recommended for use in children aged below 2 years. Consult your doctor for advice.

Can METATOP be used during pregnancy?

This medicine must be used with caution in pregnant women. Consult your doctor for advice.

REFERENCES

1. KD. Tripathi. Drugs acting on skin and mucous membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895-896.

2. Bernard P. Schimmer and John W. Funder. ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1226.

3. George P. Chrousos. Adrenocorticosteroids & Adrenocortical Antagonists. Basic and Clinical Pharmacology. 14th Edition. New York McGarw Hill Education 2018.  Page – 714.

4. Gerald G. Briggs and Roger K. Freeman. M. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 2626-2628.

5. Merck Sharp & Dohme Corp. A Study of Long-term Administration of Mometasone Furoate Nasal Spray in Pediatric Subjects with Perennial Allergic Rhinitis (Study P06333AM1). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on April 2017] [Accessed 26th November 2020] https://clinicaltrials.gov/ct2/show/NCT01165424

6. Actavis Inc. Clinical Equivalence Study of Mometasone Nasal Spray. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on August 2020] [Accessed 26th November 2020] https://clinicaltrials.gov/ct2/show/NCT01850823

7. Merck Sharp & Dohme Corp. Study of Nasonex in the Relief of Nasal Congestion in Patients with Seasonal Allergic Rhinitis (Study P05583). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on September 2016] [Accessed 26th November 2020] https://clinicaltrials.gov/ct2/show/NCT00728416

8. Desiderio Passali, Maria Carla Spinosi, Anna Crisanti, and Luisa Maria Bellussi. Mometasone furoate nasal spray: a systematic review. NCBI; PMC US National Library of Medicine, National Institute of Health. May 2016. [Accessed 26th November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852427/

9. Pharmadox Healthcare Ltd, S&D Pharma CZ, spol. s r.o, Cipla (EU) Limited and Cipla Europe NV. Electronic Medicines Compendium (EMC); [Revised on November 2017] [Accessed 26th November 2020] https://www.medicines.org.uk/emc/files/pil.10299.pdf

10. Schering Corporation, a subsidiary of Merck & Co. U.S. Food & Drug Administration; [Revised on January 2011] [Accessed 26th November 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020762s044lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • Allergen-specific Immunoglobulin E antibody test (radioallergosorbent test) 

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    50
    Ingredient
    MOMETASONE FUROATE 0.05%W/V
    Hsn Code
    30049094
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Metatop Nasal Spray 120Md

Metatop Nasal Spray 120Md Mkt: Cadila Healthcare Ltd (Zydus)

M.R.P.: Rs.411.40
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