Losar 50mg Tablet 15'S

Introduction About LOSAR 50MG TABLET

Losar 50mg Tablet contains Losartan, an angiotensin II receptor blocker (ARB) used to manage high blood pressure (hypertension). It helps reduce strokes, heart attacks, and kidney problems in patients with diabetes.

Losar 50mg Tablet can be prescribed on its own or alongside other medications. It can be taken with or without food, at any time-of-day morning or night. However, it is best to take it at the same time each day to maximize its effectiveness. Even if you feel well or your blood pressure appears under control, it is important to keep taking it regularly. High blood pressure often does not cause noticeable symptoms, but stopping the medication could make your condition worse. This medicine is commonly used and is generally considered safe for long-term use.

Making certain lifestyle changes can also help lower your blood pressure. These may include exercising regularly, losing weight, quitting smoking, limiting alcohol consumption, and reducing salt intake as recommended by your doctor. Most patients tolerate this medication well, and it typically has few side effects. Some common side effect of this medication includes dizziness, headache, back pain, nasal congestion, tiredness, abdominal pain, constipation, and diarrhoea. Inform your doctor if these side effects persist or become bothersome.

Before starting this medication, inform your doctor if you have any kidney or liver problems. If you are pregnant or breastfeeding, it is important to consult your doctor beforehand. During management, your doctor may regularly monitor your kidney function, blood pressure, and blood potassium levels.

Uses Of LOSAR 50MG TABLET

• High blood pressure (hypertension)

Benefits of LOSAR 50MG TABLET

1) Effectively Lowers High Blood Pressure: Losar 50mg helps relax blood vessels, allowing blood to flow more easily. This leads to a reduction in blood pressure, which lowers the risk of serious cardiovascular complications over time.

02) Reduces the Risk of Heart Attack and Stroke: By controlling blood pressure and reducing strain on the heart and arteries, Losar significantly decreases the risk of heart attacks, strokes, and other related conditions in high-risk individuals.

03) Protects Kidney Function in Diabetic Patients: Losar 50mg is especially beneficial for people with type 2 diabetes who also have high blood pressure. It helps slow the progression of kidney damage, a common complication of diabetes.

04)Well-Tolerated with Minimal Side Effects: Most patients tolerate Losar well. Common side effects, if they occur, are usually mild and include dizziness, fatigue, or nasal congestion. Serious side effects are rare.

05) Convenient Once-Daily Dosage: With just one tablet a day, Losar 50mg offers a simple, effective way to manage chronic conditions, improving medication adherence and overall outcomes.

How LOSAR 50MG TABLET Works

Losar 50mg Tablet contains losartan potassium, an angiotensin II receptor blocker (ARB) that works by relaxing blood vessels so that blood can flow more easily. It blocks the action of a chemical called angiotensin II, which normally causes blood vessels to tighten. By reducing this tightening, Losar lowers blood pressure, reduces the strain on the heart, and improves blood flow, making it effective for managing high blood pressure (hypertension) and helping to protect the kidneys in patients with diabetes.

How to use LOSAR 50MG TABLET

Follow your doctor's instructions regarding the exact dosage. Do not exceed the recommended daily dosage.

How to Take Losar 50mg Tablet?

• Take one tablet daily with or without food.
• Swallow the tablet whole with a glass of water. Do not crush or chew the medication.
• For best results, take the tablet at the same time each day.

What if I forgot to take LOSAR 50MG TABLET

• If you forget to take your dose, take it as soon as you remember.
• Do not take two doses to make up for a missed dose. This could increase your risk of side effects.
• If it is almost time for your next dose, skip the missed dose and take your regular dose at the usual time.

Side Effects Of LOSAR 50MG TABLET

Like all medicines, Losar 50mg Tablet may cause certain side effects in some individuals, although not everybody gets them.

The most common side effects of taking Losar 50mg Tablet are:

• Dizziness
• Headache
• Back pain
• Nasal congestion
• Tiredness
• Abdominal pain
• Constipation
• Diarrhoea

When to consult your doctor?

• Severe allergic reactions symptoms such as rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
• Low blood pressure symptoms such as severe dizziness or fainting
• Cardiovascular problem symptoms such as tightness, pain, or pressure in the chest, irregular, or fast heartbeat
• Severe kidney problems symptoms such as decreased urine output, swelling in the legs or ankles, fatigue, nausea
• Hyperkalemia (High Potassium Levels) symptoms such as muscle weakness, irregular heartbeats, numbness, or tingling
• Jaundice symptoms such as yellowing of the skin or eyes, dark urine, fatigue

How To Manage Side Effects

Diarrhea

• Drink Fluids: Drink clear fluids such as water, broths, and oral rehydration solutions (ORS).
• Electrolytes: If you are losing a lot of fluids (for example, from frequent diarrhea), consider drinking an electrolyte solution to help replenish lost minerals like potassium and sodium.
• BRAT Diet: Try to take Bananas, Rice (white rice), Apple sauce and Toast (plain, without butter) to control diarrhoea management.
• Avoid Certain Foods: While recovering avoid the following food items such as fatty, greasy, or fried foods, spicy foods, dairy products (especially if you have a temporary lactose intolerance), caffeinated drinks and alcohol and artificial sweeteners like sorbitol.
• Over-the-Counter Medications: You can take over-the-counter anti-diarrheal medications such as loperamide, Bismuth subsalicylate if appropriate for you. Follow the recommended dosage.

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down, or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Headache

• Rest in a Quiet, Dark Room: Find a calm, quiet space away from bright lights and loud noises. Lie down and close your eyes.
• Hydrate: Dehydration can contribute to headaches, so drink plenty of water.
• Apply a Cold or Warm Compress: A cold pack on your forehead may reduce pain, or a warm compress on your neck or shoulders can relieve tension.
• Over-the-Counter Pain Relief: You can take over-the-counter pain relievers like acetaminophen or ibuprofen if appropriate for you. Follow the recommended dosage.
• Practice Relaxation Techniques: Deep breathing exercises, meditation, or gentle stretching can help reduce stress and alleviate headache symptoms.

Warning & Precautions

Pregnancy

Contraindicated

Losar 50mg Tablet is not recommended for use in pregnant women. It is important to consult your doctor before taking this medication.

Breastfeeding

Consult your doctor

It is not known whether the medicine is excreted in human milk. It is important to consult your doctor before taking this medication.

Driving and Using Machines

Use with Caution

Do not drive or operate machines if you experience dizziness or drowsiness after taking Losar 50mg tablet.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking Losar 50mg tablet since it may increase the risk of blood pressure and kidney function.

Kidney

Consult your doctor

Losar 50mg tablet is not recommended for use in patients with impaired kidney function and should be taken with caution in patients with narrowing of blood vessels to one or both the kidneys and in patients who had recently received kidney transplant. Consult your doctor before taking it.

Liver

Consult your doctor

Losar 50mg tablet is not recommended for use in patients with severely impaired liver function and should be used with caution in patients having impaired liver function. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take this medication if you are allergic to Losartan and/or any other ingredients of this medicine.

Heart Disease

Use with Caution

Losar 50mg tablet should be taken with caution in patients having heart failure, problems in heart valve and heart muscle, cardiac arrythmia (irregular and fast heartbeat), coronary heart disease. Consult your doctor before taking it.

Use In Pediatrics

Consult your doctor

Losar 50mg tablet is not recommended for use in children under 6 years of age and in children suffering from kidney and/or liver problems. The medicine is recommended for used in children and adolescents (aged 6 to 18 years). Consult your pediatrician before giving it.

Use In Geriatrics

Use with Caution

Losar 50mg tablet should be used with caution in patients (aged 75 years and above). Consult your doctor before taking it.

Other Warnings for LOSAR 50MG TABLET

Before taking Losar 50mg tablet, inform your doctor if you:

• have a history of angioedema (swelling of the face, lips, throat, and/or tongue)
• suffer from excessive vomiting/diarrhoea leading to extreme loss of fluid and/or salt in your body
• suffer from primary hyperaldosteronism (a syndrome associated with increased secretion of aldosterone hormone)
• suffer from cerebrovascular disease (caused by a reduced blood circulation to the brain)
• salt-restricted diet

Who should not take [GBNKEYWORD

Losar 50mg tablet is not recommended for use if you have:

• diabetes and managed with blood pressure lowering medicine containing aliskiren

Safety Advice

• Follow your doctor's instructions regarding the exact dosage.
• Do not exceed the recommended daily dosage. 
• Take one tablet daily with or without food.
• Swallow the tablet whole with a glass of water. Do not crush or chew the medication.
• For best results, take the tablet at the same time each day.
• Make sure to monitor your blood pressure regularly, particularly during the early stages of management, to ensure the medication is working properly.
• Losartan can affect electrolyte levels, such as potassium, so it is crucial to stay hydrated and follow your doctor's instructions for regular blood tests.
• Unless your doctor advises differently, avoid consuming too many potassium-rich foods or salt substitutes that contain potassium.
• Alcohol can amplify the blood pressure-lowering effects of Losartan, which may raise the risk of dizziness and fainting. It is important to limit alcohol consumption while taking this medication.
• Losartan can impact kidney function, so it is important to regularly monitor your kidneys, especially if you have a history of kidney disease or are elderly. Inform your doctor if you notice symptoms like swelling, reduced urination, or other signs related to kidney problems.
• Let your doctor know If you are pregnant or planning to become pregnant or breastfeeding women.
• Losartan can interact with various medications, such as diuretics, potassium supplements, NSAIDs, lithium, and other blood pressure drugs. It is important to inform your doctor about all the medications, supplements, or herbal products you are taking.
• If you forget a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one. Do not take two doses at once to make up for the missed dose.

Drug - Drug interaction

Inform your physician if you are taking any of the following medicine before taking Losar 50mg Tablet:

1. Potassium-Sparing Diuretics

• Interactions: Combining Losartan with potassium-sparing diuretics (e.g., Spironolactone, Amiloride) can lead to elevated potassium levels (hyperkalemia), as both Losartan and potassium-sparing diuretics can increase potassium retention.
• Effects: Symptoms of hyperkalemia can include muscle weakness, fatigue, irregular heart rhythms (arrhythmias), and in severe cases, cardiac arrest.
• Management: Regular monitoring of serum potassium levels is crucial. If hyperkalemia develops, consider reducing or discontinuing one of the medications. Avoid using potassium supplements or salt substitutes that contain potassium. Healthcare providers may adjust the dose or recommend alternative diuretics that do not retain potassium.

2. ACE Inhibitors

• Interactions: Concomitant use of Losartan and ACE inhibitors (e.g., Enalapril, Lisinopril) may increase the risk of adverse effects like hyperkalemia and hypotension due to their combined effects on the renin-angiotensin-aldosterone system (RAAS).
• Effects: Increased risk of severe hypotension, elevated potassium levels, and kidney dysfunction (acute kidney injury).
• Management: Close monitoring of renal function (serum creatinine, eGFR) and electrolytes (especially potassium) is advised. If combination therapy is necessary, ensure appropriate dose adjustments and consider more frequent monitoring. In some cases, one medication may be reduced or discontinued.

3. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

• Interactions: NSAIDs (e.g., Ibuprofen, Naproxen) may reduce the antihypertensive effect of Losartan by impairing renal function and increasing blood pressure.
• Effects: Decreased effectiveness of Losartan in controlling blood pressure, and potential risk of kidney dysfunction.
• Management: Limit the use of NSAIDs, especially in patients with preexisting kidney conditions. If NSAID use is necessary, ensure renal function is regularly monitored and adjust the dose of Losartan if required.

4. Lithium

• Interactions: Losartan can increase lithium levels in the blood, potentially leading to lithium toxicity.
• Effects: Symptoms of lithium toxicity may include tremors, confusion, excessive thirst, frequent urination, and nausea. Severe toxicity can result in kidney damage or neurological symptoms.
• Management: Monitor lithium levels closely, especially during the initiation or dosage adjustments of Losartan. If signs of lithium toxicity appear, adjust the lithium dose and consider discontinuing or reducing Losartan.

5. Rifampin (and other CYP450 Inducers)

• Interactions: Rifampin, a potent inducer of the cytochrome P450 enzyme system, may decrease the effectiveness of Losartan by increasing its metabolism.
• Effects: Reduced blood pressure-lowering effects of Losartan.
• Management: Increased monitoring of blood pressure is advised. In some cases, the dose of Losartan may need to be adjusted. Consider alternative antibiotics or antihypertensive agents if necessary.

6. Diuretics (Thiazide Diuretics)

• Interactions: The combination of Losartan with thiazide diuretics (e.g., Hydrochlorothiazide) can have an additive antihypertensive effect, leading to a more significant reduction in blood pressure.
• Effects: Risk of symptomatic hypotension, especially after the first dose.
• Management: Start with lower doses of both medications when combined, and monitor blood pressure regularly. Ensure adequate hydration and sodium intake, as dehydration and electrolyte imbalances can further enhance hypotension.

Synopsis

More Information

1.Product Comparison

1. Losar 50mg vs. Losar-H vs

Why Losar 50mg Stands Out:

• Monotherapy Simplicity: It is a single-drug treatment, making it easier to manage and adjust for patients who do not require a diuretic.
• Less Risk of Electrolyte Imbalance: Since it lacks the diuretic, there is a lower chance of complications like dehydration or imbalanced electrolytes, which can sometimes occur with Losar-H.
• Flexibility in Dosing: Losar 50mg offers more flexibility in adjusting dosage based on the patient's response.

1. Losar 50mg Vs Temikind

Key Differences:

1. Half-Life & Dosing: Losar 50mg has a shorter half-life, which means it may require more frequent dosing to maintain steady blood pressure control, while Temikind offers a longer-acting formula, often favored for once-daily dosing.
2. Onset of Action: Losar typically takes a bit longer to show effects compared to Temikind.
3. Additional Benefits: While both drugs are primarily used for hypertension, Losar may be preferred for individuals with kidney-related issues, while Temikind is often recommended for cardiovascular protection and stroke prevention.

02. What are some heart-healthy, low-sodium diet tips for Losar?

03. What physical activities are recommended for staying active and healthy during Losar?

04. What foods or supplements should be avoided while taking Losar?

FAQs About LOSAR 50MG TABLET

References

1. KD. Tripathi. Drugs Affecting Renin-Angiotensin System and Plasma Kinins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 506

2. Sana Mulla; Waqas J. Siddiqui. Losartan. NIH National Library of Medicine. National Center for Biotechnology Information. July 2022. [Accessed on 22nd April 2025] 

3. Merck Sharp & Dohme Limited. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 22nd April 2025]

Useful Diagnostic Tests

• ECG at Home
• ECG + BP Check at Home
• Full Body Checkup with ECG & BP at Home
• Comprehensive Cardiac Risk Screening with 12 Lead ECG and BP

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 22 Apr 2025 | 03:29 PM(IST)