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INTRODUCTION
LOSACAR 25MG TABLET contains Losartan which belongs to the group of medicines called Angiotensin II receptor antagonists. LOSACAR 25MG TABLET is used to treat hypertension (high blood pressure) in adults and children & adolescents (aged 6-18 years).
It is also used to protect kidney in hypertensive type 2 diabetic patients and is also indicated for use in patients with chronic heart failure when ACE (angiotensin-converting-enzyme inhibitors) medicines becomes ineffective to treat the disease. LOSACAR 25MG TABLET is also used to decrease the risk of stroke in patients with high blood pressure and thickening of left ventricle.
LOSACAR 25MG TABLET is not recommended for use in patients allergic to Losartan. It is also not recommended for use in patients with severely impaired liver function and kidney function.
Before taking LOSACAR 25MG TABLET, inform your doctor if you have a history of angioedema (swelling of the face, lips, throat and/or tongue) and/or suffering from excessive vomiting/diarrhoea, primary hyperaldosteronism (a syndrome associated with increased secretion of aldosterone hormone), kidney problems (such as narrowing of blood vessels to one or both the kidneys and/or heart problems (such as heart failure, cardiac arrythmia and coronary heart disease).
LOSACAR 25MG TABLET is not recommended for use in early pregnancy and must not be taken when a woman is more than 3 months pregnant since it may cause serious harm to the baby if used after 3-months of pregnancy. It is also not recommended for use in breastfeeding women since the medicine may pass through breastmilk.
LOSACAR 25MG TABLET is not recommended for use in children under 6 years and should be used with caution in children and adolescent (aged 6-18 years). It should be used with caution in patients (aged above 75-years) after consulting the doctor.
The most common side effects of taking LOSACAR 25MG TABLET are dizziness, general weakness, tiredness, low blood sugar (associated with signs such as fast heartbeat, shaking, sweating), changes in kidney function (associated with signs such as decreased urine output, oedema, shortness of breath) and/or anaemia. Consult your doctor if any of these symptoms worsens.
USES OF LOSACAR 25MG TABLET
- Treats hypertension in adults and children & adolescents (aged 6 to 18 years)
- Protects kidney in hypertensive type 2 diabetic patients
- Treats chronic heart failure in patients (in whom ACE inhibitors becomes ineffective to treat the disease)
- Reduces risk of stroke (in patients with high blood pressure and thickening of the left ventricle)
HOW LOSACAR 25MG TABLET WORKS
LOSACAR 25MG TABLET blocks the effects of Angiotensin II (substance produced in your body which causes narrowing of blood vessels), which leads to relaxation of blood vessels resulting in low blood pressure in affected individuals.
DIRECTIONS FOR USE
Take LOSACAR 25MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF LOSACAR 25MG TABLET
COMMON
- dizziness, general weakness, tiredness
- low blood pressure orthostatic hypotension (low blood pressure that occurs when rising from a lying/sitting position)
- signs of low blood sugar such as fast heartbeat, shaking, sweating and/or hunger
- signs of changes in kidney function (including kidney failure) such as decreased urine output, oedema, shortness of breath
- anaemia
UNCOMMON
- excessive sleepiness, headache, sleep disorders, shortness of breath
- feeling of increased heart rate, severe chest pain
- abdominal pain, constipation, diarrhoea, nausea, vomiting
- red itchy welts, itching, rash
- localised swelling (oedema)
- cough
RARE
- signs of hypersensitivity reactions (immune mediated reaction) such as skin rash, itching, fever and/or swelling
- angioedema (swelling underneath the skin)
- inflammation of blood vessels (including Henoch-Schonlein purpura)
- numbness/tingling sensation
- fainting
- very rapid and irregular heartbeat
- stroke
- signs of inflammation of the liver such as jaundice, feel sick, abdominal pain
Stop taking LOSACAR 25MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of severe allergic reactions such as rash, itching, swelling of the face, lips, mouth/throat that may cause difficulty in swallowing or breathing
HOW TO MANAGE SIDE EFFECTS
Dizziness:
Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.
Tiredness:
Make sure you take rest and drink plenty of fluids. Avoid or limit the consumption of alcohol. Try to take LOSACAR 25MG TABLET at a time when you can sit down (or lie down) when the symptoms are at their worst. Avoid driving or using tools or machinery until you feel well.
Nausea/Vomiting:
Take LOSACAR 25MG TABLET with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Talk with your doctor if the condition worsens.
Diarrhea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Tiredness:
Drink plenty of fluid and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. If the symptom does not improve consult your doctor.
Headache:
If LOSACAR 25MG TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking LOSACAR 25MG TABLET. If it lasts more than a week or severe, inform your doctor.
Constipation:
Try to eat high-fiber foods such as vegetables, cereals, fresh fruit and drink plenty of water. Involve in regular exercise (going for a daily walk/run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.
WARNING & PRECAUTIONS
PREGNANCY
LOSACAR 25MG TABLET is not recommended in early pregnancy and must not be taken when more than 3 months pregnant, as it may cause serious harm to the baby if used after 3months of pregnancy. Consult your doctor before taking LOSACAR 25MG TABLET.
BREASTFEEDING
LOSACAR 25MG TABLET is not recommended for use in breastfeeding women. Your doctor may choose another treatment especially if you want to breast-feed when your baby is a new-born/born prematurely. Consult your doctor before taking LOSACAR 25MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy or drowsy after taking LOSACAR 25MG TABLET.
KIDNEY
LOSACAR 25MG TABLET is not recommended for use in patients with impaired kidney function. It should be taken with caution in patients with narrowing of blood vessels to one or both the kidneys and in patients who had recently received kidney transplant. Consult your doctor before taking this medicine.
LIVER
LOSACAR 25MG TABLET is not recommended for use in patients with severely impaired liver function. It should be used with caution in patients having impaired liver function. Consult your doctor before taking LOSACAR 25MG TABLET.
ALLERGY
Do not take LOSACAR 25MG TABLET if you are allergic to Losartan and/or any other ingredients of this medicine.
HEART DISEASE
LOSACAR 25MG TABLET should be taken with caution in patients having heart failure, problems in heart valve and heart muscle, cardiac arrythmia (irregular and fast heartbeat), coronary heart disease. Consult your doctor before taking LOSACAR 25MG TABLET.
OTHERS
LOSACAR 25MG TABLET is not recommended for use if you have:
- diabetes and treated with blood pressure lowering medicine containing aliskiren
Before taking LOSACAR 25MG TABLET, inform your doctor if you:
- have a history of angioedema (swelling of the face, lips, throat and/or tongue)
- suffer from excessive vomiting/diarrhoea leading to extreme loss of fluid and/or salt in your body
- suffer from primary hyperaldosteronism (a syndrome associated with increased secretion of aldosterone hormone)
- suffer from cerebrovascular disease (caused by a reduced blood circulation to the brain)
- salt-restricted diet
Use in Pediatrics:
LOSACAR 25MG TABLET is not recommended for use in children under 6 years of age and also in children suffering from kidney and/or liver problems. The medicine is recommended for used in children and adolescents (aged 6 to 18 years) after consulting the doctor.
Use in Geriatrics:
LOSACAR 25MG TABLET should be used with caution in patients (aged above 75 years). Consult your doctor before taking [GBNKRYWORD].
INTERACTIONS
A. Drug-Drug Interactions:
Before taking LOSACAR 25MG TABLET, inform your doctor if you are taking any of the following medicine:
- diuretics (medicines that increase the production and excretion of urine) Ex. furosemide, bumetanide
- potassium-sparing diuretics (used as an adjunct to manage hypertension, cirrhosis and congestive heart failure) Ex. amiloride, triamterene, spironolactone
- angiotensin converting enzyme inhibitors (medicines used to treat high blood pressure Ex. enalapril, lisinopril, ramipril
- aliskiren (used to treat high blood pressure)
- beta blockers (medicine used to manage abnormal heart rhythms) Ex. atenolol, propranolol, carvedilol
- heparin (used to prevent blood clots)
- trimethoprim (used to treat urinary tract infections)
- potassium supplements and potassium-containing salt substitutes
- antidepressants (medicine used to treat depression) Ex. citalopram, fluoxetine, paroxetine
- antipsychotic drugs (used to treat mental disorders) Ex. haloperidol, thioridazine
- baclofen (medicine used for muscle spasm)
- amifostine (medicine used in cancer chemotherapy)
- non-steroidal anti-inflammatory drugs (medicines used to treat pain and inflammation) such as cox-2 inhibitors (Ex. meloxicam, etodolac), aspirin, ibuprofen
- lithium (used to treat some types of depression)
Overdosage:
If you or anyone else accidentally take too much of LOSACAR 25MG TABLET, consult your doctor immediately or visit the nearby hospital.The most common symptoms overdose are low blood pressure, fast heartbeat and slow heartbeat.
SYNOPSIS
| Drug | : | Losartan |
| Pharmacological Category | : | Angiotensin II receptor antagonists |
| Therapeutic Indication | : | Hypertension, kidney protectant, chronic heart failure, to reduce risk of stroke |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep LOSACAR 25MG TABLET out of reach of children
- Store LOSACAR 25MG TABLET below 25°C
FAQs ABOUT LOSACAR 25MG TABLET
Can LOSACAR 25MG TABLET be used to treat high blood pressure?
Yes, LOSACAR 25MG TABLET can be considered as a drug of choice to treat high blood pressure. It contains Losartan which helps to relax the blood vessels and then normalize the blood pressure. Although, LOSACAR 25MG TABLET can treat high blood pressure, you doctor might treat you with other drugs depending upon your condition.
Can LOSACAR 25MG TABLET cause slow heart rate?
Yes. LOSACAR 25MG TABLET can make your heart to beat slow. If you experience any abnormally slow heart rate with shortness of breath, feeling of fainting and spinning consult your doctor for advice.
What precautions do I need to follow while taking LOSACAR 25MG TABLET?
Patients taking LOSACAR 25MG TABLET must inform their doctor about their pre-existing disease conditions like kidney, heart or liver problems. Consult your doctor immediately if you experience any unusual symptoms after taking LOSACAR 25MG TABLET.
What are the most common side effects of taking LOSACAR 25MG TABLET?
The most common side effects of taking LOSACAR 25MG TABLET are dizziness, general weakness, tiredness, low blood sugar (associated with signs such as fast heartbeat, shaking, sweating), changes in kidney function (associated with signs such as decreased urine output, oedema, shortness of breath) and/or anaemia. Consult your doctor if any of these symptoms worsens.
Is [GBNKEYWORD] safe to use in children?
LOSACAR 25MG TABLET is not recommended for use in children under 6 years of age and also in children with kidney/liver problems. It is recommended for use in children and adolescents (aged 6-18 years) after consulting the doctor.
REFERENCES
1. KD. Tripathi. Drugs Affecting Renin-Angiotensin System and Plasma Kinins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 506
2. Sana Mulla; Waqas J. Siddiqui. Losartan. NIH National Library of Medicine. National Center for Biotechnology Information. July 2022. [Accessed on 11th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK526065/
3. Merck Sharp & Dohme Limited. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 11th May 2022]. https://www.medicines.org.uk/emc/files/pil.7799.pdf
USEFUL DIAGNOSTIC TESTS
- Blood pressure test
- Kidney function test
VIDEOS
Losartan Tablet - Drug Information
Losartan Tablet : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage
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