Lithic SR 450mg Tablet 10'S

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Drug Information for Lithic SR 450mg Tablet 10'S

What is LITHIC SR?

  • LITHIC SR contains Lithium carbonate which belongs to mood-stabilizing agents
  • It works by stabilising the levels of chemicals in your brain that affect your mood







What LITHIC SR is used for?

LITHIC SR can be used to manage or control:

  • Mania (feeling highly excited, being over-active and easily irritated or distracted)
  • Hypo-mania (similar to mania, but less severe)
  • Repeated periods of depression, where treatment with other medicines has not worked
  • Aggressive or self-harming behaviour

It is also used to help prevent bipolar depression - where the mood changes between feeling very high (mania) and very low (depression)

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Talk to your doctor before taking this medicine, if you:

  • are allergic to Lithium carbonate or to any of the ingredients in this medicine
  • have heart disease
  • have severe kidney problems
  • have an under-active thyroid gland that is not being treated
  • have are dehydrated or on a low sodium diet
  • have an illness called ‘Addison’s disease’
  • have a rare condition called Brugada syndrome
  • have a cold or flu
  • have gastroenteritis marked by diarrhoea, stomach pain, being sick, headache, fever and chills
  • have a urinary infection
  • are about to receive anaesthetics
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  • Talk to your doctor before taking this medicine if you plan to get pregnant or think you may be pregnant
  • If you find out you are pregnant while taking LITHIC SR, tell your doctor straight away
  • Do not take LITHIC SR if you are pregnant, especially in the first 3 months of your pregnancy
  • Do not breast-feed if you are taking LITHIC SR. This is because small amounts may pass into the mother’s milk
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  • LITHIC SR is not recommended for children and adolescents
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  • Do not drive or use any tools or machines if you feel sleepy, tired or dizzy. LITHIC SR may also cause other effects that can make it dangerous to drive or use tools and machines such as numbness, paralysis, weakness or fits (seizures)
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Tell your healthcare provider about all the medicines you take, including prescription, over-the-counter medicines, vitamins and herbal supplements

  • any other medicines containing lithium
  • medicines used for infections (antibiotics) - such as metronidazole, erythromycin, doxycycline or oxytetracycline
  • steroids - used for inflammation and allergies (such as prednisolone, betamethasone or hydrocortisone)
  • theophylline - used for wheezing or difficulty in breathing
  • caffeine
  • diuretics such as furosemide, chlortalidone, indapamide, spironolactone or acetazolamide
  • urea used in some creams that soften and moisturise the skin
  • aspirin, ibuprofen, indomethacin or diclofenac used to treat pain relief and swelling
  • medicines used for heart problems or high blood pressure - such as enalapril, lisinopril or ramipril (ACE inhibitors)
  • medicines used to control your heart beat - such as quinidine, disopyramide, procainamide, amiodarone and sotalol
  • losartan, candesartan, irbesartan (called ‘angiotensin II receptor antagonists’)
  • some medicines for indigestion and heartburn (antacids) - such as sodium bicarbonate and cisapride
  • calcitonin – used for hypercalcaemia and Paget’s disease/acute bone loss
  • fluvoxamine, paroxetine or fluoxetine used for depression
  • medicines used to calm emotional and mental illnesses - such as haloperidol, flupentixol, diazepam, thioridazine, or clozapine
  • methyldopa used for high blood pressure
  • some medicines used for fits (epilepsy) – such as carbamazepine or phenytoin
  • medicines used for chest pain (angina) or high blood pressure - such as diltiazem or verapamil
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  • Always take LITHIC SR exactly as your doctor has told you
  • The amount you eat and drink is very important as it can affect the levels of LITHIC SR in your blood
  • Drink the same amount of fluids every day while taking LITHIC SR. In hot environments or if you are dehydrated, you may need to drink extra fluids
  • Have a normal balanced diet while taking LITHIC SR. Do not change your diet without talking to your doctor first

How to take your medicine

  • Swallow the tablets whole. Do not crush or chew them
  • Take your medicine at the same times every day

Adults weighing about 70kg

  • The usual starting dose is between 400mg to 1,200mg each day

Elderly and adults weighing under 50kg

  • The usual starting dose is between 200mg to 400mg each day
  • Your doctor may decide to increase this dose by 200mg to 400mg every 3 to 5 days
  • Increasing the dose is usual, but do not do this unless your doctor tells you to
  • The maximum dose will depend on your blood levels and illness

If you take more LITHIC SR

  • If you or someone else has taken more LITHIC SR, talk to a doctor or go to your nearest hospital casualty department straight away
  • The following effects may happen: feeling sick or being sick, blurred vision, increased need to pass water, lack of control over passing water or stools, feeling lightheaded or drowsy, confusion and blackouts. You may also experience shaking or muscle weakness, muscle twitches and jerks or spasms causing unusual movements of the face, tongue, eyes or neck. In severe cases you may lose consciousness, have fits, shortness of breath or chest pain

If you forget to take LITHIC SR

  • If you forget to take a dose at the right time, take it as soon as you remember, then go on as before. Do not take a double dose to make up for a forgotten dose

If you stop taking LITHIC SR

  • Keep taking your medicine until your doctor tells you to stop. Do not stop taking LITHIC SR just because you feel better. If you stop, your illness may return. When your doctor says that you can stop taking LITHIC SR, your dose will be lowered gradually
  • Your doctor will help you to do this
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Like all medicines, this medicine can cause side effects, although not everybody gets them.


  • Allergic reactions may include: rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue
  • Swelling around the feet and ankles, face and stomach and weight gain due to water retention
  • Cloudy or foamy urine (water)
  • Feeling confused, dazed, delirious or loss of consciousness
  • Memory problems, fits (seizures), irregular or slow heart beats, shortness of breath, chest pain and fainting
  • Involuntary eye movements
  • Abnormal muscle breakdown (rhabdomyolysis) which can lead to kidney problems
  • Increased thirst and passing water (urine) more often than normal
  • hyperthyroidism
  • You feel tired, have cold skin and hair becomes dry, thinning of hair or fingernails, hoarse voice, joint or muscle pain and gain weight. This could be due to lower levels of thyroid hormone in the blood (hypothyroidism)
  • increased thirst, pass more water than usual, feel tired or depressed, muscle aches or pains, bone or joint pain and stomach upsets (hyperparathyroidism)
  • indigestion or heartburn, abdominal pain, black tarry stools (faeces) or blood in your stools or you may notice blood or dark bits (like coffee grounds)
  • numbness, weakness and pain in the arms and legs (peripheral neuropathy)
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Blood Tests

  • Within the first week of treatment your doctor will give you a blood test. This is to check the level of lithium in your blood
  • Your daily dose will be changed depending on the results of your blood test
  • Your doctor will carry out a blood test every week until the level of lithium in your blood is steady
  • You will then have your blood tested every 3 months to check the level remains steady
  • If you are going to have other types of blood test, tell the doctor or nurse that you are taking LITHIC SR

Tell your doctor if any of the following side effects gets serious or lasts longer than a few days:

  • hair loss or inflamed hair follicles
  • acne, skin spots or rashes, skin ulcers and/or itching
  • slight shaking of the hands
  • you have skin irritation and swelling. skin may appear red, itchy with silvery scales (psoriasis)

If you already have this condition, you could notice that it is getting worse

  • nausea, a watery or dry mouth and/or changes in the way things taste, stomach pain
  • sexual problems including being unable to get an erection, having delayed ejaculation or being unable to have an orgasm
  • blurred vision or blind spots in your eyesight
  • uncontrolled movements of the eye
  • weight gain
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  • Keep this medicine out of reach of children
  • Store at room temperature (15-25°C)
  • Do not use this medicine after the expiry date
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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