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Intas Pharmaceuticals Ltd

Levera Injection 5ml

Epilepsy/Convulsion
Revised GST MRP ₹106.31 17.5% OFF 17.5% OFF (Inclusive of all taxes)
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    Introduction About LEVERA INJECTION

    LEVERA INJECTION is used in the management of epilepsy (seizures). It contains a medicine called Levetiracetam which is an Anticonvulsant that works by modifying the release of certain brain chemicals that causes seizure breakouts.

    LEVERA INJECTION is also used in combination with other antiepileptic medicines to manage partial onset seizures, myoclonic seizures, juvenile myoclonic epilepsy, primary generalized tonic-clonic seizures and idiopathic generalized epilepsy.

    Before taking this medicine, inform your doctor if you have liver, kidney, or heart diseases. This medicine should be used with caution in pregnant women and not recommended for use in breast-feeding women.

    The most common side effects of taking LEVERA INJECTION are inflammation of the nose and throat, sleepiness, dizziness, laziness, lack of hunger, depression, anxiety, vertigo, cough, and nausea.

    Studies have shown that levetiracetam may cause some serious side effects like suicidal thoughts with severe depression. Patient’s caregivers must notice for any such side effects and inform doctor immediately.

    Uses Of LEVERA INJECTION

    How LEVERA INJECTION Works

    Levetiracetam works by reducing abnormal electrical activity in the brain to help control seizures. It binds to a protein called synaptic vesicle protein 2A (SV2A), which is involved in the release of neurotransmitters (chemical messengers) between nerve cells. By modifying this process, levetiracetam helps stabilize brain activity and prevent seizures.

    How to use LEVERA INJECTION

    • LEVERA INJECTION is typically administered in a hospital or clinical setting by a healthcare professional
    • It is given as an intravenous (IV) infusion directly into a vein
    • The dosage and administration depend on the patient’s condition, age, and weight, as well as how they respond to the treatment

    Side Effects Of LEVERA INJECTION

    Common side effects of LEVERA INJECTION:

    • inflammation of the nose and throat, respiratory problems, cough
    • somnolence, headache
    • depression, aggression, anxiety, insomnia, nervousness, irritability
    • balance disorder
    • dizziness, tiredness
    • tremor (involuntary trembling), forgetfulness,
    • vertigo (sensation of rotation or spinning)
    • abdominal pain, diarrhoea, indigestion, vomiting, nausea, loss of appetite
    • changes in body weight
    • tingling and numbness
    • hair loss

    Stop taking this medicine and inform your doctor immediately if you experience any of the following side effects:

    • signs of sudden decrease of kidney function (low urine volume, tiredness, nausea, vomiting, confusion, and swelling in the legs, ankles, or feet)
    • signs of serious mental changes that can be symptoms of encephalopathy (confusion, sleepiness, loss of memory, forgetfulness, abnormal behaviour, involuntary or uncontrolled movements)
    • abnormal thoughts, feeling irritable, or reacting more aggressively
    • aggravation (worsening) of epilepsy

     

     

    Warning & Precautions

    Pregnancy

    Monitoring required

    LEVERA INJECTION should be used with caution in pregnant women only if considered clearly necessary by the doctor.

    Breastfeeding

    Contraindicated

    It is not recommended for use in breastfeeding women due to increased risk of side effects.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any machines if you feel sleepy after taking this medicine.

    Alcohol

    Consult your doctor

    Avoid the consumption of alcohol while taking this medicine.

    Kidney

    Use with Caution

    LEVERA INJECTION should be used with caution in patients with kidney disease.

    Allergy

    Contraindicated

    Do not take this medicine if you are allergic to levetiracetam or to any other ingredients of this medicine.

    Heart Disease

    Use with Caution

    It should be used with caution in patients with heart diseases such as family or medical history of irregular heart rhythm (visible on an electrocardiogram) or if you are prone to heartbeat irregularities.

    Use In Pediatrics

    Consult your doctor

    It is not recommended for use in children and adolescents under 16 years of age if used alone. However, it can be used in children and adolescents in combination with other medicines. Your doctor will prescribe the right dose depending on your child’s age, body weight, and disease condition.

    Use In Geriatrics

    Use with Caution

    LEVERA INJECTION should be used with caution in elderly patients. Follow the dosing instructions mentioned by your doctor.

    Others

    Before taking this medicine, tell your doctor if you:

    • have salt imbalance

    Interactions

    A. Drug-Drug Interactions:

    Inform your physician if you are taking any of the following medicines before taking LEVERA INJECTION:

    • laxative such as macrogol (used to manage constipation)

    Overdosage:

    If you or anyone else accidentally took an extra dose of this medicine, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are sleepiness, aggression, agitation, inhibition of breathing, and decrease of alertness.

    Synopsis

    Drug :   Levetiracetam
    Pharmacological Category :   Anticonvulsants
    Therapeutic Indication :   Epilepsy            
    Dosage Forms :   Tablet, Injection, Infusion, Syrup, Suspension, Oral Suspension, Solution

    More Information

     

     

    FAQs About LEVERA INJECTION

    Q: What is LEVERA INJECTION used for?

    A: LEVERA INJECTION is used to manage epilepsy (seizures).

    Q: How long can you take LEVERA INJECTION?

    A: LEVERA INJECTION can be taken as advised by your doctor. The dose and duration depend on the type of epilepsy and its severity. It should not be stopped until your doctor advises.

    Q: What is the half-life of LEVERA INJECTION?

    A: The half-life of LEVERA INJECTION depends on various factors such as age, kidney function, and overall health. However, in healthy adults, the typical half-life of levetiracetam is about 6 to 8 hours.

    Q: What is the difference between LEVERA INJECTION and levetiracetam?

    A: Levetiracetam is the generic name of the drug which is the active ingredient used to manage epilepsy (seizures).

    [GBNKEWORD] is a brand name version of levetiracetam. In this case, Levipil 500 contains 500 mg of levetiracetam.

    Q: Is LEVERA INJECTION a high-risk medicine?

    A: LEVERA INJECTION is not generally considered a high-risk medicine in most cases. But like any medication it carries certain risks especially if not used properly or monitored.

    Q: Does LEVERA INJECTION cause sleep?

    A: Yes. LEVERA INJECTION can cause drowsiness or sleepiness.

    Q: Does memory come back after a seizure?

    A: Yes. Memory recovery after a seizure can vary widely from person to person and depends on several factors such as type of seizure, its severity, and the specific brain regions involved.

    Q: What is the best time of day to take levetiracetam?

    A: Always take Levetiracetam as advised by your doctor. Consult your doctor for advice before taking this medicine.

    Q: What are the major side effects of levetiracetam?

    A: The major side effects of taking levetiracetam are inflammation of the nose and throat, sleepiness, dizziness, lethargy, anorexia, depression, anxiety, vertigo, cough, and nausea. Contact your doctor if you experience these above side effects or worsen.

    Q: Does levetiracetam stop seizures completely?

    A: Yes. It can be stopping seizures completely.

    Q: Is levetiracetam a good medication?

    A: Yes. Levetiracetam is a good choice of medication for epilepsy (seizures).

    Q: What is the age limit for levetiracetam?

    A: Levetiracetam can be used for both adults and children. But the age limit for its use depends on the type of seizures.

    References

    1. K.D. Tripathi. Antiepileptic Drugs. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 420.

    2. Bassel Abou-Khalil. Levetiracetam in the treatment of epilepsy. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. June 2008. [Accessed on 20th Sept 2024] click here

    3. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in June 2023] [Accessed on 20th Sept 2024] click here

    4. Sun Pharmaceutical Industries. Electronic Medicines Compendium (EMC). [Revised in May 2022]. [Accessed on 7th October 2024] click here

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)
    Last updated on 21 Nov 2024 | 12:46 PM(IST)
    Lab updated