LETRO EN 2.5 Tablet 5's

Cancer/Oncology Rx required
OUT OF STOCK

Best Price*  ₹ 95.20
MRP ₹119.00
(Inclusive of all taxes) *5 Tablet(s) in a Strip * Mkt: ENITIO HEALTHCARE PVT LTD * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

LETRO EN 2.5 contains Letrozole which belongs to the group of medicines called Hormonal Chemotherapeutic agents. It is used to treat and prevent breast cancer in postmenopausal women. It can be given either as an initial therapy or following therapy with other medicines such as tamoxifen. It can also be used to prevent breast tumor from spreading to other parts of the body in patients with advanced breast cancer.

Breast cancer can be defined as the uncontrollable growth and division of cells present in the breast. It is predominantly caused due to hormonal imbalance (increased estrogen production) or due to lifestyle factors. Symptoms include breast pain or tenderness, purple or red colored breasts, nipple discharge and lump growths.

Letrozole is an aromatase inhibitor. It reduces breast cancer by suppressing the excessive release of estrogen (a female sex hormone) in the body that triggers breast cancer. This slows down or stops the cancer from growing and spreading to other parts of the body. Before taking LETRO EN 2.5 inform your doctor if you have any problems in your kidneys or liver. You must also inform your doctor before taking LETRO EN 2.5 if you have a history of any bone problems such as osteoporosis or joint pain.

LETRO EN 2.5 is only intended for use in women who have reached their menopause. It is strictly not recommended for use in pregnant women as it may cause serious harm to the growing baby. The most common side effects of taking LETRO EN 2.5 are hot flushes, fatigue, increased sweating, joint pain, hair loss, vaginal bleeding, and high blood cholesterol levels. Talk to your doctor if any of these side effect bothers you.

USES OF LETRO EN 2.5

  • Treats and prevents breast cancer in postmenopausal women

HOW LETRO EN 2.5 WORKS

LETRO EN 2.5 is a hormonal chemotherapy medicine. It contains letrozole which is an aromatase inhibitor. It acts by blocking the actions of an enzyme called aromatase in the body which is involved in the production of estrogen (a female sex hormone). This suppresses the release of excessive estrogen in the body that triggers breast cancer. As a result, it slows down or stops the cancer from growing and spreading to other parts of the body.

DIRECTIONS FOR USE

Take LETRO EN 2.5 as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. LETRO EN 2.5 can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Continue to take LETRO EN 2.5 for the stipulated duration instructed by your doctor to achieve better results.

SIDE EFFECTS OF LETRO EN 2.5

COMMON

  • hot flushes
  • feeling weak or tired
  • increased sweating
  • joint pain, muscle pain
  • skin rash
  • headache, dizziness
  • nausea, vomiting, indigestion, constipation, diarrhoea, loss of appetite, stomach pain
  • swelling of arms, hands, feet, ankles, weight gain
  • depression
  • hair loss, dry skin
  • vaginal bleeding
  • palpitations (rapid heartbeat)
  • high blood cholesterol levels

UNCOMMON

  • feeling anxious, nervous or irritated
  • drowsiness
  • memory problems, insomnia (lack of sleep)
  • pain or burning sensation in the hands or wrist (carpal tunnel syndrome)
  • impaired sensation of touch, tingling or numbness
  • vaginal discharge or dryness
  • breast pain
  • thirst, taste disorder, dry mouth
  • weight loss
  • urinary tract infection, increased frequency of urination
  • cough
  • inflammation of the mouth and lips (stomatitis)

RARE

Stop taking LETRO EN 2.5 and contact your doctor immediately if you experience any of the following side effects:

  • signs of blood clot in the body (such as difficulty in breathing, fainting, rapid heart rate, chest pain, bluish skin discoloration, leg, or foot pain)
  • tendon rupture causing bone pain, inflammation of the tendons
  • severe persistent blurred vision
  • severe fever, chills, or mouth ulcers due to infections
  • swelling and redness along a vein which is tender painful when touched
  • sudden onset of oppressive chest pain
  • signs of a brain disorder or a stroke (such as weakness, paralysis, or numbness in any part of the body, loss of coordination, nausea, or difficulty in speaking or breathing)
  • signs of allergic reactions (such as swelling of the face and throat)
  • hepatitis (symptoms include loss of appetite, dark-colored urine, yellow skin and eyes, nausea)
  • signs of serious skin reactions (such as skin rash, red skin, blistering and peeling of the skin, accompanied with fever)

HOW TO MANAGE SIDE EFFECTS

Skin rash:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.

WARNING & PRECAUTIONS

PREGNANCY

LETRO EN 2.5 is intended for use in postmenopausal women. It should not be used by pregnant women as it may cause serious harm to the growing baby. Women who are in pre-menopause or has childbearing potential should use a suitable contraceptive method to prevent pregnancy while taking LETRO EN 2.5.

BREASTFEEDING

LETRO EN 2.5 is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy, tired, drowsy or generally unwell after taking LETRO EN 2.5.

ALCOHOL

Avoid consumption of alcohol while taking LETRO EN 2.5 to avoid unwanted reactions.

KIDNEY

LETRO EN 2.5 should be used with caution in patients with severe kidney diseases. Therefore, consult your doctor before taking it.

LIVER

LETRO EN 2.5 should be used with caution in patients with severe liver diseases. Therefore, consult your doctor before taking it.

ALLERGY

Do not take LETRO EN 2.5 if you are allergic to letrozole.

OTHERS

LETRO EN 2.5 is not recommended for use if you:

  • still have periods i.e., have not gone through menopause

Before taking LETRO EN 2.5, inform your doctor if you have:

  • a history of bone fractures or osteoporosis
  • osteoporosis (weak bones) or joint inflammation

Use in Pediatrics:

LETRO EN 2.5 is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

Use in Geriatrics:

LETRO EN 2.5 should be used with caution in elderly patients (aged 65 years or older). Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug - Drug interactions:

Before taking LETRO EN 2.5 inform your doctor if you are taking any of the following medicines such as:

  • other medicines used to treat cancer (Ex. tamoxifen, anastrozole)
  • cimetidine (a medicine used to treat stomach ulcer)
  • warfarin (a medicine used for blood thinning)

Over dosage:

If you or anyone else accidentally took more LETRO EN 2.5, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug :   Letrozole
Pharmacological Category :   Aromatase inhibitor
Therapeutic Indication :   Breast cancer in postmenopausal women
Dosage Forms :   Tablet, Capsule

MORE INFORMATION

  • Keep LETRO EN 2.5 out of reach of children
  • Store LETRO EN 2.5 at room temperature

FAQs ABOUT LETRO EN 2.5

How does LETRO EN 2.5 works?

LETRO EN 2.5 is a hormonal chemotherapy medicine. It contains letrozole which is an aromatase inhibitor. It acts by blocking the actions of an enzyme called aromatase in the body which is involved in the production of estrogen (a female sex hormone). This suppresses the release of excessive estrogen in the body that triggers breast cancer. As a result, it slows down or stops the cancer from growing and spreading to other parts of the body.

Can I take LETRO EN 2.5 during breastfeeding?

No. LETRO EN 2.5 is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking.

Can LETRO EN 2.5 cause headache?

Yes. LETRO EN 2.5 may cause headache in some individuals. If you experience headache, rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume alcohol. Consult your doctor if your headache worsens.

Can LETRO EN 2.5 increase the risk of infections?

LETRO EN 2.5 may cause a drop in the number of white blood cells in the body and may weaken your immune system. As a result, you may be at greater risk of getting infected while taking LETRO EN 2.5. To avoid this, your doctor will regular monitor your blood counts as a precaution. However, inform your doctor if you experience any signs of infection such as fever.

Can the use of LETRO EN 2.5 make me feel tired?

Yes. LETRO EN 2.5 may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anaemic. Consult your doctor if you experience tiredness after taking LETRO EN 2.5. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while taking this medicine.

Can I drive a car after taking LETRO EN 2.5?

LETRO EN 2.5 may make you feel tired, dizzy, or drowsy. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by LETRO EN 2.5.

How to take LETRO EN 2.5?

Take LETRO EN 2.5 as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. LETRO EN 2.5 can be taken with or without food.

What should I do if I forget to take a dose of LETRO EN 2.5?

If you forget to take a dose of LETRO EN 2.5, or vomited immediately after taking the dose, take it as soon as you remember. Do not take the medicine twice to make up for the forgotten dose.

How to control nausea caused due to LETRO EN 2.5?

Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with LETRO EN 2.5. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.

REFERENCES

1. K.D. Tripathi, Essentials of medical pharmacology, Primary and secondary prevention of breast cancer. Chapter - Hormones and related drugs. Seventh Edition. 2013. Page – 314.

2. Dong-xu He Xin Ma, Clinical utility of letrozole in the treatment of breast cancer: a Chinese perspective. Onco Targets and Therapies. March 2016. [Accessed on 20th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780194/pdf/ott-9-1077.pdf

3. Ajay S. Bhatnagar. The discovery and mechanism of action of letrozole. NIH: National Library of Medicine, National Center for Biotechnology Information. PMC, PubMed Central. 3 Oct 2007. [Accessed 20 May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001216/

4. Accord Healthcare Ltd. Electronic Medicines Compendium (EMC). [Revised in Jan 2020] [Accessed 20 May 2022] https://www.medicines.org.uk/emc/files/pil.6054.pdf

USEFUL DIAGNOSTIC TESTS

  • Breast Cancer (CA 15.3/ ER/ PR)

PRODUCT DETAILS

    Country Of Origin
    India
ALTERNATE BRANDS View All
LETROTRU 2.5 Tablet 5's
Prescription Cancer/Oncology Rx required
Rs.90.00
LETSURE 2.5 Tablet 5's
Prescription Cancer/Oncology Rx required
Rs.138.00
LETZOL 2.5 Tablet 5's
Prescription Cancer/Oncology Rx required
Rs.154.00
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Copyright© 2022. All Rights Reserved.