KZ contains Ketoconazole which belongs to the group of medicines called antifungals. It is used to treat infections such as athlete's foot, jock itch, ringworm, and seborrhea (dry, flaking skin or dandruff). This medicine works by binding to the fungal p450 enzymes and stops the cells making ergosterol of the cell wall which is necessary for them to grow.
Apply the medicine onto to the affected area or as directed by physician. It is for external use only. It is recommended for the use in children and adolescents. Do not take this medicine, if you have eye infections. It should be used in pregnant or breastfeeding women, consult your doctor before taking this medicine. Tell your doctor if you are using any of the other topical medicines. The most common side effects include burning sensation, irritation and reddening of the skin.
KZ binds to the fungal p450 enzymes and stops the cells making ergosterol of the cell wall which is necessary for them to grow.
Apply the medicine onto the affected area or as directed by physician. It is for external use only.
Skin irritation:
Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.
KZ is considered safe for use by pregnant women. It is advised to consult your doctor before taking this medicine.
KZ is safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine.
Do not take if you are allergic to the medicine.
Tell your doctor if you are using any other cream, ointment or lotion on your skin infection that contains a steroids.
Drug | : | Ketoconazole |
Pharmacological Category | : | Antifungal |
Therapeutic Indication | : | Treat fungal infection |
Dosage Forms | : | Tablet, Cream, Gel, Ointment, Lotion, Soap, Dusting powder |
Store at room temperature 15-25°C and keep out of reach of children.
Can KZ be used in pregnant women?
Yes. It is safe for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
How does KZ kill fungus?
It kills fungi by binding to the fungal p450 enzymes and stops the cells making ergosterol of the cell wall.
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2. Jan van cutsem; The antifungal activity of ketoconazole; [Revised on Jan 1983] [Accessed 11 Dec 2020] https://www.amjmed.com/article/0002-9343(83)90508-9/fulltext
3. K.D.Tripathi, Essentials of medical pharmacology, ANTIMICROBIAL DRUGS, Chapter 57 – ANTIFUNGAL DRUGS, 7th edition 2013, Page – 792.
4. Glenmark Pharmaceuticals s.r.o., U.S. Food and Drug Administration; [Revised on July 2013] [Accessed 11 Dec 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf
5. Janssen Pharmaceutica NV; Electronic Medicines Compendium (EMC); [Revised on Mar 2019] [Accessed 11 Dec 2020] https://www.medicines.org.uk/emc/files/pil.970.pdf
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