KUTUB 30 X Tablet 4's
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Introduction About KUTUB 30 X TABLET
KUTUB 30 X TABLET is a combination of Dapoxetine and Sildenafil, which belong to the group of medicines called Selective serotonin reuptake inhibitors and Phosphodiesterase type 5 (PDE5) inhibitors, respectively. It is used in adult men to help improve blood flow to the penis and to manage early ejaculation by balancing certain chemicals in the brain.
Before taking KUTUB 30 X TABLET, inform your doctor if you have any previous history of fainting or dizziness due to low blood pressure. You must also inform your doctor if you have epilepsy, lung problems, mental health problems, or bleeding disorders before taking KUTUB 30 X TABLET as a precaution. KUTUB 30 X TABLET is not recommended for use in patients with liver or heart problems. Avoid taking KUTUB 30 X TABLET with heavy meals or with grapefruit juice.
The most common side effects of taking KUTUB 30 X TABLET are flushing, headache, dizziness, blurred vision, muscle pain, nausea, tiredness, increased sweating, restlessness, and a decrease in sex drive. Consult your doctor if any of these side effects trouble you.
Also, inform your doctor immediately if you experience any prolonged painful penile erections without sexual stimulation (priapism), experience dizziness upon standing up suddenly, or if you have sudden mood changes or suicidal thoughts after taking KUTUB 30 X TABLET.
Uses Of KUTUB 30 X TABLET
It is used by adult men to:
- Help improve blood flow to the penis
- Manage early ejaculation
How KUTUB 30 X TABLET Works
KUTUB 30 X TABLET contains two medicines called dapoxetine and sildenafil. Dapoxetine delays ejaculation by blocking the reuptake of a chemical messenger called serotonin between the nerve cells. This increases the activity of serotonin within the brain, which therefore increases the time taken to release the semen (ejaculate) during sexual intercourse.
Sildenafil works by improving the blood supply to the penis. It works by blocking the effects of certain enzymes (PDE5) in the body that limit blood flow to the penis. As a result, it relaxes the blood vessels supplying the penis and improves blood flow.
How to use KUTUB 30 X TABLET
Take KUTUB 30 X TABLET as advised by your physician. Swallow KUTUB 30 X TABLET with a glass of water. Do not chew or crush the medicine. Take KUTUB 30 X TABLET, preferably before meals, and at least 30 minutes to 1 hour before planning to have sexual intercourse. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and health condition.
Side Effects Of KUTUB 30 X TABLET
Common
- dizziness, headache
- nausea, vomiting
- feeling irritable, anxious, agitated, or restless
- sensation of numbness, tingling or prickling
- increased sweating
- hot flushes
- diarrhea, constipation, wind, and stomach pain
- problems in sleeping or strange dreams, difficulty in concentration
- tiredness or sleepiness
- blocked nose
- a rise in blood pressure
- decrease in sex drive
- ringing in the ears
- blurred vision, color tinge to vision, visual disturbance
- dry mouth
Uncommon
- fainting
- change in mood, feeling overly excited or feelings of paranoia (feeling threatened)
- feeling confused, disoriented, or unable to think clearly
- abnormal heartbeat (slow or fast heart rate)
- feeling depressed or nervous
- feeling hot, jittery, abnormal, or drunk
- eye problems (eye irritation, pain or redness, watery eyes, double vision, abnormal sensation in the eye, seeing light flashes)
- low blood pressure
- feeling itchy or cold sweats
- spinning sensation
- abnormal taste
- skin rash
- muscle pain
- reduced sense of touch
- signs of inflammation of the lining of the nose, such as a runny nose or sneezing
- upper abdominal pain
- signs of gastroesophageal reflux disease, such as heartburn
- presence of blood in urine or semen
- pain in the arms or legs
- nosebleed
Rare
- penile bleeding
- dry nose
- throat tightness, numbness of the mouth
- temporary decrease in blood flow to the brain
- sudden decrease or loss of hearing
- sudden onset of sleep (Ex. narcolepsy)
- urge to empty the bowel
Stop taking KUTUB 30 X TABLET and contact your doctor if you experience any of the following side effects:
- severe allergic reaction (such as wheeziness, difficulty breathing or dizziness, swelling of the face, lips, eyelids, or throat)
- prolonged or painful erection (priapism)
- chest pain, especially during or after sexual intercourse
- severe skin reactions (blistering of skin around the mouth, genitals or eyes, severe peeling and swelling of skin along with fever)
- sudden decline or loss of vision
- fits or seizures
- fainting or lightheadedness while standing
- mood changes, suicidal thoughts, or a tendency for self-harming
How To Manage Side Effects
Diarrhea
Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens or if you feel dizzy upon standing up suddenly.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids, such as water or electrolytes. Applying a pain-relieving balm to your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take KUTUB 30 X TABLET with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Consult your doctor if your vomiting worsens.
Warning & Precautions
Pregnancy
ContraindicatedKUTUB 30 X TABLET is not intended for use by women.
Breastfeeding
ContraindicatedKUTUB 30 X TABLET is not intended for use by women.
Driving and Using Machines
ContraindicatedDo not drive or operate any machines if you experience dizziness or blurred vision after taking KUTUB 30 X TABLET.
Alcohol
ContraindicatedAvoid consumption of alcohol while taking KUTUB 30 X TABLET, as it may cause dizziness or sleepiness.
Kidney
Use with CautionKUTUB 30 X TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
Liver
ContraindicatedKUTUB 30 X TABLET is not recommended for use in patients with moderate or severe liver diseases. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take KUTUB 30 X TABLET if you are allergic to Dapoxetine or Sildenafil.
Lungs
Use with CautionKUTUB 30 X TABLET should be used with caution in patients with pulmonary arterial hypertension. Therefore, consult your doctor before taking it.
Heart Disease
ContraindicatedKUTUB 30 X TABLET is not recommended for use in patients with heart problems (such as heart failure, low blood pressure, or problems with the heart rhythm). Therefore, consult your doctor before taking it.
Use In Pediatrics
ContraindicatedKUTUB 30 X TABLET is not recommended for use in children and adolescents (below 18 years). Therefore, consult your doctor before taking it.
Use In Geriatrics
ContraindicatedKUTUB 30 X TABLET is not recommended for use in elderly patients (aged 65 years or older). Therefore, consult your doctor before taking it.
Others
KUTUB 30 X TABLET is not recommended for use if you:
- have a history of fainting
- have or ever had signs of mania, such as feeling overexcited, irritable, or not being able to think clearly
- have severe depression
- have recently had a stroke
- have low blood pressure
- have signs of retinitis pigmentosa (rare inherited eye disease) such as decreased vision at night or in low light and loss of side vision
Before taking KUTUB 30 X TABLET, inform your doctor if you:
- have a history of feeling dizzy due to low blood pressure
- have schizophrenia (a psychiatric disease)
- have epilepsy
- have a history of bleeding or blood clotting problems
- have or are at risk of developing glaucoma
- have sickle cell anemia (an abnormality of red blood cells)
- have leukemia (cancer of blood cells)
- have multiple myeloma (cancer of the bone marrow)
- have a deformity in your penis
- have Peyronie’s disease (the development of fibrous scar tissue in the penis that causes painful erection)
- currently have a stomach ulcer
- have bleeding problems such as hemophilia
- are alcoholic
Interactions
A. Drug-Drug Interactions:
Before taking KUTUB 30 X TABLET, inform your doctor if you are taking any of the following medicines, such as:
- nitrates or amyl nitrites (used for reliving chest pain) Ex. nitroglycerin, isosorbide dinitrite
- other medicines used to manage prostate problems or blood pressure, such as alpha blockers (Ex. silodosin, doxazosin)
- riociguat (a medicine used to manage increased pressure in the lungs)
- medicines used to manage depression (Ex. fluoxetine, sertraline, citalopram, escitalopram, amitriptyline, isocarboxazid, selegiline, nefazodone and St. john’s wort)
- thioridazine (a medicine used to manage a mental disorder called schizophrenia)
- lithium (a medicine used to manage bipolar disorder)
- tryptophan (a medicine used to induce sleep)
- medicines used to manage migraines (Ex. almotriptan, sumatriptan)
- non-steroidal anti-inflammatory drugs (used to manage pain and inflammation) Ex. ibuprofen and aspirin
- tramadol (a medicine used to relieve pain)
- antibiotics (used to manage bacterial infections) Ex. telithromycin, linezolid, erythromycin, and clarithromycin
- medicines used to manage HIV infection (Ex. ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir and fosamprenavir)
- medicines used to manage fungal infections (such as ketoconazole, itraconazole and fluconazole)
- warfarin (a medicine used to manage blood clotting)
- other medicines used to manage erectile dysfunction (such as tadalafil or vardenafil)
- medicines used to manage high blood pressure or chest pain (such as verapamil and diltiazem)
- aprepitant (a medicine that is used to manage nausea)
- medicines used to reduce anxiety and alter mental stability (Ex. morphine, pethidine, alprazolam, midazolam, clonazepam, MDMA (ecstasy) or lysergic acid diethylamide)
B. Drug-Food Interactions:
Avoid drinking grapefruit juice within 24 hours prior to taking KUTUB 30 X TABLET, as it may increase the level of KUTUB 30 X TABLET in the body. Also, taking KUTUB 30 X TABLET with a heavy meal may delay its onset of action.
Overdosage:
If you or anyone else accidentally took more KUTUB 30 X TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of an overdose are nausea and vomiting.
Synopsis
| Drug | : | Dapoxetine, Sildenafil |
| Pharmacological Category | : |
Selective serotonin reuptake inhibitors (SSRI), Phosphodiesterase type 5 inhibitors |
| Therapeutic Indication | : | Problems in erection, to manage early ejaculation |
| Dosage Forms | : | Tablet |
More Information
- Keep KUTUB 30 X TABLET out of reach of children
- Store KUTUB 30 X TABLET at room temperature
FAQs About KUTUB 30 X TABLET
Q: What is KUTUB 30 X TABLET used for?
A: KUTUB 30 X TABLET is used in adult men to help improve blood flow to the penis and to manage early ejaculation by balancing certain chemicals in the brain.
Q: How do I take KUTUB 30 X TABLET?
A: Take KUTUB 30 X TABLET at least 30 minutes to 1 hour before sexual intercourse. It should be taken, preferably before meals, for a faster onset of action. Avoid taking KUTUB 30 X TABLET with heavy meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Q: Can I take KUTUB 30 X TABLET daily?
A: KUTUB 30 X TABLET is generally prescribed as one dose per day. However, your doctor will decide whether you can take this medicine daily or not, depending upon your health condition. Do not take KUTUB 30 X TABLET more than once a day without consulting your doctor.
Q: How long does it take for KUTUB 30 X TABLET to start working?
A: It may take around 30 minutes to 1 hour for KUTUB 30 X TABLET to start working; therefore, take this medicine at least one hour before planning to have sex. This time may vary from person to person depending on their health condition. Avoid taking heavy meals while taking KUTUB 30 X TABLET, as it could further delay the onset of action.
Q: Who can take KUTUB 30 X TABLET?
A: KUTUB 30 X TABLET can be used for adult men with sexual problems. It is not suitable for use in healthy men who do not have any sexual problems or in men who are not sexually stimulated. It is also not advisable for use in children or adolescents (aged below 18 years).
Q: What happens if I consume a higher dose of KUTUB 30 X TABLET than prescribed by my doctor?
A: Do not consume a higher dose of KUTUB 30 X TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose does not help you, contact your doctor.
Q: Can men be taking KUTUB 30 X TABLET father a child?
A: There is no confirmed proof that KUTUB 30 X TABLET could affect fertility in men. However, it is better to consult your doctor before taking KUTUB 30 X TABLET if you are planning to father a child.
Q: Is KUTUB 30 X TABLET safe?
A: Yes. KUTUB 30 X TABLET is safe to use. But inform your doctor immediately if you experience painful, prolonged erections or chest pain after taking KUTUB 30 X TABLET. It can also cause headache, dizziness, flushing or muscle pain in some individuals. Contact your doctor if they bother you.
Q: Can I consume alcohol while taking KUTUB 30 X TABLET?
A: Avoid consumption of alcohol while taking KUTUB 30 X TABLET, as it could reduce the effectiveness of KUTUB 30 X TABLET.
Q: How long do the effects of KUTUB 30 X TABLET last?
A: The effects of KUTUB 30 X TABLET would normally last for 4 hours. However, this time may vary from person to person depending on their age and health condition. Consult your doctor if the effects of KUTUB 30 X TABLET do not last long.
Q: Can KUTUB 30 X TABLET make you last longer?
A: Yes. KUTUB 30 X TABLET delays the release of sperm (ejaculation) in patients suffering from premature ejaculation.
Q: Will taking KUTUB 30 X TABLET affect my sexual life?
A: Long-term use of KUTUB 30 X TABLET may negatively impact your sexual life. It may cause sexual problems, such as a decrease in sex drive. Talk to your doctor if you are facing any sexual problems while taking KUTUB 30 X TABLET.
Q: How does KUTUB 30 X TABLET work?
A: KUTUB 30 X TABLET contains two medicines called dapoxetine and sildenafil. Dapoxetine delays ejaculation by blocking the reuptake of a chemical messenger called serotonin between the nerve cells. This increases the activity of serotonin within the brain, which therefore increases the time taken to release the semen (ejaculate) during sexual intercourse.
Sildenafil works by improving the blood supply to the penis. It works by blocking the effects of certain enzymes (PDE5) in the body that limit blood flow to the penis. As a result, it relaxes the blood vessels supplying the penis and improves blood flow.
Q: Can I stop taking KUTUB 30 X TABLET on my own without consulting a doctor?
A: Do not stop taking KUTUB 30 X TABLET without consulting your physician, as sudden discontinuation of KUTUB 30 X TABLET may cause withdrawal symptoms like sleeping problems or dizziness.
Q: Can KUTUB 30 X TABLET cause bipolar disorder?
A: KUTUB 30 X TABLET may cause mood changes in some individuals. Inform your doctor immediately if you experience any sudden changes in mood. Also, it is important to inform you doctor if you already have bipolar disorder as a precaution before starting management with KUTUB 30 X TABLET.
References
1. KD. Tripathi. Drugs Used in Mental Illness: Antidepressant and Antianxiety Drugs & Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 303 & 464.
2. Murat Tukan, Mehmet Gokhan Culha and Ege Can Serefoglu. Efficacy and safety of dapoxetine/sildenafil combination tablets in the treatment of men with premature ejaculation and concomitant erectile dysfunction—DAP-SPEED Study. ResearchGate. March 2019. [Accessed on 3rd June 2022]. https://www.researchgate.net/publication/330766365_Efficacy_and_safety_of_dapoxetinesildenafil_combination_tablets_in_the_treatment_of_men_with_premature_ejaculation_and_concomitant_erectile_dysfunction-DAP-SPEED_Study
3. Menarini - Von Heyden GmbH. Electronic medicines compendium (EMC). [Revised in June 2021] [Accessed on 3rd June 2022]. https://www.medicines.org.uk/emc/files/pil.1269.pdf
4. Pharmadox Healthcare Ltd. Electronic medicines compendium (EMC). [Revised in December 2021] [Accessed on 3rd June 2022]. https://www.medicines.org.uk/emc/files/pil.13551.pdf
5. DA SUTRA 30X TABLET. Hetero Healthcare. Limited. [Accessed on 3rd June 2022]. https://www.heterohealthcare.com/da-sutra-30x-tablet
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