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Drug Information

What is Metformin + Saxagliptin combination used for?

Metformin + Saxagliptin combination is used for the treatment of diabetes. It is used in conjunction with diet and exercise for effective glycaemic control.

Metformin + Saxagliptin combination may also be prescribed for other conditions as determined by the doctor.

How does Metformin + Saxagliptin combination work?

In Metformin + Saxagliptin combination, Metformin belongs to the class of drugs called anti-diabetic drugs. This drug acts by inhibiting hepatic glucose production, which reduces blood sugar levels.

Saxagliptin belongs to the class of drugs called as anti-diabetic drugs. This drug acts by regulating the levels of glucose produced by the body after consuming food.

How to take Metformin + Saxagliptin combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Metformin + Saxagliptin combination as prescribed by your doctor.

Swallow the tablet whole. Do not crush or chew the tablet. Take the drug with or without food. However, taking the drug with food prevents stomach upset.

If you miss a dose of Metformin + Saxagliptin combination, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the drugs that interact with Metformin + Saxagliptin combination?

Drugs that interact with Metformin + Saxagliptin combination include the following:

  • Acetaminophen
  • Aspirin
  • Bexarotene
  • Cetirizine
  • Diatrizoate
  • Gatifloxacin
  • Hydrocortisone
  • Iodipamide
  • Iothalamate
  • Somatropin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Metformin + Saxagliptin combination?

The following are the most common side effects of Metformin + Saxagliptin combination:

  • Muscle aches
  • Itching
  • Weakness
  • Pain around eyes and cheek bones

The following are the severe side effects and you may require immediate medical attention:

  • Bladder pain
  • Anxiety
  • Chills
  • Blurred vision
  • Depression
  • Seizures
  • Sore throat

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Metformin + Saxagliptin combination?

  • Avoid using the medicine if you are allergic to Metformin + Saxagliptin combination or similar drugs.
  • Do not stop using the medication abruptly unless instructed by the doctor. Discontinuing the medication suddenly may cause the illness to return.
  • Do not exceed the dose more than what is prescribed.
  • Consult the doctor before taking any other drug along with Metformin + Saxagliptin combination.

You are advised not to take Metformin + Saxagliptin combination if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Metformin + Saxagliptin?

  • Tell your doctor if you have any history of type 1 diabetes, kidney and liver diseases.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Notify the doctor if you are pregnant or breastfeeding.

Frequently asked questions about Metformin + Saxagliptin

  1. What are the overdose symptoms of Metformin + Saxagliptin combination?
  2. Overdose symptoms of Metformin + Saxagliptin combination include weakness, slow heart rate, cold feeling, muscle pain, shortness of breath, seizures, tremor and confusion.

  3. Can I consume alcohol while taking Metformin + Saxagliptin combination?
  4. It is not recommended to consume alcohol while taking Metformin + Saxagliptin combination as it decreases blood sugar levels and may increase the risk of lactic acidosis.

  5. How should Metformin + Saxagliptin combination be stored?
  6. Metformin + Saxagliptin combination must be stored at room temperature, away from sunlight.

  7. Should I follow any special dietary instructions while taking Metformin + Saxagliptin?
  8. Follow the dietary instructions if recommended by the doctor while taking Metformin + Saxagliptin combination.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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