INTRODUCTION

KEZOP SOAP contains Ketoconazole which belongs to the group of medicines called Antifungals. It is used to treat various fungal infections of the skin such as ringworm, athlete’s foot and dermatitis associated with such infections.

KEZOP SOAP can also be used to treat other fungal infections like candida paronychia (fungal infection around nails), cutaneous candidiasis (fungal infection of the skin), and pityriasis versicolor (characterized by the development of hyper-pigmented patches on the trunk that may/may not spread to arms and shoulders).

Before using KEZOP SOAP, inform your doctor if you have any allergies or pre-existing conditions, or if you are taking any other medicines. KEZOP SOAP should be used cautiously in pregnant and breastfeeding women. The safety and effectiveness of KEZOP SOAP in children (less than 12 years of age) have not been established so, consult your child’s doctor for advice.

The most common side effects associated with KEZOP SOAP are skin dryness, itching, redness or burning sensation. It is recommended to consult the doctor if any of the symptoms worsen.

USES OF KEZOP SOAP

Treats various fungal infections of the skin such as:

• ringworm, athlete’s foot and dermatitis associated with such infections
• candida paronychia
• cutaneous candidiasis
• pityriasis versicolor

HOW KEZOP SOAP WORKS

KEZOP SOAP clears the infection by causing holes in the fungal cell membranes, thus killing the fungi.

DIRECTIONS FOR USE

Always apply KEZOP SOAP as directed by your physician. It is for external use only. Apply KEZOP SOAP on the affected area. It can be applied on the body and scalp. Wash and rinse thoroughly with water after applying KEZOP SOAP. Avoid contact of KEZOP SOAP with the nose, mouth or eyes.

If KEZOP SOAP accidentally gets in your eye, gently rinse your eyes with cold water. Your doctor will decide the right dose and duration of therapy for you according to your age, body weight and disease condition.

SIDE EFFECTS OF KEZOP SOAP

HOW TO MANAGE SIDE EFFECTS

Itching, dryness and burning sensation of skin:

Try to avoid the urge to scratch as it may lead to further damage. Keep your nails trimmed and clean. Use a gentle cleanser to wash the skin to avoid dirt and bacterial build-up. Do not rub the area roughly with a harsh cloth as it may cause more itching. Instead, let the area air-dry. Cover with a generous layer of moisturizer and stay hydrated. Applying ice packs may provide relief to the burning sensation of the skin. Consult your doctor if any of the symptoms remain or worsen.

WARNING & PRECAUTIONS

PREGNANCY

KEZOP SOAP should be used with caution in pregnant women as it is not known if this medicine will harm your unborn baby. Consult your doctor before using it.

BREASTFEEDING

KEZOP SOAP should be used with caution in breastfeeding women as it is not known if this medicine passes into your breast milk. Consult your doctor before using it.

ALLERGY

Do not use KEZOP SOAP if you are allergic to Ketoconazole or any of the other ingredients of this medicine.

INTERACTIONS

A. Drug-Drug Interactions

Before using KEZOP SOAP, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription or herbal medicine.

Overdosage:

If you or anyone else accidentally use too much of KEZOP SOAP, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep KEZOP SOAP out of reach of children
• Do not store above 25°C

FAQs ABOUT KEZOP SOAP

Can KEZOP SOAP be used on infants?

The safety and effectiveness of KEZOP SOAP in children (less than 12 years of age) have not been established. Consult your child’s doctor for advice. The doctor will determine an appropriate dose or select a suitable alternative treatment for your child.

What if KEZOP SOAP accidentally gets into my eyes, mouth or nose?

Avoid getting KEZOP SOAP into your eyes, mouth, or nose. In case it comes in contact with these areas accidentally, wash it with water thoroughly. Call your doctor if any discomfort occurs.

Can KEZOP SOAP be used by elderly people?

KEZOP SOAP is not recommended to be used by elders above the age of 65, due to lack of safety data. For patients below that age, it is recommended to be used only after consultation by a doctor.

Can KEZOP SOAP be used by pregnant women?

KEZOP SOAP should be used with caution in pregnant women as it is unknown if this medicine will harm your unborn baby. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before taking it.

Can I take other medicines with KEZOP SOAP?

Before using KEZOP SOAP, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, over the counter or any herbal medicine, as these might lead to serious side effects by interacting with each other.

REFERENCES

1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 791, 792.Raviteja Innamuri, Sudhir Nayak UK, Shrutakirthi D Shenoi. Open comparative study of efficacy and safety of ketoconazole soap and oral ketoconazole in tinea versicolor. Journal of Pakistan Association of Dermatologists. 2014. [Accessed on 11th October 2022] https://applications.emro.who.int/imemrf/J_Pak_Assoc_Dermatol/J_Pak_Assoc_Dermatol_2014_24_1_63_67.pdf

2. C.A. Green, P. M. Farr. S. Shuster. Treatment of seborrhoeic dermatitis with ketoconazole: II. Response of seborrhoeic dermatitis of the face, scalp and trunk to topical ketoconazole. BJD. British Journal of Dermatology. February 1987. [Accessed on 11th October 2022] https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2133.1987.tb05815.x

3. Padagis Israel Pharmaceuticals Ltd. Ketoconazole- ketoconazole aerosol, foam. [Revised in September 2022] [Accessed on 11th October 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=9b65f632-a98d-400e-9ec3-84dea581d6a3&type=display   

4. VKAN Healthcare. Vabderm-K (Ketoconazole 1% soap). [Accessed on 14th October 2022] http://www.vkanhealthcare.com/ketoconazole-soap-4779042.html

5. Integrated Labortaries. Inte- Ket Soap (Ketoconazole 2%). [Accessed on 11th October 2022] https://integratedlaboratories.in/ketoconazole-2-inte-ket-soap/

AUTHOR DETAILS

Written By Dr. Jeenal Rajani, Pharm.D.
Last updated on 27 Oct 2022 | 03:52 PM(IST)