INTRODUCTION

KETONOL SHAMPOO contains Ketoconazole which belongs to the group of medicines called Antifungals. It is used to treat fungal infections on scalp and body such as dandruff, seborrheic dermatitis (a dry or oily scaling of the scalp and other parts of the body) and tinea versicolor.

These conditions can by itchy, caused by a fungus called ‘Malassezia’. Tinea versicolor is characterized by white to brown patches on the body that sometimes appear after exposure to the sun.

Before using KETONOL SHAMPOO, inform your doctor if you have any liver problems or if you are using any steroids. KETONOL SHAMPOO can be usually used by pregnant and breastfeeding women but consult your doctor for advice. KETONOL SHAMPOO is not recommended for use in infants and children.

The most common side effects of using KETONOL SHAMPOO are itching, stinging and dryness on the site of application. Call your doctor if any of the symptoms get worse.

USES OF KETONOL SHAMPOO

Treats fungal infections like:

• dandruff
• seborrheic dermatitis
• tinea versicolor

HOW KETONOL SHAMPOO WORKS

KETONOL SHAMPOO works by arresting growth in fungal cells thus, preventing growth and spread of the fungus throughout your body.

DIRECTIONS FOR USE

Use KETONOL SHAMPOO as advised by your physician. It is for use on hair and skin only. Wet your hair and scalp thoroughly with water and apply sufficient amount of KETONOL SHAMPOO to produce enough lather. Smoothly massage the lather over the entire scalp. Leave for 3-5 minutes, before washing off thoroughly.

If KETONOL SHAMPOO accidentally gets in your eye, gently rinse your eyes with cold water. Do not swallow it. Your doctor will decide the right dose and duration of therapy for you according to your age, body weight and disease condition.

SIDE EFFECTS OF KETONOL SHAMPOO

HOW TO MANAGE SIDE EFFECTS

Skin irritation or burning:

Do not share vessels, personal items or cosmetics with others. Use disinfectants on objects you use in public spaces, such as gym equipment. Drink sufficient water and have a nutritious diet. Do not use irritants or harsh chemicals. Sleep seven to eight hours every night. Use sunscreens to prevent sunburn and other sun damage. Wash hands regularly with soap and water.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before using KETONOL SHAMPOO, inform your doctor if you are using the following medicine:

• medicines used in inflammatory conditions (Ex. betamethasone, hydrocortisone)

Overdosage:

If you or anyone else accidentally use too much of KETONOL SHAMPOO, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep KETONOL SHAMPOO out of reach of children
• Do not store above 25°C

FAQs ABOUT KETONOL SHAMPOO

Can KETONOL SHAMPOO interact with other medicines?

Before using KETONOL SHAMPOO, inform your doctor if you have been using steroid medicines such as betamethasone or hydrocortisone for a long period of time as these might interact with each other. You must gradually reduce their use over 2 to 3 weeks as you start to use KETONOL SHAMPOO. Also inform your doctor if you are taking, have taken or might take any other medicine, including prescription, over the counter or any herbal medicine.

How often should I use KETONOL SHAMPOO?

For dermatitis and dandruff, use KETONOL SHAMPOO twice weekly for 2–4 weeks. For tinea, use once daily for maximum 5 days. However, the dose and duration might differ for each patient so, consult your doctor before using it. Your doctor will decide the right dose and duration of therapy for you according to your age, body weight and disease condition.

What if KETONOL SHAMPOO gets in my eye?

Use KETONOL SHAMPOO with care and avoid getting it in your eyes or mouth. If it gets in your eye, gently rinse your eyes with cold water. If any discomfort persists, consult your doctor.

What if I swallow KETONOL SHAMPOO?

Accidental swallowing of small quantities of KETONOL SHAMPOO is usually harmless but, consult your doctor or go to the nearest hospital immediately in case you swallow it.

What if I forget to use KETONOL SHAMPOO?

If you forget to use KETONOL SHAMPOO, use it as soon as you remember and then continue your treatment as usual. Do not use the medicine twice to make up for the missed treatment.

REFERENCES

1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 791, 792

2. Choi FD, Juhasz MLW, Atanaskova Mesinkovska N. Topical ketoconazole: a systematic review of current dermatological applications and future developments. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed.gov. December 2019. [Accessed on 13th October 2022] https://pubmed.ncbi.nlm.nih.gov/30668185/

3. Hadeer Sinawe, Damian Casadesus. Ketoconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed on 13th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK559221/

4. Janssen Pharmaceutica NV. Electronic Medicines Compendium (EMC). [Revised in July 2020] [Accessed on 13th October 2022] https://www.medicines.org.uk/emc/files/pil.1510.pdf

5. Pinewood Laboratories Ltd. Health Products Regulatory Authority (HPRA). [Revised in May 2020] [Accessed on 13th October 2022] http://www.hpra.ie/img/uploaded/swedocuments/83695f95-ccd3-4e5e-91fe-11fd592f9721.pdf

6. Nanz MedScience Pharma (P) Ltd. Ketonol (Anti-dandruff Scalp Solution). [Accessed on 13th October 2022] https://nanzpharma.com/hospiaid/

7. Alniche Life Sciences Pvt. Ltd. Nizral 2%. [Accessed on 13th October 2022] https://www.alniche.com/product/nizral-2/

8. Ketoconazole. Drugbank. [Accessed on 13th October 2022] https://go.drugbank.com/drugs/DB01026