INTRODUCTION

KAPSPAS TABLET is a combination of Dicyclomine and Paracetamol which belongs to the group of medicines called Antispasmodics and Analgesics, respectively. KAPSPAS TABLET is used to provide relief from spasmodic pain and discomfort due to biliary colic (abdominal pain), intestinal colic (intestinal pain), renal colic (sharp pain due to kidney dysfunction), and spasmodic dysmenorrhea (sharp pelvic pain at the start of menstrual flow) in affected individuals.

KAPSPAS TABLET is also used to provide relief from the symptoms of irritable bowel syndrome (IBS) and functional bowel disease.

KAPSPAS TABLET is not recommended for use in patients allergic to dicyclomine, and paracetamol. It is also not recommended for use in patients with liver problems such as severe hepatic insufficiency and in patients with a history of known idiosyncrasy (adverse effect) to dicyclomine.

Before taking KAPSPAS TABLET, inform your doctor if you have/ suspected of having glaucoma (increased eye pressure), prostatic hypertrophy (prostate gland enlargement), Gilbert’s syndrome (inherited liver disorder), liver problems (such as mild to moderate hepatic insufficiency), and/or kidney problems (such as severe renal insufficiency).

KAPSPAS TABLET should be used with caution in pregnant and breastfeeding women only if it is clearly necessary. KAPSPAS TABLET is not recommended for use in children & adolescents (aged below 12 years) and in elderly patients. Consult your doctor before taking KAPSPAS TABLET.

The most common side effects of taking KAPSPAS TABLET are hypersensitivity reaction (immune mediated reaction), dry mouth, stomach upset, bloating, flatulence, vomiting, and/or constipation. Consult your doctor if any of these symptoms worsens.

USES OF KAPSPAS TABLET

• Provides relief from spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic and spasmodic dysmenorrhea
• Provides relief from the symptoms of irritable bowel syndrome (IBS) and functional bowel disease

HOW KAPSPAS TABLET WORKS

KAPSPAS TABLET provides relief from spasmodic pain and discomfort, where Dicyclomine relieves abdominal cramps, pain, bloating and discomfort by relaxing the muscles in the stomach & gut and preventing the occurrence of sudden muscle contractions and Paracetamol provides relief from pain by blocking the action of prostaglandin (chemical messengers responsible for pain) thus providing reducing spasmodic pain and discomfort in affected individuals.

DIRECTIONS FOR USE

Take KAPSPAS TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF KAPSPAS TABLET

HOW TO MANAGE SIDE EFFECTS

Dry mouth:

Try to drink plenty of cold water and sip on cold unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.

Vomiting:

Take KAPSPAS TABLET with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.

Constipation:

Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.

WARNING & PRECAUTIONS

PREGNANCY

KAPSPAS TABLET should be used with caution during pregnancy only if it is clearly necessary. Consult your doctor before taking KAPSPAS TABLET.

BREASTFEEDING

KAPSPAS TABLET should be used with caution in breastfeeding women only if it is clearly necessary since the medicine may get excreted in breast milk. Consult your doctor before taking the medicine.

DRIVING AND USING MACHINES

KAPSPAS TABLET is unlikely to affect your ability to drive and/or operate machines. Consult your doctor before taking the medicine.

ALCOHOL

Avoid consumption of alcohol while taking KAPSPAS TABLET as it may increase the risk of intoxication.

KIDNEY

KAPSPAS TABLET should be used with caution in patients with kidney problems such as severe renal insufficiency. Contact your doctor before taking KAPSPAS TABLET.

LIVER

KAPSPAS TABLET is not recommended for use in patients with liver problems such as severe hepatic insufficiency. It should be used with caution in patients with mild to moderate hepatic insufficiency and other liver disorders. Consult your doctor before taking the medicine.

ALLERGY

Do not take KAPSPAS TABLET if you are allergic to dicyclomine, paracetamol, and/or any other ingredients of this medicine.

INTERACTIONS

A. Drug-Drug interactions:

Before taking KAPSPAS TABLET, inform your doctor if you are taking any of the following medicine:

• antiepileptics (use to treat epilepsy) Ex. phenobarbital, phenytoin, carbamazepine, topiramate
• rifampicin (used to treat tuberculosis)
• medicines used to prevent blood clots such antivitamin K (Ex. warfarin)
• flucloxacillin (used to treat skin, wound, bone infections)
• chelating resin (medicine used to treat mercury & lead toxicity, and blood transfusion dependent anaemias)
• metoclopramide, domperidone (used to stop nausea and vomiting)

Overdosage:

If you or anyone else accidentally take too much of KAPSPAS TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are abdominal pain, pallor, headache, dizziness, nausea, dry mouth, difficulty in swallowing, anorexia, dilated pupils, dry skin, hepatic cytolysis (harmful immunoallergic reaction which leads to liver failure), gastrointestinal bleeding, metabolic acidosis (excess acid production in the body), encephalopathy (brain disease that alters brain function), disseminated intravascular coagulation (serious blood disorder that affects bleeding), pancreatitis (inflammation of pancreas), pancytopenia (deficiency of red blood/white blood/platelets), acute renal failure, and coma.

SYNOPSIS

MORE INFORMATION

• Keep KAPSPAS TABLET out of reach of children
• Do not store KAPSPAS TABLET above 30°C

FAQs ABOUT KAPSPAS TABLET

What is KAPSPAS TABLET used for?

KAPSPAS TABLET is used to provide relief from spasmodic pain and discomfort due to biliary colic (abdominal pain), intestinal colic (intestinal pain), renal colic (sharp pain due to kidney dysfunction), and spasmodic dysmenorrhea (sharp pelvic pain at the start of menstrual flow) in affected individuals. It is also used to provide relief from the symptoms of irritable bowel syndrome (IBS) and functional bowel disease in affected individuals.

How to take KAPSPAS TABLET?

Take KAPSPAS TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

What are the side effects of KAPSPAS TABLET?

The most common side effects of taking KAPSPAS TABLET are hypersensitivity reaction (immune mediated reaction), dry mouth, stomach upset, bloating, flatulence, vomiting, and/or constipation. Consult your doctor if any of these symptoms worsens.

How KAPSPAS TABLET works?

KAPSPAS TABLET provides relief from spasmodic pain and discomfort, where Dicyclomine relieves abdominal cramps, pain, bloating and discomfort by relaxing the muscles in the stomach & gut and preventing the occurrence of sudden muscle contractions and Paracetamol provides relief from pain by blocking the action of prostaglandin (chemical messengers responsible for pain) thus providing reducing spasmodic pain and discomfort in affected individuals.

Can KAPSPAS TABLET be used in pregnant and breastfeeding women?

Yes, KAPSPAS TABLET can be used but with caution in pregnant and breastfeeding women only if it is clearly necessary. Consult your doctor before taking the medicine.

REFERENCES

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2. KD. Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 206.

3. Dicyclomine. NIH National Library of Medicine. National center for biotechnology information. PubChem. October 2022. [Accessed on 12th September 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Dicyclomine#section=Metabolism-Metabolites

4. Marta Józwiak-Bebenista, Jerzy Z Nowak. Paracetamol: mechanism of action, applications and safety concern.  NIH National Library of Medicine. National center for biotechnology information. PubMed.gov. 2014. [Accessed on 12th September 2022] https://pubmed.ncbi.nlm.nih.gov/24779190/

5. Audrey Rankin, Cathal A Cadogan, Susan M Patterson, Ngaire Kerse, Chris R Cardwell, Marie C Bradley, Cristin Ryan, Carmel Hughes, Cochrane Effective Practice and Organisation of Care Group.  Interventions to improve the appropriate use of polypharmacy for older people. NIH National Library of Medicine. National center for biotechnology information. PMC PubMed Central. 2018. [Accessed on 12th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513645

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8. Mapro Lifescience. Cyclopex. [Accessed on 12th September 2022] https://maprolifescience.com/product/cyclopex/

9. SunLife Sciences Pvt Ltd. Cyclosun. [Accessed on 12th September 2022] https://www.sunlifesciences.in/product/cyclosun/

10. Sanofi S.A. Baralgan NU. [Revised in August 2021] [Accessed on 12th September 2022] https://www.sanofi.in/dam/jcr:79ac7a65-edc5-434b-84d2-bb22fa2d25fa/Baralgan%20NU%20PI%20_Aug%202021.pdf

AUTHOR DETAILS

Written By Dr. K .AZEEM HUSSAIN, B.D.S
Last updated on 22 Nov 2022 | 01:26 PM(IST)