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ITRATUF 100mg Capsule 15's
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INTRODUCTION
ITRATUF 100MG CAPSULE contains Itraconazole which belongs to the group of medicines called Anti-fungals. It is used to treat infections of the mouth or vagina (causing thrush), skin infections and infections affecting other parts of the body.
Fungal infections also known as mycosis is a disease caused by fungus, which can affect people of all age groups. People with injuries and suppressed immune system are more susceptible to fungal infections.
ITRATUF 100MG CAPSULE should be used with caution in patients with kidney or liver problems and heart problems such as heart failure. ITRATUF 100MG CAPSULE is not recommended for use in patients when the immune system is not functioning well or have acquired immunodeficiency syndrome (AIDS).
Do not take any medicine without consulting your doctor while on treatment with ITRATUF 100MG CAPSULE especially medicines given to treat indigestion or stomach ulcers. If the duration of the treatment with ITRATUF 100MG CAPSULE is more than a month your doctor will advise you to take some blood tests to monitor your liver function.
ITRATUF 100MG CAPSULE is not recommended for use in pregnant women unless advised by the doctor and it is not recommended for use in breast-feeding women. ITRATUF 100MG CAPSULE is not recommended for use in children less than 12 years of age, however your child’s doctor may advise them in special cases.
ITRATUF 100MG CAPSULE is normally not recommended for use in elderly patients, however, your doctor may prescribe them in special cases. The common side effects of taking ITRATUF 100MG CAPSULE are stomach pain, nausea and headache. Consult your doctor if any of the side effects worsen.
USES OF ITRATUF 100MG CAPSULE
- infections of the mouth or vagina (causing thrush)
- skin infections and infections affecting other parts of the body
HOW ITRATUF 100MG CAPSULE WORKS
ITRATUF 100MG CAPSULE works by preventing the fungal growth by blocking the production of enzymes responsible for the growth of fungal cell. This inhibition results in breakage of cell membranes and fungal cell abnormalities, finally leading to alterations in membrane-based activity of fungus. These leads to fungal cell death and prevention of further fungal growth.
DIRECTIONS FOR USE
Take ITRATUF 100MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of ITRATUF 100MG CAPSULE for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF ITRATUF 100MG CAPSULE
COMMON
- stomach pain, nausea
- headache
UNCOMMON
- irregular menstrual cycle
- sinusitis, runny nose, coughs, sneezing
- constipation, diarrhoea, flatulence
- vomiting, indigestion
RARE
- increased frequency of urine
- blurred or double vision
- taste changes
- blood disorders increase the risk of infections
- ringing in ears
- hearing loss (may be permanent)
- swelling due to fluid under the skin, hair loss
- redness, itching, flaking or peeling skin
- sensitivity of the skin to light
- erection problems
Stop taking ITRATUF 100MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reaction (signs include swelling of the lips, face, throat, tongue or other parts of the body, rash, hives and severe irritation of the skin)
- tingling, numbness and weakness in the limbs
- severe skin disorders with peeling or rashes with small pustules (with a fever) or blistering of the skin, mouth, eyes and genitals with fever, chills, aching muscles and generally feeling unwell
- liver problems (sings include severe lack of appetite, nausea, vomiting, tiredness, stomach pain, muscle weakness, yellowing of skin and eyes (jaundice), dark urine, pale stools, hair loss)
- heart failure (sings include shortness of breath, weight gain, swelling of legs and abdomen, tiredness, breathing difficulties at night)
HOW TO MANAGE SIDE EFFECTS
Headache:
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Nausea or vomiting:
Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Diarrhoea:
Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.
Stomach pain:
Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.
WARNING & PRECAUTIONS
PREGNANCY
ITRATUF 100MG CAPSULE is not recommended for use in pregnant women unless advised by the doctor. You should use contraception to make sure that you do not become pregnant during treatment with this medicine. Consult your doctor before taking ITRATUF 100MG CAPSULE.
BREASTFEEDING
ITRATUF 100MG CAPSULE is not recommended for use in breast-feeding women as small amount of this medicine passes into breast milk. Consult your doctor before taking ITRATUF 100MG CAPSULE.
DRIVING AND USING MACHINES
Do not drive or handle heavy machines if you experience dizziness, blurred/double vision or hearing loss while taking ITRATUF 100MG CAPSULE.
ALCOHOL
Consumption of alcohol is not recommended during treatment with ITRATUF 100MG CAPSULE.
KIDNEY
ITRATUF 100MG CAPSULE should be used with caution in patients with kidney problems. Consult your doctor before taking ITRATUF 100MG CAPSULE.
LIVER
ITRATUF 100MG CAPSULE should be used with caution in patients with liver problems such as jaundice. Consult your doctor before taking ITRATUF 100MG CAPSULE.
ALLERGY
Do not take ITRATUF 100MG CAPSULE if you are allergic to itraconazole or any other ingredients of this medicine.
HEART DISEASE
ITRATUF 100MG CAPSULE should be used with caution in patients with heart problem such as heart failure. Consult your doctor before taking ITRATUF 100MG CAPSULE.
OTHERS
ITRATUF 100MG CAPSULE is not recommended for use if you:
- have acquired immunodeficiency syndrome (AIDS) or your immune system is not functioning well
Use in paediatrics:
ITRATUF 100MG CAPSULE is not recommended for use in children less than 12 years of age. However, your child’s doctor may advise them in special cases. Consult your child’s doctor for advice before giving ITRATUF 100MG CAPSULE to your child.
Use in geriatrics:
ITRATUF 100MG CAPSULE is not recommended for use in elderly patients. However, your doctor may prescribe them in special cases. Consult your doctor before taking ITRATUF 100MG CAPSULE.
INTERACTIONS
A. Drug-Drug interactions:
Before taking ITRATUF 100MG CAPSULE, inform your doctor if you are taking any of the following medicines:
- medicines used to treat allergies or hay fever Ex. terfenadine, astemizole, ebastine, mizolastine
- medicines used to lower blood cholesterol levels Ex. atorvastatin, lovastatin, simvastatin
- medicines used to treat irregular heartbeat Ex. quinidine, disopyramide, dronedarone or dofetilide
- medicines used to treat chest pain and high blood pressure Ex. bepridil, , lercanidipine, ivabradine, ranolazine, nisoldipine, aliskiren, nadolol, digoxin, cilostazol dihydropyridines such as amlodipine, felodipine, verapamil
- medicines used to treat migraine headaches Ex. dihydroergotamine, eletriptan, ergotamine
- medicines used to treat drug abuse Ex. levacetylmethadol and methadone
- medicines used to treat digestive problems Ex. cisapride
- colchicine (used to treat gout)
- medicines used to treat fluid accumulation Ex. Eplerenone
- medicines used after labour Ex. ergometrine, methylergometrine
- medicine used to treat malaria Ex. halofantrine
- medicines used to treat cancer Ex. irinotecan, bortezomib, busulphan, docetaxel, erlotinib, ixabepilone, trimetrexate, axitinib, dabrafenib, dasatinib, ibrutinib, lapatinib, nilotinib, sunitinib and trabectedin
- medicines used as blood thinners Ex. dabigatran, ticagrelor, rivaroxaban, warfarin
- medicines used to treat mental illness Ex. quetiapine, pimozide, lurasidone, aripiprazole, haloperidol, perospirone, ramelteon, risperidone, reboxetine, and sertindole
- medicines used to treat urinary bladder disorders Ex. darifenacin, tamsulosin, fesoterodine, imidafenacin, solifenacin, tolterodine
- medicines used to treat anxiety Ex. midazolam, triazolam, buspirone, alprazolam, brotizolam
- medicines used after an organ transplant Ex. everolimus, ciclesonide, temsirolimus, ciclosporin, tacrolimus, sirolimus
- medicines used to relive pain Ex. fentanyl, alfentanil, buprenorphine, oxycodone
- medicines used to treat inflammation or asthma Ex. salmeterol, methylprednisolone, fluticasone, budesonide, dexamethasone
- medicines used to treat erection problems Ex. vardenafil, sildenafil and tadalafil
- medicines used to treat indigestion, stomach ulcers or heartburn Ex. Pantoprazole, omeprazole
- medicines used to treat HIV infection Ex. ritonavir, darunavir, indinavir, fosamprenavir, saquinivir
- medicines used to treat bacterial infections Ex. ciprofloxacin, clarithromycin, erythromycin
- medicines used to treat tuberculosis Ex. rifampicin, rifabutin or isoniazid
- medicines used to treat epilepsy Ex. phenytoin, carbamazepine or phenobarbital
- st. john’s wort (used to treat depression)
- medicines used to treat eczema Ex. alitretioin
- medicines used to treat vomiting Ex. aprepitant, domperidone
- medicines used to treat excess thyroid hormone secretion Ex. cinacalcet
- medicines used to treat low sodium blood levels Ex. mozavaptan or tolvaptan
- medicines used to treat worms Ex. praziquantel
- medicines used to treat high blood sugar Ex. Repaglinide, saxagliptin
- medicines used to relive inflammation and pain Ex. meloxicam
Overdosage:
If you or anyone else accidentally takes too much of ITRATUF 100MG CAPSULE, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Itraconazole |
| Pharmacological Category | : | Anti-fungals |
| Therapeutic Indication | : | Fungal infections of the mouth, vagina, skin and other body parts |
| Dosage Forms | : | Oral Solution, Suspension, Capsule, Tablet, Cream, Dusting Powder, Eye Drops, Eye Ointment, Gel, Ointment, Powder, Soap |
MORE INFORMATION
- Keep ITRATUF 100MG CAPSULE out of reach of children
- Store ITRATUF 100MG CAPSULE at room temperature
FAQs ABOUT ITRATUF 100MG CAPSULE
What is ITRATUF 100MG CAPSULE used for?
ITRATUF 100MG CAPSULE contains itraconazole which belongs to the group of medicines called anti-fungals. It is used to treat infections of the mouth or vagina (causing thrush), skin infections and infections affecting other parts of the body.
How does ITRATUF 100MG CAPSULE work?
ITRATUF 100MG CAPSULE works by preventing the fungal growth by blocking the production of enzymes responsible for the growth of fungal cell. This inhibition results in breakage of cell membranes and fungal cell abnormalities, finally leading to alterations in membrane-based activity of fungus. These leads to fungal cell death and prevention of further fungal growth.
Does ITRATUF 100MG CAPSULE cause stomach pain?
The most common side effect of ITRATUF 100MG CAPSULE is stomach pain. To manage this effect, try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.
Is ITRATUF 100MG CAPSULE safe to use in pregnant women?
ITRATUF 100MG CAPSULE is not recommended for use in pregnant women unless advised by the doctor. You should use contraception to make sure that you do not become pregnant during treatment with this medicine. Consult your doctor before taking ITRATUF 100MG CAPSULE.
Can ITRATUF 100MG CAPSULE be used in children?
ITRATUF 100MG CAPSULE is not recommended for use in children less than 12 years of age. However, your child’s doctor may advise them in special cases. Consult your child’s doctor for advice.
REFERENCES
1. K.D. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page 794.
2. Heidi Kurn; Roopma Wadhwa. Itraconazole. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. April 2022. [Accessed on 7th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK557874/
3. Stiefel, a GSK Company. Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail. NIH. National Library of medicine. Clinical trials.gov. [Revised in February 2017] [Accessed on 7th July 2022] https://clinicaltrials.gov/ct2/show/NCT00356915
4. Laboratorios Liconsa, S.A. Electronic Medicines Compendium (EMC) [Revised in January 2021] [Accessed on 7th July 2022] https://www.medicines.org.uk/emc/files/pil.5914.pdf
5. Janssen Pharmaceutical Companies [Revised in May 2018] [Accessed on 7th July 2022] https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/SPORANOX-Capsules-pi.pdf
6. Mint Pharmaceuticals Inc Health Canada [Revised in March 2018] [Accessed on 7th July 2022] https://pdf.hres.ca/dpd_pm/00044442.PDF
7. Mayne Pharma International Pty Ltd [Revised in April 2020] [Accessed on 7th July 2022] https://www.nps.org.au/medicine-finder/lozanoc-capsules#product-description
USEFUL DIAGNOSTIC TESTS
- Complete blood count
- Fungal culture test
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 05 Oct 2022 | 05:03 PM(IST)
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