HALOTOP F Cream 15gm

INTRODUCTION

HALOTOP F CREAM is a combination of Fusidic acid and Halobetasol which belongs to the group of medicines called Antibiotics and Topical Corticosteroids respectively. It is used to treat bacterial skin infections, eczema, seborrhoeic & contact dermatitis, psoriasis and infected dermatoses.

Atopic dermatitis (eczema) is a condition that causes dry, itchy and inflamed skin. Psoriasis is a skin disease that causes a rash with itchy, scaly patches, most commonly on the knees, elbows, trunk and scalp. Infectious dermatoses that can manifest as vesicles include bacteria, viruses, fungi, syphilis and other infections.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, consult your doctor before using this medicine. The most common side effect of this medicine is application site reactions (burning, irritation, itching, and redness). Consult your doctor if the above side effects worsen or persists for a longer duration.

USES OF HALOTOP F CREAM

It is used to treat:

• bacterial skin infections
• eczema
• seborrhoeic & contact dermatitis
• psoriasis
• infected dermatoses

HOW HALOTOP F CREAM WORKS

HALOTOP F CREAM is a combination of Halobetasol and Fusidic acid. Halobetasol is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Fusidic Acid is an antibiotic that works against bacteria by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

DIRECTIONS FOR USE

Apply HALOTOP F CREAM as directed by your physician. It is for external use only. Apply a thin layer of this medicine on the affected area. Do not use this medicine on your face for more than 5 days. Avoid applying this medicine around your eyes, including eyelids.

SIDE EFFECTS OF HALOTOP F CREAM

WARNING & PRECAUTIONS

PREGNANCY

Consult your doctor

If you are pregnant or think you may be pregnant, consult your doctor before using this medicine.

BREASTFEEDING

Consult your doctor

If you are breast-feeding or planning to have a baby, consult your doctor before using this medicine.

ALLERGY

Contraindicated

Do not use if you are allergic to Fusidic acid and Halobetasol or any of the other ingredients of this medicine.

INTERACTIONS

A. Drug-Drug interactions:

Inform to your physician, if you are taking or using any prescription, non-prescription medicines and herbal supplements.

Overdosage:

If you or anyone else accidentally uses too much or a small quantity of HALOTOP F CREAM is accidentally swallowed, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store at a room temperature

FAQs ABOUT HALOTOP F CREAM

Q: Can I stop HALOTOP F CREAM when my symptoms are relieved?

A: Do not stop using HALOTOP F CREAM on your own even if the symptoms are relieved until the full course advised by the doctor is finished.

Q: What precaution is to be taken if more HALOTOP F CREAM is used?

A: If you or anyone else accidentally uses too much or a small quantity of HALOTOP F CREAM is accidentally swallowed, consult your doctor immediately or visit the nearby hospital.

Q: What happens if I forget to use HALOTOP F CREAM?

A: If you miss a dose of HALOTOP F CREAM, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Q: How does HALOTOP F CREAM work?

A: HALOTOP F CREAM is a combination of Halobetasol and Fusidic acid. Halobetasol is a steroid that blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Fusidic Acid is an antibiotic that works against bacteria by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

REFERENCES

1. C.M. Chakole, M.A. Shende, S.N. Khadatkar, Chandrashekhar Chakole. Formulation and evaluation of novel combined halobetasol propionate and fusidic acid ointment. International Journal of ChemTech Research. January 2009. [Accessed on 13th June 2022] https://www.researchgate.net/journal/International-Journal-of-ChemTech-Research-0974-4290

2. Rajesh Ankam, K. Mukkanti, S. Durgaprasad, P.V.L. Naidu. Simultaneous Determination of Halobetasol Propionate and Fusidic Acid Related Substances by Reversed Phase High Performance Liquid Chromatographic Method. Asian Journal of Chemistry. May 2010. [Accessed on 13th June 2022] 289360082_Simultaneous_Determination_of_Halobetasol_Propionate_and_Fusidic_Acid_Related_Substances_by_Reversed_Phase_High_Performance_Liquid_Chromatographic_Method

3. Prabhavathi Fernandes. Fusidic Acid: A Bacterial Elongation Factor Inhibitor for the Oral Treatment of Acute and Chronic Staphylococcal Infections. Cold Spring Harbor Perspectives in Medicine. January 2016. [Accessed on 13th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691801/

4. Paulina Carvajal-Vidal, ORCID, Mireia Mallandrich, María Luisa García and Ana Cristina. Effect of Different Skin Penetration Promoters in Halobetasol Propionate Permeation and Retention in Human Skin. International Journal of Molecular Sciences. November 2017. [Accessed on 13th June 2022] https://www.mdpi.com/1422-0067/18/11/2475/htm

5. LEO Laboratories Limited. Electronic Medicines Compendium (EMC). [Revised on November 2021] [Accessed on 8th June 2022] https://www.medicines.org.uk/emc/files/pil.5510.pdf

6. Reliable Laboratories. Electronic Medicines Compendium (EMC). [Revised in November 2019] [Accessed on 13th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25626b46-78f8-7226-e054-00144ff8d46c