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INTRODUCTION
FLUCOS 400MG contains Fluconazole belongs to a group of medicines called antifungals. It is used to treat the infections caused by fungi and soothes irritated skin and relieves the fungal itch. It works by stopping fungi and yeasts from producing a substance called ergosterol, which is an essential component of their cell membranes. This causes holes to appear in cell membranes, which allows essential constituents of the fungal or yeast cells to leak out.
Always take this medicine as directed by physician. Your doctor will decide the dose and duration of therapy depending upon your age, weight and condition. Swallow the medicine with a glass of water. It is recommended for the use in children and adolescents as advised by a doctor. Do not take FLUCOS 400MG if you have abnormal levels of potassium, calcium or magnesium in your blood. It should be used with caution in the pregnant or breastfeeding women. Consult your doctor before taking this medicine. Tell your doctor, if you are taking or taken or might take any other medicines. The most common side effects include headache, stomach discomfort, diarrhea, feeling sick, vomiting, increases in blood tests of liver function and rash.
USES OF FLUCOS 400MG
- Treat fungal infections
HOW FLUCOS 400MG WORKS
FLUCOS 400MG works by stopping fungi and yeasts from producing a substance called ergosterol, which is an essential component of their cell membranes. This causes holes to appear in cell membranes, which allows essential constituents of the fungal or yeast cells to leak out.
DIRECTIONS FOR USE
Always take FLUCOS 400MG exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. If you take more this medicine than you should, talk to your doctor. The signs of overdose can include hearing, seeing, feeling and thinking things that are not real (hallucination and paranoid behaviour).
SIDE EFFECTS OF FLUCOS 400MG
SERIOUS
- sudden wheezing
- difficulty in breathing or tightness in chest
- swelling of eyelids, face or lips
- itching, reddening of the skin or itchy red spots
- skin reactions such as rash that causes the blistering
COMMON
- headache
- stomach discomfort, diarrhea
- feeling sick, vomiting
- increases in blood tests of liver function
- rash
RARE
- hair loss
- red or purple discoloration of the skin
- high blood levels of cholesterol, fats
- low blood potassium
- shaking
- change in heart rate or rhythm
- liver failure
HOW TO MANAGE SIDE EFFECTS
Skin itching:
Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.
Nausea and vomiting:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Diarrhea:
Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.
WARNING & PRECAUTIONS
PREGNANCY
FLUCOS 400MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
FLUCOS 400MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machinery while taking this medicine, it may make you feel dizziness.
ALCOHOL
Consumption of alcohol is not recommended during treatment with FLUCOS 400MG.
KIDNEY
FLUCOS 400MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
FLUCOS 400MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take if you are allergic to this medicine.
HEART DISEASE
FLUCOS 400MG should be taken with caution in patients with severe heart disease. Consult your doctor for advice.
OTHERS
Do not take FLUCOS 400MG if you:
- have abnormal levels of potassium, calcium or magnesium in your blood
INTERACTIONS
Talk to your doctor if you are taking:
- terfenadine or astemizole (an antihistamine for allergies)
- cisapride (used for stomach upsets)
- quinidine (used for treating heart arrhythmia)
- pimozide (for treating a mental disorder (Schizophrenia)
- erythromycin (an antibiotic for treating infections)
SYNOPSIS
| Drug | : | Fluconazole |
| Pharmacological Category | : | Antifungal |
| Therapeutic Indication | : | Fungal infections |
| Dosage Forms | : | Tablet, Capsule, Dusting powder, Ear drops, Eye drops, Injection |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT FLUCOS 400MG
Can FLUCOS 400MG be used in pregnant women?
No. It is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
Will FLUCOS 400MG treat UTI?
It is approved for used in the treatment of candidal UTIs, but dosage recommendations are not consistent.
What infections does FLUCOS 400MG treat?
It is used to treat the fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections).
REFERENCES
1. Carla Garcia-Cuesta, Maria-Gracia Sarrion-Pérez and Jose V. Bagán; Current treatment of oral candidiasis: A literature review; [Revised on Dec 2014] [Accessed 02 Jan 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312689/
2. Ameish Govindarajan; Karlyle G. Bistas; Ayham Aboeed, Fluconazole, [Revised on Apr 2020] [Accessed 02 Jan 2021] https://www.ncbi.nlm.nih.gov/books/NBK537158/
3. K.D.Tripathi, Essentials of medical pharmacology, ANTIMICROBIAL DRUGS, Chapter 57 – Antifungal Drugs, 7th edition 2013, Page – 793.
4. Accord Healthcare Limited, Electronic Medicines Compendium (EMC); [Revised on Oct 2020] [Accessed 02 Jan 2021] https://www.medicines.org.uk/emc/files/pil.6086.pdf
5. Sun Pharmaceutical Industries Europe B.V.; Electronic Medicines Compendium (EMC); [Revised on Dec 2018] [Accessed 02 Jan 2021] https://www.medicines.org.uk/emc/files/pil.4438.pdf
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