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INTRODUCTION
ENTALIV 0.5MG contains Entecavir which belong to anti-viral medicines. It is used to treat chronic hepatitis B virus infection in adults whose has compensated liver disease in which liver is damaged but still functions properly and in people having decompensated liver disease where the liver is damaged and does not function properly. It reduces the amount of Hepatitis B virus in your body and helps in preventing liver damage. It should not be used for children below 2 years of age or weighing less than 10 kg.
Always take ENTALIV 0.5MG as directed by your physician. Your doctor will decide the dose and duration of the therapy depending upon your age, weight and condition. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Do not stop taking this medicine unless told by your doctor, since it may worsen the hepatitis infection. Your doctor will continue to monitor you and take blood tests for several months after stopping the treatment. You may experience dizziness, tiredness and sleepiness which may impair your ability to drive and use machines while taking this medicine. Consult your doctor for advice. The most common side effects are headache, tiredness, dizziness, nausea, diarrhea, indigestion, vomiting, sleepiness, trouble sleeping.
USES OF ENTALIV 0.5MG
- Treat chronic infection with hepatitis B virus (HBV)
HOW ENTALIV 0.5MG WORKS
ENTALIV 0.5MG inhibits reverse transcription, DNA replication and transcription in the viral replication process. It reduces the amount of HBV in blood by reducing the ability to multiply and infect new cells.
DIRECTIONS FOR USE
Always take ENTALIV 0.5MG as directed by your physician. Your doctor will decide the dose and duration of the therapy depending upon your age, weight and condition. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
SIDE EFFECTS OF ENTALIV 0.5MG
SERIOUS
- lactic acidosis and liver problems
COMMON
- headache, tiredness
- dizziness, nausea
- diarrhea, indigestion, vomiting
- sleepiness, trouble sleeping
RARE
- allergic reaction
HOW TO MANAGE SIDE EFFECTS
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Nausea or vomiting:
Try taking this medicine with, or just after, a meal and stick to simple meals.
Diarrhea:
Drink lot of fluid to avoid dehydration. Avoid taking any other medicines without speaking to a doctor.
Skin redness:
Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.
WARNING & PRECAUTIONS
PREGNANCY
ENTALIV 0.5MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.
BREASTFEEDING
ENTALIV 0.5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
You may experience dizziness, tiredness and sleepiness which may affect your ability to drive and use machines while taking this medicine. Consult your doctor for advice.
ALCOHOL
Avoid consumption of alcohol while taking this medicine.
KIDNEY
ENTALIV 0.5MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
ENTALIV 0.5MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take if you are allergic to this medicine.
LUNGS
ENTALIV 0.5MG should be taken with caution in patients with lung disease. Consult your doctor for advice.
INTERACTIONS
Inform your doctor about all the medicines you use, including prescription and non-prescription medicines and herbal supplements.
SYNOPSIS
| Drug | : | Entecavir |
| Pharmacological Category | : | Antiviral drug |
| Therapeutic Indication | : | Chronic infection with hepatitis B virus (HBV) |
| Dosage Forms | : | Tablet |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT ENTALIV 0.5MG
Can ENTALIV 0.5MG be used in pregnant women?
No. This medicine is not recommended for use in pregnant women. Consult your doctor before taking this medicine.
How do you take ENTALIV 0.5MG?
Take ENTALIV 0.5MG on an empty stomach, at least 2 hours before or 2 hours after eating.
Can I drive while taking ENTALIV 0.5MG?
You may experience dizziness, tiredness and sleepiness which may impair your ability to drive and use machines while taking this medicine. Consult your doctor for advice.
REFERENCES
1. Evangelini Dimou, Vasilios Papadimitropoulos, and Stephanos J Hadziyannis; The role of entecavir in the treatment of chronic hepatitis B; [Published on 2007] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387288/
2. S James Matthews; Entecavir for the treatment of chronic hepatitis B virus infection; [Published on 2006] https://pubmed.ncbi.nlm.nih.gov/16678641/
3. Goodman and Gilman’s: The Pharmacological Basis of Therapeutics. Chapter – 58, Antiviral agents; 12th ed. New York, New York: McGraw-Hill Medical, 2011. Page – 1615 - 1616.
4. Dr. Reddy’s Laboratories (UK) Ltd; Electronic Medicines Compendium (EMC); [Revised on 04/2017] [Accessed 07 Oct 2020] https://www.medicines.org.uk/emc/files/pil.2536.pdf
5. Bristol-Myers Squibb Company; U.S. Food & Drug Administration; [Revised on 11/2019] [Accessed 07 Oct 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021797s001,021798s001lbl.pdf
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