INTRODUCTION

ENTALIV 0.5MG TABLET contains Entecavir which belongs to the group of medicines called Antiviral agents. It is used to treat chronic Hepatitis-B infection in adults, children, and adolescents (2-18 years old). Hepatitis B is a viral infection that attacks the liver and can cause both acute and chronic disease.

Prior to the treatment, your doctor may want you to take several blood tests to understand your existing condition.

Before taking ENTALIV 0.5MG TABLET, inform your doctor if you have any liver, kidney or heart disease, or HIV infection.

ENTALIV 0.5MG TABLET is not recommended for use in pregnant and breastfeeding women. Consult your doctor before taking it.

ENTALIV 0.5MG TABLET is not recommended for use in children (less than 2 years of age). Consult your doctor before taking it.

The most common side effects of taking ENTALIV 0.5MG TABLET are headache, inability to sleep, extreme tiredness, dizziness, sleepiness, vomiting, diarrhoea, nausea, or indigestion. Inform your doctor if any of these side effects gets worse.

USES OF ENTALIV 0.5MG TABLET

• Used to treat chronic Hepatitis-B infection

HOW ENTALIV 0.5MG TABLET WORKS

ENTALIV 0.5MG TABLET prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up the infection.

DIRECTIONS FOR USE

Take ENTALIV 0.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF ENTALIV 0.5MG TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea or Vomiting:

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy food. Get adequate rest. Drink lots of fluids, especially water. Have small sips if you feel sick. Do not take any medicine without asking your doctor.

Headache:

Drink ample amount of water. Get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache.

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking ENTALIV 0.5MG TABLET, inform your doctor if you have taken, or might take any other medicine, including prescription, non-prescription or any herbal medicine.

Overdosage:

If you or anyone else accidentally takes too much of ENTALIV 0.5MG TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep ENTALIV 0.5MG TABLET out of reach of children
• Do not store above 30°C

FAQs ABOUT ENTALIV 0.5MG TABLET

Is ENTALIV 0.5MG TABLET safe in pregnancy?

It has not been demonstrated if ENTALIV 0.5MG TABLET is safe to use during pregnancy, so inform your doctor if you are pregnant or planning to get pregnant. It is important that women of childbearing age being treated with ENTALIV 0.5MG TABLET should use an effective method of contraception to avoid becoming pregnant.

Can ENTALIV 0.5MG TABLET cause diarrhea?

Yes. Diarrhea is a common side effect of ENTALIV 0.5MG TABLET. Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. If you experience persistent diarrhea, consult your doctor.

What if I forget to take a dose of ENTALIV 0.5MG TABLET?

If you forget to take a dose, take it as soon as you remember and then continue your treatment as usual. Do not take the medicine twice to make up for the forgotten dose. It is important to take ENTALIV 0.5MG TABLET regularly, because if you take it at irregular intervals, you may be more likely to have a hypersensitivity reaction.

Can I stop taking ENTALIV 0.5MG TABLET?

Do not stop taking ENTALIV 0.5MG TABLET without consulting your doctor. Some people may get very serious symptoms of hepatitis when they stop taking this medicine. Inform your doctor immediately if you experience any changes in symptoms after stopping this treatment. Even after your treatment with ENTALIV 0.5MG TABLET is stopped, your doctor will continue to monitor you and take blood tests.

Can ENTALIV 0.5MG TABLET cause any serious side effects?

ENTALIV 0.5MG TABLET can cause rare but serious side effects like lactic acidosis (excess of lactic acid in your blood) and enlargement of the liver, that might occasionally be fatal. Symptoms such as nausea, vomiting and stomach pain might indicate the development of lactic acidosis. It occurs more often in overweight women. Your doctor will monitor you regularly while you are receiving treatment with this medicine.

REFERENCES

1. G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Hepatitis, viral. Pharmacotherapy Handbook. Ninth edition. Page- 214.

2. Medis International. A.S. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 7th May 2022] https://www.medicines.org.uk/emc/files/pil.9874.pdf

3. Entecavir. Drugbank. [Accessed on 7th May 2022] https://go.drugbank.com/drugs/DB00442

USEFUL DIAGNOSTIC TESTS

• Liver Function Test
• Complete Blood Count (CBC)