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Dysliptin EZ Tablet 10'S
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INTRODUCTION
DYSLIPTIN EZ TABLET is a combination of Atorvastatin and Ezetimibe which belongs to the group of medicines called Anti-hyperlipidemic agents. It is used for the treatment of patients with primary hypercholesterolemia (high amounts of cholesterol in the blood). It is used along with a proper diet to lower bad cholesterol and fats (LDL, triglycerides) and raise good cholesterol (HDL) in the blood.
High cholesterol is when you have too much of a fatty substance called cholesterol in your blood. Cholesterol is a type of fat (or lipid) in the blood. Having high levels of fats in the blood can lead to serious health problems such as heart disease.
Regular monitoring of blood sugar levels, and liver function is recommended while taking this DYSLIPTIN EZ TABLET.
Before taking DYSLIPTIN EZ TABLET, inform your doctor if you have any kidney or liver problems or heart problems or high blood pressure.
Pregnant and breastfeeding women should consult their doctor before taking this medicine.
The most common side effects of taking DYSLIPTIN EZ TABLET are joint pain, diarrhoea, tendon problems, memory loss, confusion, depression, muscle and body pain. Contact your doctor if any of the above symptoms worsen.
USES OF DYSLIPTIN EZ TABLET
- Used along with a proper diet to help lower bad cholesterol and fats (such as LDL, triglycerides) and raise good cholesterol (HDL) in the blood
HOW DYSLIPTIN EZ TABLET WORKS
DYSLIPTIN EZ TABLET is a combination of Atorvastatin and Ezetimibe where Atorvastatin works by preventing your body from making bad cholesterol (LDL) while raising good cholesterol (HDL) levels. Ezetimibe works by preventing absorption of cholesterol from the intestines. Together, they provide better reduction of cholesterol in your body.
DIRECTIONS FOR USE
Take DYSLIPTIN EZ TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF DYSLIPTIN EZ TABLET
COMMON
- muscle and body pain
- diarrhoea
- joint pain
- tendon problems
- memory loss
- confusion
- depression
RARE
Stop taking DYSLIPTIN EZ TABLET and contact your doctor immediately if you experience any of the following side effects:
- serious allergic reactions symptoms such as swelling of the face, lips, tongue, and/or throat that may cause difficultyin breathing or swallowing,rash, itching,severe dizziness, trouble breathing
- muscle problems such as rhabdomyolysis and autoimmune myopathy (symptoms such as unexplained muscle pain, tenderness, or weakness, especially fever or feel more tired than usual
- liver problems symptoms such as feel tired or weak, loss of appetite, upper belly pain, dark urine, yellowing of your skin or the whites of your eyes, severe stomach pain, persistent nausea, or vomiting.
- kidney problems symptoms such as change in the amount of urine
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhoea. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS
PREGNANCY
DYSLIPTIN EZ TABLET is not recommended for use in pregnant women. Consult your doctor before taking this medicine.
BREASTFEEDING
DYSLIPTIN EZ TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking this medicine.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizziness after taking DYSLIPTIN EZ TABLET.
ALCOHOL
Consumption of alcohol is not recommended during treatment with this DYSLIPTIN EZ TABLET because it can increase the risk of liver problems.
KIDNEY
DYSLIPTIN EZ TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking this medicine.
LIVER
DYSLIPTIN EZ TABLET is not recommended for use in patients with active liver disease.Consult your doctor before taking this medicine.
ALLERGY
Do not take DYSLIPTIN EZ TABLET if you are allergic to Atorvastatin, Ezetimibe or any other ingredients of this medicine.
OTHERS
Before taking DYSLIPTIN EZ TABLET, inform your doctor if you have:
- thyroid problems
- diabetes
- unexplained muscle aches or weakness
- any other medical conditions
Use in pediatrics:
DYSLIPTIN EZ TABLET is not recommended for use in children less than 6 years of age, because there is no information in this age group. Consult your doctor before taking this medicine.
Use in geriatrics:
DYSLIPTIN EZ TABLET should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking this medicine.
INTERACTIONS
A. Drug-Drug interactions:
Before taking DYSLIPTIN EZ TABLET, inform your doctor if you are taking any of the following medicine:
- cholestyramine, colestipol, gemfibrozil (used to treat cholesterol)
- daptomycin,telithromycin (used to treat infections)
- medicines used for birth control
- medicines used to treat heart failure
- ritonavir (used to treat HIV or AIDS)
- glecaprevir, pibrentasvir, telaprevir (used to treat hepatitis C)
- medicines used to treat gout
- cyclosporine (used to prevent organ rejection)
B. Drug - Food interaction:
Avoid grapefruit or grapefruit juice or red yeast rice while taking DYSLIPTIN EZ TABLET as it may increase the risk of side effects.
Overdosage:
If you or anyone else accidentally takes too much of DYSLIPTIN EZ TABLET, consult your doctor immediately.
SYNOPSIS
| Drug | : | Atorvastatin, Ezetimibe |
| Pharmacological Category | : | HMG-CoA reductase inhibitors, Cholesterol-lowering medications |
| Therapeutic Indication | : | Treats hypercholesterolemia |
| Dosage Forms | : | Tablet, Capsule |
MORE INFORMATION
- Keep DYSLIPTIN EZ TABLET out of reach of children
- Store at room temperature
FAQs ABOUT DYSLIPTIN EZ TABLET
Can I consume alcohol while taking [GBBNKEYWORD]?
No, avoid consumption of alcohol while taking this medicine. Follow the lifestyle modification suggested by your doctor such as quitting smoking or alcohol consumption during this therapy to achieve better results.
Will taking [GBBNKEYWORD] increase the risk of diabetes?
[GBBNKEYWORD] may raise your blood sugar a little. If you already have type 2 diabetes, consult your doctor. Your doctor may adjust the dosage of this medicine.
Is DYSLIPTIN EZ TABLET effective?
Yes, it is effective if used in the dose and duration directed by your physician. Consult your doctor for advice.
Is there any lifestyle help for reducing bad cholesterol in our blood?
Increase your daily diet with fibre, fruits, vegetables, whole grains, fish, and cut saturated fat as well. Stop smoking and drinking and try to work out every day as well.
Can I take DYSLIPTIN EZ TABLET during liver disease?
No, it is not recommended for use in patients with active liver disease. Consult your doctor before taking this medicine.
Can DYSLIPTIN EZ TABLET cause diarrhoea?
Yes, this DYSLIPTIN EZ TABLET may cause diarrhoea in some individuals. Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhoea. Consult your doctor if the symptom did not improve.
REFERENCES
1. KD. Tripathi. Hypolipidaemic Drugs andPlasma Expanders. Essentials of medical pharmacology. Seventh edition. 2013. Page – 637& 641.
2. A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants with High Cholesterol (MK-0653C-190 AM1). NIH: U.S. National Library of Medicine.ClinicalTrials.gov.9 Feb 2022 [Accessed on 11 Apr 2022] https://clinicaltrials.gov/ct2/show/NCT01370603
3. Christie M Ballantyne, John Houri, Alberto Notarbartolo, Lorenzo Melani, Leslie J Lipka, Ramachandran Suresh, Steven Sun, Alexandre P LeBeaut, Philip T Sager, Enrico P Veltri, Ezetimibe Study Group.Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial.NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 20 May 2003.[Accessed on 11 Apr 2022] https://pubmed.ncbi.nlm.nih.gov/12719279/
4. Webmd.com.atorvastatin-ezetimibe tablet [Accessed on 11 Apr 2022] https://www.webmd.com/drugs/2/drug-164168/ezetimibe-atorvastatin-oral/details
5. Merck & Co., Inc, 2013; U.S. Food & Drug Administration; [Revised on May 2014] [Accessed on 11 Apr 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/200153s003lbl.pdf
USEFUL DIAGNOSTIC TESTS
- Cholesterol - HDL
- Cholesterol - LDL
- Cholesterol – Total
AUTHOR DETAILS
Written By Dr. Janet.C, Pharm.D
Last updated on 26 Oct 2022 | 02:45 PM(IST)
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