Duron 150mg Injection 3ml

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What is DURON 150mg?

  • DURON 150mg contains active ingredient Amiodarone which belongs to a group of medicines called anti-arrhythmics
  • It works by controlling the uneven beating of your heart called arrhythmias







What DURON 150mg is used for?

DURON 150mg is used in the treatment of:

  • uneven heartbeats
  • other types of fast or uneven heartbeats known as atrial flutter, atrial fibrillation
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Talk to your doctor before taking this medicine, if you,

  • have an allergy to DURON 150mg, iodine, or any of the other ingredients in DURON 150mg Tablets
  • have certain heart conditions (heart block, very slow heart rate, or slow heart rate with dizziness or lightheadedness)
  • have any other problems with your heartbeat and do not have a pacemaker fitted
  • have thyroid problems
  • have lung problems
  • have any problems with your eyesight
  • have an operation
  • are receiving high dose oxygen therapy
  • are due to have an operation involving general anesthesia
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  • If you are pregnant or planning to become pregnant talk with your doctor
  • You should not breastfeed while taking DURON 150mg
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  • The child’s doctor will calculate the amount of DURON 150mg depending on the child’s body weight
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  • DURON 150mg may make it unsafe for you to drive or operate machinery, you must speak to your doctor or nurse
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Tell your doctor about all the medicines you take including prescription and nonprescription medicines, vitamins and herbal supplements.

  • Quinidine, procainamide, disopyramide and sotalol medicine used to treat heart rhythms
  • Erythromycin, co-trimoxazole and pentamidine used to treat infections
  • chlorpromazine, haloperidol and pimozide medicines used  to treat mental illness
  • Medicines to treat depression, such as lithium and tricyclic antidepressants, including doxepin, and amitriptyline
  • Terfenadine, astemizole,medicines to treat allergic reaction
  • Medicines used to treat or prevent malaria, such as quinine, mefloquine, chloroquine
  • Oral anticoagulants e.g. warfarin (used to thin the blood)
  • phenytoin (used to treat epilepsy)
  • digoxin (used to treat certain heart conditions)
  • Stimulant laxatives such as bisacodyl and senna, medicines called diuretics or water tablets
  • steroids and the antifungal medicine amphotericin
  • Rifampicin (an antibiotic)
  • John’s Wort (a herbal medicine)
  • Cyclosporin, tacrolimus (immunosuppressants)
  • Simvastatin and atorvastatin (drugs to reduce blood cholesterol)
  • Lidocaine (a local anaesthetic)
  • Sildenafil (used for erectile dysfunction)
  • Fentanyl (used for pain relief)
  • Midazolam (a sedative)
  • Ergotamine (for migraine)
  • Beta-blockers, such as metoptolol, sotalol and bretylium
  • Calcium channel blockers diltiazem and verapamil, used to treat high blood pressure
  • Indinavir (an anti-viral drug)
  • Dextromethorphan (cough medicine)
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  • Your doctor or nurse will normally give you DURON 150mg. It needs to be given as an infusion into your vein in the hospital where the doctor can monitor your progress
  • This medicine will be diluted before it is given to you
  • The recommended dose is 5 mg for every kilogram of your bodyweight. This is given by intravenous infusion over a period of 20 minutes to 2 hours
  • You may be given another infusion of approximately 15 mg for every kilogram of your bodyweight every 24 hours depending on your illness
  • In an emergency, your doctor may decide to give you a dose of 150 mg to 300 mg as a slow injection over 3 minutes 
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Like all medicines, this medicine can cause side effects, although not everybody gets them.





  • severe allergic reactions: swelling of hands, feet, lips, mouth, tongue or throat
  • difficulty in breathing
  • itchy skin rash (hives)
  • diarrhoea
  • stomach pains
  • excessive thyroid activity (hyperthyroidism): weight loss, weakness, restlessness
  • irregular heart rate, heart failure
  • rhabdomylosis marked by muscle pain, tenderness, weakness or cramps
  • breakdown of muscle tissue causing kidney damage, which may lead to swelling of the hands or feet, shortness of breath, darker urine than normal and abnormal blood test results
  • vision problems that may lead to permanent blindness.
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  • nausea, vomiting, constipation, and loss of appetite
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  • muscle cramps, stiffness or spasm
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  • swelling of the testicles
  • lung, liver or thyroid problems
  • heart or eye problems
  • red, scaly patches of skin, loss of hair or loosening of nails
  • feeling tired, faint, dizzy or having pale skin. these could be signs of anemia
  • you may bleed or bruise more easily than usual. this could be because of a blood disorder (called ‘thrombocytopenia’)
  • feeling unwell, confused or weak, nausea, loss of appetite, feeling irritable, this could be an illness called ‘syndrome of inappropriate anti-diuretic hormone secretion’
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  • Store at room temperature (15-25°C)
  • Keep DURON 150mg out of sight and reach of children protected from sunlight
  • Do not use this medicine after the expiry date
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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