Duron 150mg Injection 3ml

Arrhythmiasis Rx required

Best Price* ₹ 65.79 MRP ₹ 73.10
(Inclusive of all taxes) * Mkt: Samarth Life Sciences Pvt Ltd * Country of Origin: NA * Delivery charges if applicable will be applied at checkout

Check Availability & Expiry

PINCODE:


INTRODUCTION

DURON 150MG INJECTION contains Amiodarone which belongs to the group of medicines called Antiarrhythmics. It is used to treat uneven or fast heartbeats (like atrial flutter or atrial fibrillation), fast heartbeats which may happen suddenly and may be uneven only when other medicines either have not worked or cannot be used.

It also treats Wolff-Parkinson-White Syndrome (unusually fast heartbeats). It is normally only given in a hospital when a quick response is needed or when tablets cannot be given.

Your doctor might want you to keep out of direct sunlight while receiving DURON 150MG INJECTION and for a few months after you have finished receiving it. Avoid consumption of alcohol and grapefruit juice during treatment with DURON 150MG INJECTION.

DURON 150MG INJECTION is not recommended for use if you have severe breathing and blood circulation problems, slower than usual heartbeat (called ‘sinus bradycardia’) or an illness called sino-atrial heart block.

It is also not recommended if you have other problems with your heartbeat without a pacemaker fitted, are going to have a heart transplantation, have ever had thyroid problems or low blood pressure.

Before receiving DURON 150MG INJECTION, inform your doctor if you have heart failure or weak heart (cardiomyopathy), liver, kidney, thyroid, lung problems or asthma, require oxygen treatment, are to undergo a general anesthetic, or have eyesight problems (optic neuritis).

Also inform your doctor if you are about to have any surgery, blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, flu-like symptoms and fever (Stevens-Johnson syndrome), layers of the skin skin peeling off to leave large areas of raw exposed skin over the body (Toxic Epidermal Necrolysis).

DURON 150MG INJECTION is not recommended for pregnant or breastfeeding women. DURON 150MG INJECTION is contraindicated in premature babies or neonates and should be used with caution in infants and children up to 3 years old. Safety data has not been established in children and adolescents above 3 years of age.

DURON 150MG INJECTION should be used with caution in elderly patients above 60 years of age. The most common side effects of receiving DURON 150MG INJECTION are blurred eyesight, rashes, muscle weakness, difficulty sleeping, nightmares. Consult your doctor if any of the symptoms worsen.

USES OF DURON 150MG INJECTION

It is usually used in hospitals when tablets cannot be given and a quick response is needed to treat:

  • sudden fast or uneven heartbeats (atrial flutter or atrial fibrillation) when other medicines either have not worked or cannot be used
  • Wolff-Parkinson-White Syndrome

HOW DURON 150MG INJECTION WORKS

DURON 150MG INJECTION works by blocking certain electrical signals and reducing the excitability of cardiac tissues which prevents the initiation and conduction of any new impulses in the heart that cause irregular heartbeats, thus making your heartbeat return to normal.

DIRECTIONS FOR USE

DURON 150MG INJECTION must be given by a doctor or nurse into the vein as an intravenous injection or infusion. Your doctor will decide the correct dose and duration of DURON 150MG INJECTION for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF DURON 150MG INJECTION

COMMON

  • blurred eyesight or seeing a colorful halo in dazzling light
  • tanning more easily in the sun
  • red rash with itching
  • slightly slower heartbeat, reduced blood pressure (dizziness, light-headedness, fainting)
  • reactions at injection site (swelling, pain, redness, infection, blue or gray marks on parts of your skin exposed to sunlight, especially the face)
  • hyperthyroidism (feeling extremely restless or agitated, weight loss, too much sweating and unbearable heat)
  • hypothyroidism (feeling extremely tired or weak, weight gain, unbearable cold, constipation and muscle pain)
  • shivering when you move your arms or legs, weak muscles
  • nightmares, sleep problems
  • reduced sex drive

UNCOMMON

  • numbness, weakness, tingling or burning feelings in any part of your body

RARE

  • hypersensitivity reactions (due to an excipient- benzyl alcohol)

Stop receiving DURON 150MG INJECTION and consult your doctor immediately if you experience any of the following side effects:

  • allergic reaction (rash, difficulty swallowing or breathing, swollen eyelids, face, lips, throat or tongue)
  • very slow or no heartbeats (dizziness, tiredness, breathlessness)
  • more uneven or unstable heartbeats (can lead to heart attack)
  • liver problems or damage (yellowing of the skin or eyes, tiredness, nausea, loss of appetite, stomach pain or fever)
  • lung inflammation (breathlessness or tightness in the chest, coughing which will not go away, wheezing or weight loss)
  • torsade de pointes (life-threatening irregular heartbeat)
  • Stevens-Johnson syndrome (blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, and flu-like symptoms)
  • toxic epidermal necrolysis (severe blistering rash in which layers of the skin may peel off, feeling generally unwell, chills and muscle pain)
  • bullous dermatitis (fluid filled blisters on the skin)
  • problem with your brain (headache (usually worse in the morning or happens after coughing or straining), nausea, fits, confusion))
  • flu like symptoms and a rash on the face followed by an extended rash with a high temperature, enlarged lymph nodes (DRESS)

HOW TO MANAGE SIDE EFFECTS

Dizziness, Fainting:

When you start receiving DURON 150MG INJECTION, you may feel faint or dizzy. This is caused by your blood pressure dropping. If this happens, resting or lying down for some time can help. Consult your doctor if symptoms don't improve.

Rash:

Applying a cold compress, cool showers or damp cloth, cold water can bring immediate relief to swelling and reduce itching. Consult your doctor if symptoms don't improve.

Muscle pain:

Hot compress helps to increase blood flow, which relaxes sore muscles and joints and reduces pain. Cold compress can reduce inflammation around the aching muscle or joint. Consult your doctor if symptoms don't improve.

WARNING & PRECAUTIONS

PREGNANCY

DURON 150MG INJECTION is not recommended for use in pregnant women or women planning to have a baby, except in life-threatening circumstances. Consult your doctor before receiving it.

BREASTFEEDING

DURON 150MG INJECTION is not recommended for use in breastfeeding women. Consult your doctor before receiving it.

DRIVING AND USING MACHINES

DURON 150MG INJECTION may affect your ability to drive or use machines. Consult your doctor before receiving it.

ALCOHOL

Limit the consumption of alcohol during treatment with DURON 150MG INJECTION. Consult your doctor before receiving it.

KIDNEY

DURON 150MG INJECTION should be received with caution in patients with kidney problems. Consult your doctor before receiving DURON 150MG INJECTION.

LIVER

DURON 150MG INJECTION should be received with caution in patients with liver problems. Consult your doctor before receiving it.

ALLERGY

Do not receive DURON 150MG INJECTION if you are allergic to Amiodarone or any of the other ingredients of this medicine. Consult your doctor before receiving it.

LUNGS

DURON 150MG INJECTION is not recommended for use if you have severe breathing problems. DURON 150MG INJECTION should be received with caution in patients with asthma, or any other lung diseases. Consult your doctor before receiving it.

HEART DISEASE

DURON 150MG INJECTION should not be given in patients with slower than usual heartbeat (called ‘sinus bradycardia’) or an illness called sino-atrial heart block, other problems with your heartbeat without a pacemaker fitted, are going to have a heart transplantation or have low blood pressure.

DURON 150MG INJECTION should be used cautiously in patients with heart failure or weak heart (cardiomyopathy) or low blood pressure. Consult your doctor before receiving DURON 150MG INJECTION.

OTHERS

DURON 150MG INJECTION is not recommended for use if you:

  • have or have earlier had any thyroid problems
  • have blood circulation problems

Before receiving DURON 150MG INJECTION, inform your doctor if you:

  • have any issues with your eyesight (optic neuritis)
  • are about to have any surgery
  • have Stevens-Johnson syndrome (blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, flu-like symptoms and fever)
  • have toxic epidermal necrolysis (severe blistering rash in which layers of the skin may peel off, feeling generally unwell, fever, chills and muscle pain)
  • require oxygen treatment or are to undergo a general anesthetic
  • have thyroid problems

Use in pediatrics:

DURON 150MG INJECTION is contraindicated in premature babies or neonates and should be used with caution in infants and children up to 3 years old.

Safety data has not been established in children and adolescents above 3 years of age.

Use in geriatrics:

DURON 150MG INJECTION should be used with caution in elderly patients aged above 60 years. Consult your doctor before receiving DURON 150MG INJECTION.

INTERACTIONS

A. Drug - Drug interactions:

Before receiving DURON 150MG INJECTION, inform your doctor if you are taking any of the following medicine:

  • other medicines used to treat uneven heartbeats (Ex. sotalol, quinidine, procainamide, disopyramide, flecainide, bretylium or amiodarone tablets)
  • medicines used to improve blood supply to the brain (Ex. vincamine).
  • medicines used to treat other mental illnesses like depression (Ex. sultopride, sulpiride, pimozide, lithium, doxepin, maprotiline, amitriptyline, clomipramine, dosulepin, imipramine, lofepramine, nortriptyline or trimipramine)
  • medicines used to treat infections (Ex. intra-venous erythromycin, co-trimoxazole, moxifloxacin, pentamidine, clarithromycin, ciprofloxacin, ofloxacin, levofloxacin or injections of pentamide)
  • medicines used to treat schizophrenia (Ex. chlorpromazine, fluphenazine, thioridazine, haloperidol, sertindole or amisulpride)
  • medicines used to treat hay fever, rashes or other allergies (Ex. terfenadine, astemizole or mizolastine)
  • medicines used to treat malaria (Ex. quinine, mefloquine, chloroquine or halofantrine)
  • medicines used to treat hepatitis C (Ex. sofosbuvir, daclatasvir, simeprevir or ledispasvir)
  • medicine used to treat heart problems (such as high blood pressure, chest pain or high cholesterol) (Ex. propranolol, flecainide, diltiazem, verapamil, furosemide, simvastatin, atorvastatin or digitalis)
  • medicines used to treat digestive problems like constipation (Ex. cisapride, droperidol, bisacodyl or senna)
  • medicines used to treat fungal infection (Ex. amphotericin IV)
  • medicines used to treat inflammation (Ex. hydrocortisone, betamethasone or prednisolone)
  • medicines which may change the levels of potassium or magnesium in your blood Ex. diuretics (water tablets), steroid tablets
  • medicines for high cholesterol called statins (e.g. simvastatin or atorvastatin).
  • medicines used to treat fits (Ex. phenytoin)
  • medicines used during surgery (Ex. lidocaine, midazolam, triazolam or high dose oxygen)
  • medicines used to test some hormone problems (Ex. tetracosactide)
  • medicines used to prevent rejection of transplants (Ex. ciclosporin, tacrolimus and sirolimus)
  • medicines used to treat erection problems (Ex. sildenafil, tadalafil or vardenafil)
  • medicines used to treat pain or migraines (Ex. fentanyl or ergotamine)
  • medicines used to stop your blood from clotting (Ex. warfarin, dabigatran)
  • medicine used in some blood tests or in treatment of Crohn’s disease (Ex. tetracosactrin)

B. Drug - Food interaction:

Avoid drinking grapefruit juice while receiving DURON 150MG INJECTION as it may increase the risk of side effects.

Overdosage:

DURON 150MG INJECTION will be given to you only by a doctor or nurse in a hospital and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms like feeling dizzy, faint, sick, tired, confused or abnormally slow or fast heartbeats, contact your doctor immediately.

SYNOPSIS

Drug :   Amiodarone
Pharmacological Category :   Antiarrhythmic
Therapeutic Indication :   Arrhythmias, Wolff-Parkinson-White Syndrome
Dosage Forms :   Tablet, Injection

MORE INFORMATION

  • Keep DURON 150MG INJECTION out of reach of children
  • Do not store above 25°C

FAQs ABOUT DURON 150MG INJECTION

What is DURON 150MG INJECTION used for?

DURON 150MG INJECTION is used to treat uneven or fast heartbeats (like atrial flutter or atrial fibrillation), fast heartbeats which may happen suddenly and may be uneven only when other medicines either have not worked or cannot be used. It also treats Wolff-Parkinson-White Syndrome (unusually fast heartbeats).

 How does DURON 150MG INJECTION work?

DURON 150MG INJECTION works by blocking certain electrical signals and reducing the excitability of cardiac tissues which prevents the initiation and conduction of any new impulses in the heart that cause irregular heartbeats, thus making your heartbeat return to normal.

Can DURON 150MG INJECTION make my skin sensitive to the sun?

Yes. your skin will become much more sensitive to the sun after receiving DURON 150MG INJECTION and may burn, tingle or severely blister. Do not expose yourself to direct sunlight while receiving this medicine and for a few months after you have finished receiving it. Use high factor sun cream without fail. Always wear a hat and clothes which cover your whole body.

What should I avoid while receiving DURON 150MG INJECTION?

Avoid drinking grapefruit juice while receiving DURON 150MG INJECTION as it may increase the risk of side effects. Avoid consumption of alcohol during treatment with DURON 150MG INJECTION, as it may increase the chances of liver problems.

Will DURON 150MG INJECTION cause any reaction at the site of injection?

DURON 150MG INJECTION may cause swelling, pain, redness, infection and blue or grey marks on parts of your skin exposed to sunlight, especially the face. You can apply cold compress for relief. Consult your doctor before using any product for the reaction, other than DURON 150MG INJECTION.

REFERENCES

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Arrhythmias. Pharmacotherapy handbook. Ninth edition. Page- 48, 49.

2. KD. Tripathi. Antiarrhythmic Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 533.

3. HBM Pharma. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 20th April 2022] https://www.medicines.org.uk/emc/files/pil.3940.pdf, https://www.medicines.org.uk/emc/product/3940/smpc

4. Bioindustria Laboratorio Medicinali S.p.A. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 20th April 2022] https://www.medicines.org.uk/emc/files/pil.8739.pdf

USEFUL DIAGNOSTIC TESTS

  • Liver Function Test (LFT)
  • Thyroid Function Test (TFT)
  • Complete Blood Count (CBC)
  • Chest X-Ray
  • Electrocardiogram (ECG)

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    15 g
    Ingredient
    AMIODARONE 150MG
    Hsn Code
    30049079
ALTERNATE BRANDS
Amiodon 150mg Injection 3ml
Prescription Heart Failure Rx required
Rs.72.30
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Duron 150mg Injection 3ml

Duron 150mg Injection 3ml Mkt: Samarth Life Sciences Pvt Ltd

M.R.P.: Rs.73.10
Copyright© 2023. All Rights Reserved.