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Introduction About DAPMICIN 350MG INJECTION
DAPMICIN 350MG INJECTION contains Daptomycin which belongs to the group of medicines called Antibiotics. It is used to manage bacterial infections of the skin and soft tissues, blood and tissues covering the heart. It is suitable for use both in adults and in children (aged between 1-17 years).
DAPMICIN 350MG INJECTION should be used under medical supervision. Do not stop receiving this medicine even if you feel better during the midway of the therapy. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control.
Before receiving DAPMICIN 350MG INJECTION inform your doctor if you have any kidney problems or muscle problems as a precaution. DAPMICIN 350MG INJECTION is generally not recommend for use in pregnant or breastfeeding women.
The most common side effects of receiving DAPMICIN 350MG INJECTION are nausea, vomiting, headache, dizziness, pain and redness at the site of injection, urinary tract infection, increased fungal infections, anemia, constipation and pain in arms or legs. Inform your doctor if they trouble you.
Uses Of DAPMICIN 350MG INJECTION
It is used to manage the following bacterial infections:
- Skin or soft tissue infections (Ex. cellulitis, erysipelas, impetigo, folliculitis, and furuncles and carbuncles)
- Blood infections (Ex. sepsis)
- Pericarditis (infections of tissues surrounding the heart)
How DAPMICIN 350MG INJECTION Works
DAPMICIN 350MG INJECTION is a powerful antibacterial agent. It kills the susceptible bacteria by disrupting the bacterial cell wall. This manages further bacterial growth and reduces the severity of the infection.
How to use DAPMICIN 350MG INJECTION
DAPMICIN 350MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously).
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.
Do not miss a dose or stop receiving DAPMICIN 350MG INJECTION without consulting your doctor as it may worsen your condition.
Side Effects Of DAPMICIN 350MG INJECTION
Common
- fungal infections (such as thrush)
- urinary tract infection
- low RBC count in blood (anaemia)
- headache, dizziness, anxiety, difficulty in sleeping
- fever, weakness
- high or low blood pressure
- constipation, stomach pain, diarrhoea, nausea, vomiting, bloating
- abdominal swelling or bloating
- skin rash or itching
- injection site reactions (such as pain, redness or itching)
- arm pain, leg pain
- higher levels of liver enzymes or creatine phosphokinase (CPK)
Uncommon
- increase in WBC or platelet count in blood
- decreased appetite
- tingling or numbness of hands and feet
- taste disturbances
- abnormal heart rhythm
- hot flushes
- inflammation of the tongue
- joint pain, tiredness
- inflammation and irritation of the vagina
- increase in blood sugar levels
- itchy eyes
Rare
- yellowing of the skin and eyes
- increased bleeding time
Contact your doctor immediately if you experience any of the following side effects:
- signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing)
- severe muscle weakness, tenderness or pain
- severe persistent diarrhea with blood or mucus
- signs of eosinophilic pneumonia (such as difficulty in breathing, new or worsening cough, or new or worsening fever)
- severe skin reactions (such as skin rash with appears as red raised fluid filled spots under the armpits, chest or groin, blisters in mouth or genitals with fever)
How To Manage Side Effects
Diarrhea
Drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens, contact your doctor immediately.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely if you feel dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Consult your doctor if your headache worsens.
Nausea And Vomiting
Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor immediately if your symptom does not improve.
Skin rash Or Itching
Avoid taking hot showers, as it may further irritate your skin. Use protective clothes while going outdoors. Avoid scratching the affected area of the skin. Regularly moisturize your skin. Consult your doctor if your condition worsens.
Warning & Precautions
Pregnancy
ContraindicatedDAPMICIN 350MG INJECTION is generally not recommended for use in pregnant women. Therefore, consult your doctor before receiving it.
Breastfeeding
ContraindicatedDAPMICIN 350MG INJECTION is generally not recommended for use in breastfeeding women. Therefore, consult your doctor before receiving it.
Driving and Using Machines
Use with CautionDAPMICIN 350MG INJECTION is unlikely to affect your ability to drive or operate any heavy tools or machines.
Kidney
Use with CautionDAPMICIN 350MG INJECTION should be used with caution in patients suffering from kidney problems. Therefore, consult your doctor before receiving it.
Allergy
ContraindicatedTalk to your doctor before receiving DAPMICIN 350MG INJECTION if you are allergic to Daptomycin.
Use In Pediatrics
Monitoring requiredDAPMICIN 350MG INJECTION can be used in children and adolescents (aged between 1-17 years) if prescribed by the physician. However, consult your doctor for advice.
Use In Geriatrics
Use with CautionDAPMICIN 350MG INJECTION should be used with caution in the elderly patients. Therefore, consult your doctor for advice before receiving it.
Others
Before receiving DAPMICIN 350MG INJECTION, inform your doctor if you:
- are overweight
- are going to have a lab test
- have muscle problems
Interactions
A. Drug-Drug interactions:
Before receiving DAPMICIN 350MG INJECTION, inform your doctor if you are taking any of the following medicine:
- Antihyperlipidemic agents (such as atorvastatin, rosuvastatin, fenofibrate)
- ciclosporin (a medicine used to suppress immune system and manages graft rejection)
- pain-relieving medicines (such as aspirin, diclofenac, celecoxib)
- oral anticoagulants (used for blood thinning) such as warfarin
Overdosage:
DAPMICIN 350MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
Synopsis
| Drug | : | Daptomycin |
| Pharmacological Category | : | Cyclic Lipopetide Antibiotics |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Injection |
More Information
Storage
- Keep DAPMICIN 350MG INJECTION out of reach of children
- Store DAPMICIN 350MG INJECTION in a refrigerator between 2-8°C
FAQs About DAPMICIN 350MG INJECTION
Q: What is the use of DAPMICIN 350MG INJECTION?
A: DAPMICIN 350MG INJECTION is used to manage bacterial infections of the skin and soft tissues, blood and tissues covering the heart.
Q: How DAPMICIN 350MG INJECTION works in my body?
A: DAPMICIN 350MG INJECTION is a powerful antibacterial agent. It kills the susceptible bacteria by disrupting the bacterial cell wall. This manages further bacterial growth and reduces the severity of the infection.
Q: Can DAPMICIN 350MG INJECTION be used in patients with kidney problems?
A: DAPMICIN 350MG INJECTION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving it.
Q: How DAPMICIN 350MG INJECTION is administered?
A: DAPMICIN 350MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously).
Q: For how long should I take DAPMICIN 350MG INJECTION?
A: Take DAPMICIN 350MG INJECTION for the stipulated duration as prescribed by your doctor. Do not skip the medicine or stop receiving it on your own as it may cause the infection to become severe.
Q: Can DAPMICIN 350MG INJECTION be given to pregnant women?
A: DAPMICIN 350MG INJECTION is generally not recommended for use in pregnant women. Therefore, consult your doctor before receiving it.
Q: What are the common side effects of receiving DAPMICIN 350MG INJECTION?
A: The most common side effects of receiving DAPMICIN 350MG INJECTION are nausea, vomiting, headache, dizziness, pain and redness at the site of injection, urinary tract infection, increased fungal infections, anemia, constipation and pain in arms or legs. Inform your doctor if they trouble you.
Q: Can I stop receiving DAPMICIN 350MG INJECTION once my symptoms subside?
A: Do not stop receiving DAPMICIN 350MG INJECTION once your symptoms subside. It is important to take the full course of DAPMICIN 350MG INJECTION to achieve better results. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control. It may also cause your symptoms to reappear.
Q: Can the use of DAPMICIN 350MG INJECTION cause diarrhea?
A: DAPMICIN 350MG INJECTION may cause diarrhea in some individuals. If you experience diarrhea, drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens contact your doctor immediately.
Q: What kind of infections that DAPMICIN 350MG INJECTION can manage?
A: DAPMICIN 350MG INJECTION is an antibiotic. It is used to manage bacterial infections of the skin and soft tissues, blood and tissues covering the heart.
Q: Is DAPMICIN 350MG INJECTION a steroid?
A: No. DAPMICIN 350MG INJECTION is an antibiotic and not a steroid medicine.
Q: Can DAPMICIN 350MG INJECTION manage viral infections?
A: No. DAPMICIN 350MG INJECTION cannot manage viral infections. It manages only bacterial infections of skin and soft tissues, blood and tissues covering the heart. It acts by killing the susceptible bacteria which are responsible for causing infections, and therefore not effective against any viral infections.
Q: Can DAPMICIN 350MG INJECTION cause fever?
A: DAPMICIN 350MG INJECTION may cause a mild fever in some individuals. Consult your doctor if it bothers you.
References
1. Goodman & Gilman’s: The Pharmacological Basics of Therapeutics. 12th Edition. 2011. Protein Synthesis Inhibitors and Miscellaneous Antibiotic Agents. Page -1542.
2. Dr. Reddy’s Laboratories (UK) Ltd. Daptomycin 350 mg Powder for Solution for Injection/Infusion Daptomycin 500 mg Powder for Solution for Injection/Infusion daptomycin. Electronic Medicines Compendium (EMC) [Revised in May 2022] [Accessed on 10th February 2023] https://www.medicines.org.uk/emc/files/pil.9786.pdf
3. Merck & Co., Inc. Cubicin® 500 mg powder for solution for injection or infusion daptomycin. Electronic Medicines Compendium (EMC) [Revised in June 2022] [Accessed on 10th February 2023] https://www.medicines.org.uk/emc/files/pil.8124.pdf
4. Central Drugs Standard Control Organization. Daptomycin powder for concentrate for solution for infusion (350mg/500mg per vial). January 2008. [Accessed on 10th February 2023] https://cdscoonline.gov.in/CDSCO/Drugs
Useful Diagnostic Tests
- Complete Blood Count
- Peripheral Smear Examination
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