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Introduction About CEFRINE 300MG CAPSULE
CEFRINE 300MG CAPSULE is used in the management of severe forms of bacterial infections such as Community acquired pneumonia, Acute exacerbation of chronic bronchitis, Uncomplicated skin & skin structure infection, Pharyngitis, tonsillitis and sinusitis and Ear infections (such as Otitis media). It contains Cefdinir which is a third-generation cephalosporin antibiotic. It works by killing the susceptible bacteria that causes infections.
Take CEFRINE 300MG CAPSULE as advised by your physician. It can be taken with or without meals. Do not skip doses or stop taking this medicine without consulting your doctor, even if you feel better, as it could make the medicine less effective against complete eradication of the infections.
Before taking CEFRINE 300MG CAPSULE inform your doctor if you are allergic to cephalosporin antibiotics, penicillins, cefdinir or similar medicines, have a previous history of developing severe diarrhea and stomach pain after taking antibiotics, are suffering from colitis, kidney problems, or if you are pregnant or breastfeeding.
The most common side effects of taking CEFRINE 300MG CAPSULE are mild diarrhea, nausea, vomiting, headache and dizziness. Consult your doctor if they trouble you. Inform your doctor immediately if you experience severe stomach pain with blood diarrhea or fever, chills and flu-like symptoms after taking this medicine.
Uses Of CEFRINE 300MG CAPSULE
Used in the management of severe forms of bacterial infections such as:
- Community acquired pneumonia
- Acute exacerbation of chronic bronchitis
- Uncomplicated skin & skin structure infection
- Pharyngitis, tonsillitis and sinusitis
- Ear infections (such as Otitis media)
How CEFRINE 300MG CAPSULE Works
CEFRINE 300MG CAPSULE contains Cefdinir which is a powerful antibiotic. It works by binding to the bacteria cell wall and inhibiting peptidoglycan synthesis, an essential component in bacterial cells that is required to keep cell wall stronger. This action, causes lysis of bacterial cell wall, disrupting cell components, followed by inactivation of the bacteria cells. Hence, Cefdinir is effective in managing severe bacterial infections.
How to use CEFRINE 300MG CAPSULE
Take CEFRINE 300MG CAPSULE as advised by your physician. It can be taken with or without meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you based on your age, body weight and severity of infection.
Follow the dosing schedule as advised by your physician to achieve better results. Do not skip doses or stop taking this medicine without consulting your doctor, even if you feel better, as it could make the medicine less effective against complete eradication of the infections.
Side Effects Of CEFRINE 300MG CAPSULE
Common
- Nausea, vomiting
- Mild diarrhea
- Stomach pain, indigestion
- Headache, dizziness
- Diaper rash in an infant taking liquid cefdinir
- Mild itching or skin rash
- Vaginal itching or discharge
Stop taking CEFRINE 300MG CAPSULE and consult your doctor immediately if you experience any of the following side effects such as:
- Allergic reactions (such as skin rashes, itching, swelling of lips, face, throat causing difficulty in breathing or swallowing)
- Severe blistering and peeling of skin with fever, sore throat
- Bloodly diarrhea
- Chest pain, fever, chills, body aches, flu-like symptoms
- Unusual bleeding
- Seizures
- Jaundice (signs include yellowing of skin and eyes, nausea, skin itching)
- Excessive thirst
How To Manage Side Effects
Dizziness Or Drowsiness
Sit or lie down as soon as you feel dizzy to prevent falls and stay still until the sensation passes. Slowly change positions, especially when getting up from sitting or lying down, to avoid sudden drops in blood pressure. Staying hydrated is key, as dehydration can cause or worsen dizziness. Ensure you're eating regularly to maintain blood sugar levels, and avoid alcohol or caffeine, which can exacerbate dizziness. Resting in a cool, quiet environment can help, especially if the dizziness is related to stress or overheating. If dizziness persists or is accompanied by other symptoms like chest pain or severe headache, seek medical attention.
Nausea And Vomiting
Taking the antibiotic with food can help, as it can reduce stomach irritation. However, check if the specific antibiotic can be taken with food, as some require an empty stomach for proper absorption. Staying hydrated is essential; drinking small sips of water throughout the day can help ease nausea. Eating smaller, more frequent meals with bland, easy-to-digest foods like crackers, toast, or rice can also alleviate symptoms. Ginger, whether in tea or as a supplement, is known to help with nausea. If the nausea persists or worsens, it’s important to consult a healthcare provider, as they might adjust the dosage or switch to a different antibiotic.
Warning & Precautions
Pregnancy
Consult your doctorThere are no adequate results regarding the use of Cefdinir 300mg in pregnant women. Animal studies have not indicated any major hazard during gestation. Therefore, consult your doctor before taking CEFRINE 300MG CAPSULE if you are pregnant or think you may be pregnant.
Breastfeeding
Monitoring requiredIt is not known whether Cefdinir may pass breast milk. Therefore, CEFRINE 300MG CAPSULE should be used in breastfeeding women only if considered necessary by the physician.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy machines or tools if your ability is affected by CEFRINE 300MG CAPSULE.
Kidney
Use with CautionCEFRINE 300MG CAPSULE should be used with caution in patients with kidney problems. Therefore, consult your doctor for advice before taking it.
Allergy
ContraindicatedDo not take CEFRINE 300MG CAPSULE if you are allergic to Cefdinir, penicillins or any other medicines of cephalosporin drug class.
Use In Pediatrics
Consult your doctorThe safety and effectiveness of Cefdinir have not been established in children. Therefore, consult your doctor before administering CEFRINE 300MG CAPSULE in children.
Use In Geriatrics
Use with CautionCEFRINE 300MG CAPSULE should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
Others
Before taking CEFRINE 300MG CAPSULE, inform your doctor if you:
- Previously experienced diarrhea upon taking any antibiotics
- Are suffering from ulcerative colitis
Interactions
A. Drug-Drug Interactions:
- Antacids (such as aluminium hydroxide, magnesium hydroxide)
- Probenecid (used for gout management)
- Iron supplements
Overdosage:
If you or anyone else accidentally took too many doses of CEFRINE 300MG CAPSULE, consult your doctor for advice immediately. Symptoms of overdosage might include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Synopsis
| Drug | : | Cefdinir |
| Pharmacological Category | : | Third generation Cephalosporin |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Dry Syrup |
More Information
Storage
- Keep CEFRINE 300MG CAPSULE out of reach of children
- Store CEFRINE 300MG CAPSULE at room temperature
FAQs About CEFRINE 300MG CAPSULE
Q: What is CEFRINE 300MG CAPSULE used for?
A: CEFRINE 300MG CAPSULE is used in the management of severe forms of bacterial infections such as Community acquired pneumonia, Acute exacerbation of chronic bronchitis, Uncomplicated skin & skin structure infection, Pharyngitis, tonsillitis and sinusitis and Ear infections (such as Otitis media). It contains Cefdinir which is a third-generation cephalosporin antibiotic. It works by killing the susceptible bacteria that causes infections.
Q: How CEFRINE 300MG CAPSULE works in the body?
A: CEFRINE 300MG CAPSULE contains Cefdinir which is a powerful antibiotic. It works by binding to the bacteria cell wall and inhibiting peptidoglycan synthesis, an essential component in bacterial cells that is required to keep cell wall stronger. This action, causes lysis of bacterial cell wall, disrupting cell components, followed by inactivation of the bacteria cells. Hence, Cefdinir is effective in managing severe bacterial infections.
Q: How to take CEFRINE 300MG CAPSULE?
A: Take CEFRINE 300MG CAPSULE as advised by your physician. It can be taken with or without meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you based on your age, body weight and severity of infection.
Q: Can I stop taking CEFRINE 300MG CAPSULE once I feel better?
A: Follow the dosing schedule as advised by your physician to achieve better results. Do not skip doses or stop taking this medicine without consulting your doctor, even if you feel better, as it could make the medicine less effective against complete eradication of the infections.
Q: Is CEFRINE 300MG CAPSULE safe?
A: CEFRINE 300MG CAPSULE is safe when used under careful medical supervision. It may cause mild diarrhea, nausea, vomiting, stomach upset, headache or dizziness in some individuals. Therefore, consult your doctor for advice if they trouble you.
Q: When can I see an improvement in my condition after taking CEFRINE 300MG CAPSULE?
A: It may take around 1-2 weeks of therapy to start noticing improvement. However, the therapy duration can take around 1 month or more based on the severity of infection.
Q: Can CEFRINE 300MG CAPSULE be used during pregnancy?
A: There are no adequate results regarding the use of Cefdinir 300mg in pregnant women. Animal studies have not indicated any major hazard during gestation. Therefore, consult your doctor before taking CEFRINE 300MG CAPSULE if you are pregnant or think you may be pregnant.
Q: Can CEFRINE 300MG CAPSULE be used in children?
A: The safety and effectiveness of Cefdinir have not been established in children. Therefore, consult your doctor before administering CEFRINE 300MG CAPSULE in children.
Q: Is Cefdinir same as amoxicillin?
A: No, cefdinir and amoxicillin are not the same, though they are both antibiotics. Cefdinir is a third-generation cephalosporin, while amoxicillin is a penicillin-class antibiotic. They work by inhibiting bacterial cell wall synthesis but target different types of bacteria and are used to treat different infections. Cefdinir is generally used for infections that are resistant to first-line antibiotics like amoxicillin, as it has a broader spectrum of activity, particularly against certain Gram-negative bacteria.
Q: What is Cefdinir used for?
A: Cefdinir is used in the management of severe forms of bacterial infections such as Community acquired pneumonia, Acute exacerbation of chronic bronchitis, Uncomplicated skin & skin structure infection, Pharyngitis, tonsillitis and sinusitis and Ear infections (such as Otitis media).
References
1. KD. Tripathi. Essentials of Medical Pharmacology. 8th Edition. Beta-Lactam antibiotics. Page-779.
2. Cefdinir: an advanced-generation, broad-spectrum oral cephalosporin. PubMed. National Library of Medicine. National Center for Biotechnology Information. April 2002. [Accessed on 14th August 2024] https://pubmed.ncbi.nlm.nih.gov/12017394/
3. Torrent Pharmaceuticals Ltd. Cefdinir 300mg Capsules. [Revised in January 2020]. [Accessed on 14th August 2024] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2947.pdf
Useful Diagnostic Tests
- Complete blood count (CBC)
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