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BONAMI CAPSULE contains Calcitriol which belongs to the group of medicines called Vitamin D analogs. It is used to treat and manage bone disorders caused by calcium deficiencies due to various disease conditions such as renal osteodystrophy, menopausal osteoporosis, hyperparathyroidism, hypocalcaemia and hypophosphatemia. Your doctor will monitor your calcium and renal function levels to ensure the efficacy of BONAMI CAPSULE.
Renal osteodystrophy is a complication of chronic kidney disease that weakens bones. It is caused by changes in the levels of minerals and hormones in blood. The main signs are bone pain and fractures. Menopausal osteoporosis is a condition where the bones start weakening in menopausal women. Hyperparathyroidism is a condition when para thyroid hormones secrete excess thyroid hormones. Hypocalcaemia refers to low levels of calcium in blood. Hypophosphatemia indicates low levels of phosphorus in blood.
BONAMI CAPSULE is not recommended for use in patients with high levels of calcium in blood (hypercalcaemia), deposits of calcium (metastatic calcification) and high levels of vitamin D. BONAMI CAPSULE should be used with caution in patients having difficulties in moving due to medical conditions or surgeries and kidney disease. Avoid consuming foods rich in vitamin D. BONAMI CAPSULE should be used with caution in pregnant and breast-feeding women. [GBNKEYWORD should be used with caution in elder patients. The most common side effect of BONAMI CAPSULE is high levels of calcium in blood. Consult your doctor if any side effects worsen or persists for a longer duration.
It is used to treat and manage:
BONAMI CAPSULE acts on cells in the gastrointestinal tract to increase the production of calcium transport proteins (calbindin-D proteins), which results in increased uptake of calcium from the gut into the body. Calcitriol has a direct inhibiting effect on parathyroid hormone synthesis. It inhibits parathyroid hormone activity by decreasing parathyroid hormone synthesis and release. It promotes absorption of dietary calcium from the gastrointestinal tract, increases renal tubular reabsorption of calcium, thus reducing the loss of calcium in the urine, stimulates release of calcium from bone. For this it acts on the specific type of bone cells referred to as osteoblasts. This helps to form healthy bones and reduce bone damage.
Take BONAMI CAPSULE as directed by your physician. Swallow whole medicine with a glass of water. Do not crush or chew. Your doctor will decide the duration depending on your age, body weight and disease condition.
Stop taking BONAMI CAPSULE and contact your doctor if you experience any of the following:
Before taking BONAMI CAPSULE tell your doctor if you are pregnant, think you are pregnant, or plan to get pregnant.
BONAMI CAPSULE is safe for use during breastfeeding. However, your doctor will take blood samples from you and your child to check that there are no unwanted effects.
BONAMI CAPSULE is not likely to affect you being able to drive or use any tools or machines.
BONAMI CAPSULE should be used with caution in patients with kidney disease. Consult your doctor before taking it.
There is no proper information regarding the use of this medicine in patients with liver diseases. Consult your doctor before taking it.
Do not take BONAMI CAPSULE if you are allergic to Calcitriol or any other ingredients of this medicine.
BONAMI CAPSULE should be used with caution in elderly patients aged above 65 years of age. Consult your doctor before taking it.
BONAMI CAPSULE is not recommended for use if you:
Before taking BONAMI CAPSULE inform your doctor if you:
A. Drug-Drug interactions:
Before taking BONAMI CAPSULE, inform your doctor if you are taking any of the following medicine:
B. Drug-Food interactions
Avoid consuming foods rich in vitamin D like milk, cheese as it may increase calcium levels in blood.
If you or anyone else accidentally took more of BONAMI CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms include high levels of calcium in blood signs include loss of appetite, weight loss, nausea, vomiting, headache and inactive, drowsiness.
|Pharmacological Category||:||Vitamin D analogs|
|Therapeutic Indication||:||Renal osteodystrophy, Menopausal osteoporosis, Hyperparathyroidism, Hypocalcaemia, Hypophosphatemia|
Q: Can I take foods rich in calcium along with BONAMI CAPSULE?
A: Avoid consuming foods rich in calcium like milk, cheese as it may increase calcium levels in blood. Do not change your diet with foods rich in Vitamin D. Drink plenty of water to be dehydrated. This does not apply if you have kidney problems.
Q: Can I stop BONAMI CAPSULE once my symptoms subside?
A: No, do not stop taking BONAMI CAPSULE once symptoms get cured bone disease require long term treatment if you stop taking BONAMI CAPSULE it may worsen the existing condition.
Q: What are the uses of BONAMI CAPSULE?
A: BONAMI CAPSULE is used to treat and manage bone disorders caused by calcium deficiencies due to various disease conditions such as renal osteodystrophy, menopausal osteoporosis, hyperparathyroidism, hypocalcaemia and hypophosphatemia.
Q: Can I take double doses to cure my disease?
A: No, do not take additional doses of BONAMI CAPSULE to cure the disease condition as it may cause high levels of calcium in blood. Symptoms include high levels of calcium in blood signs include loss of appetite, weight loss, nausea, vomiting, headache and inactive, drowsiness.
1. KD. Tripathi Drugs affecting calcium balance Essentials of medical pharmacology. Seventh edition. 2013. Page – 341.
2. Lung BE, Mowery ML, Komatsu DEE. Calcitriol November 2021 Stat Pearls NCBI, PMC US National Library of Medicine, National Institute of Health. [Accessed on 9th June 2021] https://www.ncbi.nlm.nih.gov/books/NBK526025/
3. Atnahs Pharma UK Limited Electronic Medicines Compendium (EMC). [Revised in September 2022] [Accessed on 9th June 2021] https://www.medicines.org.uk/emc/files/pil.11802.pdf
4. Catalent Germany Eberbach GmbH Daily med. [Revised in 2019] [Accessed on 9th June 2021] https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=ec93b667-aad2-4e3a-adc6-952f070a0c0a&type=pdf
5. Alniche Calcitriol 0.25mcg Soft gel Capsule. [Accessed on 9th June 2021] https://www.alniche.com/product/auxitrol/
Written By Dr. Janet.C, Pharm.D
Last updated on 18 Mar 2023 | 10:32 PM(IST)
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