INTRODUCTION

BISOCAR 5MG contains Bisoprolol which belongs to group of medicines called beta-blockers. It is used alone to treat high blood pressure and angina pectoris (chest pain caused by blockages in the arteries that supply the heart muscle). This medicine used in combination to treat heart failure. It works by affecting the body’s response to some nerve impulses in the heart and slows down the heart rate and makes the heart more efficient at pumping blood around the body. It is a cardioselective β blocker lacking intrinsic sympathomimetic activity, suitable for angina, hypertension and CHF.

Before taking this medicine, tell your doctor know if you have any liver problems, slow heart rate, severe circulation problems, severe heart failure or low blood pressure. It is not recommended for use in children. The ability to drive or operate machinery may get affected while taking this medicine. Consult your doctor for advice. The most common side effects are tiredness, feeling weak, dizziness, headache, coldness or numbness in hands or feet and low blood pressure.

USES OF BISOCAR 5MG

• Treats high blood pressure and angina pectoris (pain in the chest caused by blockages in the arteries leading to the heart)
• Treats heart failure (in combination)

HOW BISOCAR 5MG WORKS

BISOCAR 5MG by decreasing contractility and the need for oxygen through competitive inhibition of β1-adrenergic receptors, decreases the cardiac workload. It also reduces the renin output in the kidneys, which normally increases blood pressure.

DIRECTIONS FOR USE

Take this medicine according to the dose and frequency as advised by your doctor. Do not chew, crush or break the medicine. It may be taken with or without food.

SIDE EFFECTS OF BISOCAR 5MG

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Constipation:

Eat high rich fiber foods, fruits, vegetables and whole grains.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• medicines used for control blood pressure and heart problems (e.g amiodarone, amlodipine, clonidine, digitalis glycosides, diltiazem, disopyramide, felodipine, flecainide, lidocaine, methyldopa, moxonidine, phenytoin, propafenone, quinidine, rilmenidine, verapamil)
• medicines used to treat depression (e.g. imipramine, amitriptyline, moclobemide)
• medicines to treat any mental illness
• medicines used to treat epilepsy (e.g. phenobarbital)
• pain killers (acetyl salicylic acid, diclofenac, indomethacin, ibuprofen, naproxen)
• medicines for asthma or blocked nose
• medicines used for eye disorders  
• adrenaline, dobutamine, noradrenaline
• mefloquine
• rifampicin (used to treat infections)
• medicines used to treat severe headaches or migraines (ergotamine derivatives)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT BISOCAR 5MG

Is BISOCAR 5MG during pregnancy?

Consult your doctor if you are planning a baby or if you become pregnant before taking this medicine.

Can I stop taking BISOCAR 5MG on my own?

No, you should not stop taking without consulting your doctor as this may worsen your condition.  

Is BISOCAR 5MG recommended for children?

No. This medicine is not recommended for use in children.

REFERENCES

1. KD Tripathi MD. Anti-adrenergic Drugs and Drugs for Glaucoma. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 149-50.

2. Westfall TC & Westfall DP. Adrenergic Agonists and Antagonists. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page -  327- 28.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 441.

4. Neal L. Benowitz, MD. Antihypertensive Agents. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page –221.

5. Terol I, Plaza, L, Rodrigo F. Bisoprolol in the treatment of chronic stable angina pectoris. Journal of Cardiovascular Pharmacology; 1990. [Accessed 29 Oct 2020] https://journals.lww.com/cardiovascularpharm/Abstract/1990/06165/Bisoprolol_in_the_Treatment_of_Chronic_Stable.38.aspx

6. Accord Healthcare Limited; Electronic Medicines Compendium (EMC); [Revised on Feb 2020] [Accessed 29 Oct 2020] https://www.medicines.org.uk/emc/files/pil.6126.pdf

USEFUL DIAGNOSTIC TESTS

• Kidney function test