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INTRODUCTION
BETNESOL N E/E DROPS is a combination of Betamethasone and Neomycin which belongs to the group of medicines called Corticosteroids and Antibiotics respectively. It is used to treat and prevent inflammation and infections of the eyes and ears. It is typically used in conditions which involves inflammation along with the risk of infection such as during injury or post-surgery.
Use this medicine exactly as instructed by your physician. Misuse or overuse of this medicine may lead to unwanted side effects (such as blurred vision or vision impairment). If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice. If you wear soft contact lenses, remove the lens before applying BETNESOL N E/E DROPS and wait for at least 15 minutes before reinsertion.
During treatment with BETNESOL N E/E DROPS, your doctor will regularly monitor your eyes for intraocular pressure, cataracts and for infections as a precaution. Before using BETNESOL N E/E DROPS inform your doctor if you have severe viral or fungal ear/eye infections. You must also inform your doctor if you have glaucoma, perforations (holes) in the ear drum, tuberculosis, dry eyes or damaged skin or wounds around the areas of application.
Do not use BETNESOL N E/E DROPS if you are pregnant or breastfeeding. The most common side effects of using BETNESOL N E/E DROPS are temporary burning sensation and blurring of vision, headache, dizziness, slowing growth and taste changes. Consult your doctor if any of these side effect worsens.
USES OF BETNESOL N E/E DROPS
- Treats eye/ear infection and inflammation
HOW BETNESOL N E/E DROPS WORKS
BETNESOL N E/E DROPS contains two medicines namely, Betamethasone and Neomycin. Betamethasone is a steroid medication. It blocks the release of certain chemicals in the body (such as prostaglandins) that causes inflammation, redness and swelling. When applied topically on the eyes or ears, it reduces redness, soreness, pain, itching and swelling.
Neomycin is an antibiotic. When applied topically on the eyes or ears, it kills the susceptible bacteria that causes infection. Collectively, this medicine reduces inflammation and infection of the eyes and ears.
DIRECTIONS FOR USE
Use BETNESOL N E/E DROPS as advised by your physician. It is for topical use only.
For Eyes: Tilt your head slightly backwards and gently pull your lower eyelid. Instil few drops of this medicine into the eyes and close your eyes for 2 minutes. Repeat the same for the other eye if required. If you wear soft contact lenses, remove the lens before applying BETNESOL N E/E DROPS and wait for at least 15 minutes before reinsertion.
For Ears: Gently instil few drops of this medicine into the affected ear(s).
Wash your hands before and after application. Do not touch the tip of the container with your eyes, eyelids, areas around your eyes, outer ears or using fingers, to avoid contamination.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice.
SIDE EFFECTS OF BETNESOL N E/E DROPS
COMMON
- Burning sensation following application
- Temporary blurring of vision
- Slowing growth
- Breathing difficulties
- Headache, dizziness
- Nausea
- Skin itching
- Changes in taste
- Nose bleeds
RARE
Stop using BETNESOL N E/E DROPS and contact your doctor immediately if you experience any of the following side effects:
- severe eye pain, redness, irritation and vision changes
- blurred vision or other visual disturbances
- abnormal eye sensation, stinging or pain in the eye, swelling and redness around the eyes
- clouding of the eyes (cataracts)
- enlarged pupils, drooping eyelids
- skin irritation, redness and itching
- problems in adrenal gland (causing low blood pressure, dizziness, fever, runny nose, painful itchy skin, eye redness, muscle pain, joint pain and weight loss)
HOW TO MANAGE SIDE EFFECTS
Burning or stinging of eyes:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops or television. Wear protective eyeglasses while going outdoors.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
WARNING & PRECAUTIONS
PREGNANCY
BETNESOL N E/E DROPS is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using it.
BREASTFEEDING
BETNESOL N E/E DROPS is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before using it.
DRIVING AND USING MACHINES
Do not drive or operate any heavy tools or machinery if you experience blurred vision or light-headedness after using BETNESOL N E/E DROPS.
ALLERGY
Do not use BETNESOL N E/E DROPS if you are allergic to Betamethasone or Neomycin.
OTHERS
BETNESOL N E/E DROPS is not recommended for use if you:
- have severe viral eye infections that produces sticky pus
- have severe viral or fungal infections of the ear or nose
- have ulcers in the eyes
- have glaucoma
- wear soft contact lenses
- have a perforated ear drum
Before using BETNESOL N E/E DROPS inform your doctor if you:
- have a mitochondrial disease (a disease that restricts energy supply to the cells)
- have been treated with a steroid medicine recently
- have eye redness for which the cause is unknown
- have tuberculosis infection
- have thinning of tissues surrounding the eyes (such as corneal or scleral thinning)
- have damaged skin or open wounds at the site of application
- have dry eyes or corneal problems
Use in pediatrics:
BETNESOL N E/E DROPS is not recommended for use in children and adolescents (aged below 18 years) unless prescribed by a physician. Therefore, consult your doctor before administration.
Use in geriatrics:
BETNESOL N E/E DROPS should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
INTERACTIONS
A, Drug-Drug interactions:
Before using BETNESOL N E/E DROPS, inform your doctor if you are taking any of the following medicines such as:
- Medicines used to treat HIV infection (such as ritonavir, cobicistat)
Overdosage:
If you or anyone else accidentally used excessive amount of this medicine, rinse your eyes or ears with warm water. If still irritation persists, consult your doctor for advice. If you or anyone else accidentally swallowed this medicine, consult your doctor immediately.
SYNOPSIS
| Drug | : | Betamethasone, Neomycin |
| Pharmacological Category | : | Topical Corticosteroids, Aminoglycoside Antibiotics |
| Therapeutic Indication | : | Eye/Ear inflammation and infection |
| Dosage Forms | : | Cream, Ointment, Eye drops, Ear drops |
MORE INFORMATION
- Keep BETNESOL N E/E DROPS out of reach of children
- Store BETNESOL N E/E DROPS at room temperature
- Do not use this medicine after 4 weeks of its opening, even if it contains some left-over medicine
FAQs ABOUT BETNESOL N E/E DROPS
Q: Can the use of BETNESOL N E/E DROPS cause blurred vision?
A: Yes. BETNESOL N E/E DROPS may cause blurred vision after application in some individuals, although not everybody gets them. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Q: Can I use other eye medicines while using BETNESOL N E/E DROPS?
A: Avoid concomittant use of any eye medicines while using BETNESOL N E/E DROPS without consulting your doctor.
Q: How to use BETNESOL N E/E DROPS?
A: Use BETNESOL N E/E DROPS as advised by your physician. It is for external use only. Instil few drops of this medicine into the affected eyes or ears.
Q: What is the use of BETNESOL N E/E DROPS?
A: BETNESOL N E/E DROPS is a prescription medicine used to treat and prevent inflammation and/or infection of the eyes and ears.
Q: How long does it take for [GBNKRYWORD] to work?
A: It may take around 10-15 minutes for BETNESOL N E/E DROPS to start showing its effects. However, this period may vary from person-to-person depending upon the dose that is administered.
Q: What are the side effects of BETNESOL N E/E DROPS?
A: The most common side effects of using BETNESOL N E/E DROPS are temporary burning sensation and blurring of vision, headache, dizziness, slowing growth and taste changes. Consult your doctor if any of these side effect worsens.
Q: Can I use BETNESOL N E/E DROPS while wearing contact lenses?
A: If you wear soft contact lenses, remove the lens before applying BETNESOL N E/E DROPS and wait for at least 15 minutes before reinsertion.
Q: Can I use BETNESOL N E/E DROPS without consulting my doctor?
A: No. BETNESOL N E/E DROPS is a prescription medicine which should be used only if prescribed by the physician. It is because, BETNESOL N E/E DROPS contains a powerful steroid medicine, which may cause harmful side effects when used without proper medical supervision. Therefore, consult your doctor for advice.
Q: Can I drive or ride a bike after using BETNESOL N E/E DROPS?
A: Do not drive if you experience blurred vision after using BETNESOL N E/E DROPS.
Q: What if I miss a dose of BETNESOL N E/E DROPS?
A: If you missed a dose of BETNESOL N E/E DROPS, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose of BETNESOL N E/E DROPS to compensate the missed dose.
Q: How BETNESOL N E/E DROPS works?
A: BETNESOL N E/E DROPS blocks the release of certain chemicals in the body (such as prostaglandins) that causes pain, inflammation and swelling of the eyes and the ears. It also kills the susceptible bacteria that causes eye/ear infection. Collectively, this medicine reduces inflammation and infection of the eyes and ears.
REFERENCES
1. KD. Tripathi. Hormones and Related Drugs. Aminoglycoside Antibiotics. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 289, 895 & 750.
2. Saeed Shokoohi-Rad, Seyedeh Zeinab Hashemi Javaheri, Fatemeh Zare Malekabad, Hamid Khakshoor, and Mohammad Khajeh Daluee. Effects of preoperative doses of betamethasone acetate 0.1% on dry eye control after cataract surgery. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2020. [Accessed on 5th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043147/
3. M I Bosscha, J T van Dissel, E J Kuijper, W Swart, and M J Jager. The efficacy and safety of topical polymyxin B, neomycin and gramicidin for treatment of presumed bacterial corneal ulceration. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. January 2004. [Accessed on 5th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1771930/
4. RPH Pharmaceuticals AB, Box 603. Electronic Medicines Compendium (EMC). [Revised in January 2021] [Accessed on 5th January 2023] https://www.medicines.org.uk/emc/files/pil.9172.pdf
5. Betamethasone+Neomycin. MIMS.com. [Accessed on 5th January 2023] https://www.mims.com/india/drug/info/betamethasone%20+%20neomycin?type=full&mtype=generic
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