INTRODUCTION

BANDRONE contains Ibandronic acid which belongs to a group of medicines called bisphosphonates. It is used to treat and prevent osteoporosis in women after menopause. It helps to increase bone mass and reduce the chance of having a spinal fracture. Postmenopausal osteoporosis develops after menopause, when estrogen levels drop precipitously. These changes lead to thinning and weakening of the bones which is common in women after the menopause.

It reduces the amount of calcium leaving the bone and make the bone stronger by binding to the bone. It slows down the rate of bone loss and increases the bone density, thus reducing the risk of broken bones and fractures.

This BANDRONE will be administered by a doctor or nurse. Your doctor will decide the dose and frequency depending on your condition. Before receiving this medicine, inform your doctor if you have kidney problems or low calcium levels. It is not recommended for children and adolescents below 18 years of age. The common side effects are diarrhoea, headache, stomach or back pain.

USES OF BANDRONE

• Treats postmenopausal osteoporosis

HOW BANDRONE WORKS

BANDRONE reduces the amount of calcium leaving the bone and make the bone stronger by binding to the bone. It slows down the rate of bone loss and increases the bone density, thus reducing the risk of broken bones and fractures.

DIRECTIONS FOR USE

BANDRONE will be administered by a doctor or nurse. Your doctor will decide the dose and frequency depending on your condition.

SIDE EFFECTS OF BANDRONE

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Heartburn:

Avoid late night eating. Do not exercise right after meals.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking, have recently taken or might take any other medicines with prescription or without prescription such as:

• corticosteroids such as prednisolone and melphalan

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT BANDRONE

How is BANDRONE administered?

It should be administered by a doctor only and should not be self-administered. The dose will depend on the condition as decided by your doctor.

Is BANDRONE safe?

It is safe if used in the dose and duration directed by your doctor.

What is BANDRONE used for?

It belongs to a class of medicines called bisphosphonates that prevents abnormal breakdown of the bones. It is used to treat and prevent osteoporosis in women after menopause

REFERENCES

1. KD Tripathi MD. Drugs affecting calcium balance. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page - 243.

2. Peter A. Friedman. Agents affecting mineral ion Homeostatsis and Bone turnover.  Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 1296.

3. Philip Sambrook. Quarterly intravenous injection of ibandronate to treat osteoporosis in postmenopausal women: Clinical interventions in Aging. March 2007; [Accessed Dec 4, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684081/

4. Accord, Barnstaple, (UK). Synthon Hispania SL. Electronic Medicines Compendium (EMC); [Revised July 2019] [Accessed Dec 4, 2020] https://www.medicines.org.uk/emc/files/pil.4324.pdf

USEFUL DIAGNOSTIC TESTS

• Calcium
• Intact Parathyroid Hormone