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Drug Information

What is Deferasirox used for?

Deferasirox tablet is used for the treatment of excess iron levels in the body and certain blood disorders, such as non-transfusion dependent thalassemia.

Deferasirox may also be prescribed for other conditions as determined by the doctor.

How does Deferasirox work?

Deferasirox belongs to the class of drugs called iron-chelating agents. The drug acts by binding iron with strong affinity and forms a stable complex, thereby facilitating the body to eliminate extra iron through the stool. Thus, it helps in maintaining the blood iron levels.

How to take Deferasirox?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Deferasirox tablet as prescribed by your doctor.

  • Swallow the tablet Do not crush or chew the tablet.
  • Take the drug with or without food. However, taking the drug with food prevents stomach upset.

If you miss a dose of Deferasirox, please take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

The overdose symptoms of Deferasirox include the following:

  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Lack of energy
  • Flu-like symptoms
  • Yellowing of the skin or eyes
  • Unusual bruising or bleeding

Please seek immediate medical attention if you experience any of the above symptoms.

What are the drugs that interact with Deferasirox?

Drugs that interact with Deferasirox include the following:

  • Acetaminophen
  • Clopidogrel
  • Codeine
  • Cyclosporine
  • Dabigatran
  • Dextromethorphan
  • Guaifenesin
  • Ibuprofen
  • Lidocaine
  • Naproxen
  • Omeprazole
  • Oxycodone
  • Salicylamide
  • Warfarin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Deferasirox?

The following are the most common side effects of Deferasirox:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Voice changes
  • Earache

The following are the severe side effects and you may require immediate medical attention:

  • Pale skin
  • Unusual tiredness
  • Fever
  • Chills
  • Persistent sore throat
  • Persistent abdominal pain
  • Bruising or bleeding
  • Black or bloody stools

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Deferasirox?

  • Avoid taking the medicine if you are allergic to Deferasirox or similar drugs.
  • Seek doctor’s advice before taking any other drug or herbal products while on
  • Avoid taking Deferasirox medication while having stomach or intestinal ulcers.
  • Avoid consumption of alcohol as it may alter the absorption of Deferasirox.
  • Do not drive or operate heavy machinery if Deferasirox causes dizziness or blurred vision.
  • Be cautious while using Deferasirox medication in geriatric patients.

You are advised not to take Deferasirox if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Deferasirox?

  • Tell your doctor if you have any history of liver, kidney disease, advanced stage of cancer or a bone marrow disorder.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Notify your doctor if you get pregnant while taking Deferasirox.

Frequently Asked Questions about Deferasirox

  1. Is it safe to take Deferasirox along with aspirin?
  2. It is not advisable to take Deferasirox medication while using aspirin as it can increase the risk of bleeding.

  3. Is it common to experience decreased urine output and urine discolouration while taking Deferasirox?
  4. Deferasirox can cause harm to the kidneys. Therefore, please consult your doctor immediately if you experience any symptoms, such as decreased urine output and urine discolouration while taking Deferasirox.

  5. Can I take Deferasirox medication if I have decreased levels of platelets in the blood?
  6. Inform your doctor before taking Deferasirox medicine if you have low blood platelet levels.

  7. Is it safe to take Deferasirox medication while receiving steroids?
  8. Inform the doctor while taking Deferasirox medicine along with steroids.

  9. Can I take Deferasirox while taking birth control pills?
  10. Consult your doctor about non-hormonal birth control options while taking Deferasirox medication as it can make the birth control pills less effective. 


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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