INTRODUCTION

ARKAMIN 100MCG contains Clonidine which belongs to a group of medicines called antihypertensives. It is used to lower high blood pressure. High blood pressure is a condition in where the force of the blood against artery walls is high which may lead to many cardiovascular diseases. It is determined both by the amount of blood your heart pumps and the amount of resistance to blood flow in your arteries.

Clonidine stimulates alpha-adrenoreceptors in the brain stem which reduces sympathetic outflow from the central nervous system resulting in decrease in peripheral resistance, renal vascular resistance, heart rate, and blood pressure. It also activates Imidazoline receptors which also causes decreased sympathetic outflow and fall in blood pressure. Before taking this ARKAMIN 100MCG, tell your doctor know if you are suffering from any kidney or liver disease, pregnant or breastfeeding. Take this medicine as instructed by the doctor and should never stop it without consulting the doctor. It is not recommended in children. The common side effects are dizziness, drowsiness and constipation.

USES OF ARKAMIN 100MCG

• Treats hypertension (high blood pressure)

HOW ARKAMIN 100MCG WORKS

ARKAMIN 100MCG works by relaxing blood vessels which makes the heart more efficient at pumping blood around the body.

DIRECTIONS FOR USE

Take this ARKAMIN 100MCG according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. It can be taken with or without food.

SIDE EFFECTS OF ARKAMIN 100MCG

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and drink plenty of fluids. Do not drink too much alcohol.

Drowsiness or dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Feeling sick (nausea) or indigestion:

Stick to simple normal meals and do not eat rich or spicy foods.

Constipation:

Add fruits, vegetables whole grains and other high-fiber foods to your normal diet.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• ibuprofen
• imipramine or mirtazapine
• chlorpromazine
• atenolol
• frusemide
• prazosin, doxazosin
• diazoxide, sodium nitroprusside
• verapamil, diltiazem hydrochloride
• captopril, lisinopril
• digoxin

SYNOPSIS

MORE INFORMATION

Do not store above 30°C and keep out of reach of children.

FAQs ABOUT ARKAMIN 100MCG

Can ARKAMIN 100MCG cause weight gain?

Weight gain is not a common side effect. But, if weight gain worries you, contact your doctor.

How quickly does ARKAMIN 100MCG work?

It starts working relatively rapidly. The patient’s blood pressure declines within 30 to 60 minutes of taking the oral dose, the maximum decrease occurring within 2 to 4 hours.

Can I feel dizzy after taking ARKAMIN 100MCG?

Yes, it can cause dizziness. It may occur when you suddenly get up from lying or sitting position.

REFERENCES

1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page 774-75.

2. Benowitz NL. Antihypertensive Agents. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page 173-74.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page 303-304.

4. Boehringer Ingelheim Limited. Electronic Medicines Compendium (EMC); [Revised on Nov 2018] [Accessed 03, Dec 2020] https://www.medicines.org.uk/emc/files/pil.2200.pdf

5. Boehringer Ingelheim Pharmaceuticals, Inc. U.S. Food & Drug Administration; [Revised on Oct 2009] [Accessed 03, Dec 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/017407s034lbl.pdf

6. Anil Kumar, Souvik Maitra, Puneet Khanna, and Dalim Kumar Baidya. Clonidine for management of chronic pain: A brief review of the current evidences. Jan 2014; [Accessed 03, Dec 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950462/

7. KD Tripathi MD. Antihypertensive drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page - 565.