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ANTIFLU Oral Suspension 75ml
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INTRODUCTION
ANTIFLU ORAL SUSPENSION contains Oseltamivir which belongs to the group of medicines called Antivirals. It is used in adults, adolescents, children and infants (including full-term new-born babies) for the treatment of flu (influenza) and also used as preventive treatment in exceptional circumstances such as if there is a global flu pandemic and the seasonal flu vaccine may not provide sufficient protection.
ANTIFLU ORAL SUSPENSION can be used when you have flu symptoms, and the flu virus is known to be spreading in your community. It can also be used to prevent flu in adults, adolescents, children and infants above 1 year of age, only if you have been in contact with someone affected with flu.
ANTIFLU ORAL SUSPENSION should be taken with caution in patients with kidney problems, long term lung or heart disease. Consult your doctor before taking this medicine.
ANTIFLU ORAL SUSPENSION should be used in pregnant and breastfeeding women only if it is considered clearly necessary. Consult your doctor before taking the medicine.
ANTIFLU ORAL SUSPENSION should be used with caution in children from 1 to 12 years and infants less than 1 year of age. It should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking this medicine.
The most common side effects of taking ANTIFLU ORAL SUSPENSION are headache, nausea, vomiting, stomach ache, stomach upset and pain. Contact your doctor if any of the symptoms get worsen.
USES OF ANTIFLU ORAL SUSPENSION
- Treats flu (influenza) symptoms in adults, adolescents, children and infants (including full-term new-born babies)
- Prevents flu in adults, adolescents, children and infants above 1 year of age
- Used as preventive treatment for adults, adolescents, children and infant (including full-term new-born babies) in a flu pandemic
HOW ANTIFLU ORAL SUSPENSION WORKS
ANTIFLU ORAL SUSPENSION prevents the spread of flu virus inside the body by blocking the action of chemicals required for the survival of virus. This helps to ease or prevent the symptoms of the flu virus infection.
DIRECTIONS FOR USE
Take ANTIFLU ORAL SUSPENSION as advised by your physician. Shake well before use. Take it with food to reduce the chance of nausea and vomiting. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and the severity of infection.
Do not stop using ANTIFLU ORAL SUSPENSION unless your doctor told you to. If you stop using ANTIFLU ORAL SUSPENSION earlier than the doctor told you, the flu symptoms may come back. Always complete the course that your doctor prescribed.
SIDE EFFECTS OF ANTIFLU ORAL SUSPENSION
COMMON
- nausea, vomiting, stomach ache, bloating, stomach upset
- headache
- bronchitis (lung infection)
- signs of cold sore virus (painful, fluid-filled skin blisters)
- cough
- dizziness
- fever
- pain, limb pain
- runny nose
- difficulty in sleeping
- sore throat
- tiredness
- upper respiratory tract infections (infection in nose, throat and sinuses)
- nasal congestion
- conjunctivitis (red eyes and discharge or pain in the eye)
- ear inflammation and other ear disorders
UNCOMMON
- allergic reactions
- change in consciousness
- convulsion (fits)
- heart rhythm abnormalities (fluttering feeling in the chest, chest pain, fainting or dizziness)
- signs of mild to severe liver function disorders
- signs of skin reactions (inflamed, red and itchy rash, scaling skin)
- eardrum disorder
- diarrhea
- diaper rash
RARE
- disturbances in vision
Stop taking ANTIFLU ORAL SUSPENSION and contact your doctor immediately if you experience any of the following side effects:
- anaphylactic and anaphylactoid reactions (severe allergic reactions causing face and skin swelling, itchy rashes and low body pressure and breathing difficulties)
- signs of liver disorders such as fulminant hepatitis, hepatic function disorder and jaundice (yellowing of the skin and eyes, change in stool colour, behavioural changes)
- angioneurotic oedema (sudden onset of severe swelling of the skin mainly around the head and neck area, including eyes and tongue, with breathing difficulties)
- complicated and life life-threatening allergic reaction like Stevens-Johnson syndrome and toxic epidermal necrolysis (severe inflammation of the outer and possibly inner skin, initially with fever, sore throat and fatigue, skin rashes, leading to blisters, peeling, shedding of larger areas of skin, breathing difficulties and low blood pressure)
- signs of gastrointestinal bleeding (prolonged bleeding from the large bowel or spitting up blood)
- signs of neuropsychiatric disorders such as convulsions (fits) and delirium with changed consciousness level, behavioural changes, confusion, delusions (false belief), hallucinations (sensations that feel real but are created by your mind), agitation, anxiety (feeling of fear), nightmares (disturbing dream with negative thoughts) and self-injury
HOW TO MANAGE SIDE EFFECTS
Headache:
Try to rest and relax. Apply pain balm to the head to ease off the pain. Sip on some hot water or ginger tea. If the headache does not improve, contact your doctor.
Nausea or vomiting:
Take this medicine with meals or after meals. Stick to simple meals and avoid eating oil rich or spicy foods. If nausea and vomiting does not improve, contact your doctor.
Stomach pain:
Try to rest and relax. Drink more water and have smaller and frequent meals. Keep a heat pad on your stomach. If the stomach pain does not improve, contact your doctor.
Dizziness:
Sit down or lie down slowly when you are feeling dizziness. Take rest for some time and drink plenty of water. Avoid coffee and other carbonated drinks. If the dizziness does not improve, contact your doctor.
Diarrhoea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Contact your doctor if the diarrhea did not improve.
WARNING & PRECAUTIONS
PREGNANCY
ANTIFLU ORAL SUSPENSION should be used in pregnant women only if it is considered clearly necessary. Consult your doctor before taking the medicine.
BREASTFEEDING
ANTIFLU ORAL SUSPENSION should be used in breastfeeding women only if considered necessary as it may pass through the breast milk. Consult your doctor before taking this medicine.
DRIVING AND USING MACHINES
ANTIFLU ORAL SUSPENSION does not affect your ability to drive or operating machines. Consult your doctor before taking this medicine.
ALCOHOL
Avoid or limit the consumption of alcohol while taking ANTIFLU ORAL SUSPENSION because it might make the medicine less effective.
KIDNEY
ANTIFLU ORAL SUSPENSION should be taken with caution in patients with kidney problems and may need dose adjustment. Consult your doctor before taking this medicine.
LIVER
ANTIFLU ORAL SUSPENSION can be used safely for treatment or for prevention in patients with hepatic dysfunction with no dose adjustment. Consult your doctor before taking it.
ALLERGY
Do not take ANTIFLU ORAL SUSPENSION if you are allergic to oseltamivir or any of the other ingredients of this medicine.
LUNGS
ANTIFLU ORAL SUSPENSION should be taken with caution in patients with long term (chronic) respiratory disease. Consult your doctor before taking this medicine.
HEART DISEASE
ANTIFLU ORAL SUSPENSION should be taken with caution in patients with long term (chronic) heart disease. Consult your doctor before taking this medicine.
OTHERS
Before taking ANTIFLU ORAL SUSPENSION, inform your doctor if:
- you are allergic to other medicines
- you have a severe medical condition that might require immediate hospitalisation
- your immune system which is not working
- you have intolerance to some sugars or hereditary fructose intolerance (HFI)
Use in Pediatrics:
ANTIFLU ORAL SUSPENSION should be used with caution in children from 1 to 12 years and infants less than 1 year.
There is no information on the use of ANTIFLU ORAL SUSPENSION in paediatric patients with hepatic disorder. Consult your doctor before taking this medicine.
Use in geriatrics:
ANTIFLU ORAL SUSPENSION should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking ANTIFLU ORAL SUSPENSION.
INTERACTIONS
A. Drug-Drug interactions:
Before taking ANTIFLU ORAL SUSPENSION, inform your doctor if you are taking any of the following medicine:
- chlorpropamide (medicine used in the treatment of diabetes)
- methotrexate (medicine used to treat rheumatoid arthritis)
- phenylbutazone (medicine used to reduce pain and inflammation)
- probenecid (medicine used in the treatment of gout)
- live attenuated influenza vaccine (used to prevent influenza)
Overdosage:
If you or anyone else accidentally take too much of ANTIFLU ORAL SUSPENSION, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Oseltamivir |
| Pharmacological Category | : | Neuraminidase inhibitors |
| Therapeutic Indication | : | Treatment and prevention of influenza (flu) |
| Dosage Forms | : | Capsule, Oral suspension, Syrup |
MORE INFORMATION
- Keep ANTIFLU ORAL SUSPENSION out of reach of children
- Store below 25°C
FAQs ABOUT ANTIFLU ORAL SUSPENSION
Can I stop ANTIFLU ORAL SUSPENSION after 3days?
It is important to take the medicine exactly as advised by the doctor. ANTIFLU ORAL SUSPENSION is generally prescribed for 5 to 10 days depending on the disease condition. Continue taking this medicine for the full time of treatment even if you begin to feel better after a few days. This will help to clear the infection completely. If you stop taking this medicine too soon, your flu symptoms may return. Consult your doctor before stopping the medicine.
What should I do if forget to take ANTIFLU ORAL SUSPENSION?
If you have missed any dose, take ANTIFLU ORAL SUSPENSION as soon as they remember. It can be avoided if it is near the next scheduled dose (within 2 hours) and then continue to take ANTIFLU ORAL SUSPENSION at the usual times. Do not take a double dose to make up for the forgotten dose.
What are the side effects of taking ANTIFLU ORAL SUSPENSION?
The most common side effects of taking ANTIFLU ORAL SUSPENSION are nausea, vomiting, stomach ache, stomach upset, headache and pain. Usually, they are not severe and mostly occurs in the first 2 days of treatment and will usually stop as treatment continues. Taking this medicine along with food may lessen the chance of getting these side effects. Consult your doctor if any of the side effects bothers you.
Is ANTIFLU ORAL SUSPENSION safe in kidney patients?
ANTIFLU ORAL SUSPENSION when used in patients with renal impairment had higher blood levels of this medicine compared to patients with normal renal function which may increase the risk of ANTIFLU ORAL SUSPENSION associated adverse reactions. Therefore, dosage adjustment is recommended for patients with reduced kidney function. Consult your doctor before taking this medicine.
How do you use ANTIFLU ORAL SUSPENSION?
Take ANTIFLU ORAL SUSPENSION as advised by your physician. Shake well before use. Take it with food to reduce the chance of nausea and vomiting. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and the severity of infection. Do not stop using ANTIFLU ORAL SUSPENSION unless your doctor told you to. If you stop using ANTIFLU ORAL SUSPENSION earlier than the doctor told you, the flu symptoms may come back. Always complete the course that your doctor prescribed.
Can children take ANTIFLU ORAL SUSPENSION?
Yes. ANTIFLU ORAL SUSPENSION should be used with caution in children from 1 to 12 years and infants less than 1 year. Consult your doctor before taking this medicine.
Who should not take ANTIFLU ORAL SUSPENSION?
ANTIFLU ORAL SUSPENSION is not recommended for use in patients with allergic history to oseltamivir or to any of the other ingredients of this medicine. Consult your doctor before taking ANTIFLU ORAL SUSPENSION.
REFERENCES
1. KD. Tripathi. Antiviral drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 802.
2. Oo, Charles, Joanne Barrett, George Hill, Jason Mann, Albert Dorr, Regina Dutkowski and Penny Ward. Pharmacokinetics and dosage recommendations for an oseltamivir oral suspension for the treatment of influenza in children. Paediatric Drugs. August 2012. [Accessed on 12th May 2022] https://link.springer.com/article/10.2165/00128072-200103030-00005
3. McClellan K, Perry CM. Oseltamivir: a review of its use in influenza. NIH, National Library of Medicine, National Center for Biotechnology Information. PubMed.gov. 2001. [Accessed on 12th May 2022] https://pubmed.ncbi.nlm.nih.gov/11270942/
4. Roche Products Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 12th May 2022] https://www.medicines.org.uk/emc/files/pil.9108.pdf
5. Gilead Sciences, Inc. Oseltamivir. [Revised in August 2019] [Accessed on 12th May 2022] https://www.gene.com/download/pdf/tamiflu_prescribing.pdf
6. ANTIFLU Capsules/ Suspension (Oseltamivir phosphate). Ciplamed.com. [Revised in April 2020] [Accessed on 12th May 2022] https://www.ciplamed.com/content/antiflu-capsules-suspension
USEFUL DIAGNOSTIC TESTS
- complete blood count
- viral culture
- rapid antigen testing
- reverse transcription polymerase chain reaction (RT-PCR)
- immunofluorescence assays
- rapid molecular assays
AUTHOR DETAILS
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 10 Jan 2023 | 11:55 AM(IST)
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