Uses of Domperidone+Ranitidine

The combination of Domperidone + Ranitidine is used to treat and prevent:

• Peptic ulcer
• Gastroesophageal reflux disease (GERD; acid reflux)
• Reflux esophagitis (inflammation of food pipe due to acid reflux)
• Zollinger-Ellison syndrome (tumors in pancreas causing the stomach to secrete more acid)
• Nausea and Vomiting
• Acidity, heartburn, indigestion, burping or bloating
• Acid reflux in patients under anaesthesia or labour pain (in pregnant women)

Therapeutic Category

Domperidone: Prokinetic Drugs

Ranitidine: Histamine (H2) receptor blockers

How Domperidone+Ranitidine works

Domperidone stimulates the gut and speeds up the movements of food from the stomach into the intestines. These actions reduce the chances for acid reflux and prevents the irritation of food pipe and other unpleasant symptoms of GI tract (such as acidity, bloating, burping and indigestion).

It also blocks the transmission of nerve signals between the vomiting centres of the spinal cord and the brain which reduces the onset of nausea and vomiting.

Ranitidine blocks the effects of certain chemicals in the gut (such as histamines) that increases stomach acid production. As a result, it heals the existing ulcers and prevents them from becoming worse.

Common side effects of Domperidone+Ranitidine

• Dry mouth
• Constipation
• Low sex drive
• Headache
• Breast pain or tenderness

When to consult your doctor

Consult your doctor if you experience:

• severe stomach pain due to inflammation of pancreas
• fast, slow or irregular heartbeat, difficulty in breathing, feeling faint
• fits
• uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture
• signs of kidney problems (such as low urine output with back pain, painful urination, bloody urine, fever)

Health Tips for Domperidone+Ranitidine

• Domperidone + Ranitidine should be taken at least 15-30 minutes before meals. Follow the dosing schedule as advised by your doctor to achieve better results
• Eat simple meals and avoid spicy foods. Drink plenty of water to keep yourself hydrated
• Regularly visit your doctor and perform all necessary diagnostic tests recommended by your doctor
• Avoid consumption of alcohol while taking Domperidone + Ranitidine, as it could aggravate your existing condition
• Before taking Domperidone + Ranitidine, inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any blockage or tears in the gut as a precaution
• Do not take Domperidone + Ranitidine if you have bleeding from the gut. Consult your doctor before taking Domperidone + Ranitidine if you are pregnant or breastfeeding