VOKEM MF 3 Tablet 10's
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Introduction About VOKEM MF 3 TABLET
VOKEM MF 3 TABLET is indicated as a second-line therapy for the management of type II diabetes mellitus when diet, exercise and therapy with single agents does not result in adequate glycemic control.
It contains a combination of two medicines, namely metformin and voglibose which works together to control blood sugar levels in people with type 2 diabetes. Metformin reduces sugar production in the liver and increases the body’s sensitivity to insulin, helping it use sugar more effectively. Voglibose slows down the breakdown and absorption of carbohydrates in the gut, preventing a sudden rise in blood sugar levels after meals.
Take VOKEM MF 3 TABLET as directed by your physician. Taking this medicine after meals helps to avoid stomach upset. Do not stop using VOKEM MF 3 TABLET without talking to your doctor. Prior to the management, your doctor may want you to take several blood tests to understand your existing kidney condition.
Avoid consumption of alcohol while taking VOKEM MF 3 TABLET as it could aggravate your existing disease condition and increase the risk of lactic acidosis.
VOKEM MF 3 TABLET is generally not recommended for use in pregnant or breastfeeding women and in children (aged less than 18 years) due to lack of safety and effectiveness. It should be used with caution in elderly patients (aged 65 years or above).
The most common side effects of taking VOKEM MF 3 TABLET are nausea, vomiting, diarrhea, stomach pain, headache and dizziness. Consult your doctor if any of the side effects worsen.
Uses Of VOKEM MF 3 TABLET
- To manage type II diabetes mellitus (as second-line of therapy) when diet, exercise and therapy with single agents does not result in adequate glycemic control
How VOKEM MF 3 TABLET Works
[GBNKYWORD] helps to control blood sugar levels, where metformin works by reducing the amount of glucose released into the blood by the liver and voglibose acts by reversibly inhibiting the activity of various carbohydrate digestive enzymes (Ex. sucrose, maltose, zomaltase, etc.) in the gut, thus leading to delayed digestion and absorption of glucose into the blood stream.
How to use VOKEM MF 3 TABLET
- Take VOKEM MF 3 TABLET as advised by your physician.
- It can be taken with or without meals. However, taking this medicine with meals help reduce gastrointestinal discomfort
- Swallow this medicine whole with a glass of water, and do not crush or chew the medicine.
- Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
- Do not stop taking this medicine without consulting your doctor. Otherwise, your blood sugar will rise again.
Side Effects Of VOKEM MF 3 TABLET
Like all medications, this medicine may cause side effects, although they do not occur in everyone.
Common Side Effects of VOKEM MF 3 TABLET:
- nausea, vomiting, diarrhea, stomach pain or loss of appetite
- heart burn
- change in taste
- general weakness
- headache
- dizziness
Stop taking VOKEM MF 3 TABLET and contact your doctor immediately if you experience any of the following side effects:
- symptoms of lactic acidosis (such as vomiting, stomach pain, decreased heartbeat, difficulty in breathing, muscle cramps, general weakness with severe tiredness or reduced body temperature)
- hepatitis (inflammation of liver with tiredness, loss of appetite, weight loss, with or without yellowing of skin or eyes)
- signs of low blood pressure (such as excessive hunger, headache, shaking, sweating, confusion, anxiety, fast heartbeat)
Warning & Precautions
Pregnancy
ContraindicatedVOKEM MF 3 TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Although, available animal and human studies does not indicate any congenital abnormalities, the risk for the growing baby cannot be excluded. If the patient developed gestational diabetes or have a history of diabetes, insulin must be considered as an alternative therapy to be on safer side.
Breastfeeding
Monitoring requiredAnimal studies have indicated that metformin/voglibose may pass through breast milk and can impact the carbohydrate absorption in the nursing offspring. Therefore, breastfeeding women should not take VOKEM MF 3 TABLET unless considered necessary by the physician.
Driving and Using Machines
Use with CautionVOKEM MF 3 TABLET has no direct influence on the ability to drive and use machines, however it may cause hypoglycemia (low blood sugar levels). Patients should be warned about signs of hypoglycemia (such as weakness, dizziness, fast heartbeat, vision disorders or difficulty in concentration) before or while driving or using machines. Do not drive or use any machines if you start to feel these symptoms.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking VOKEM MF 3 TABLET since it may increase the risk of lactic acidosis, dizziness or sleepiness. Consult your doctor before taking VOKEM MF 3 TABLET.
Kidney
ContraindicatedVOKEM MF 3 TABLET is not recommended for use in patients with severe kidney disease. Consult your doctor before taking VOKEM MF 3 TABLET.
Liver
ContraindicatedVOKEM MF 3 TABLET is not recommended for use in patients with liver problems. Consult your doctor before taking VOKEM MF 3 TABLET.
Allergy
ContraindicatedDo not take VOKEM MF 3 TABLET if you are allergic to Metformin or Voglibose.
Heart Disease
ContraindicatedVOKEM MF 3 TABLET is not recommended for use in patients with heart problems (such as recent heart attack or failure, cardiogenic shock (problems in blood circulation) or abnormal breathing). Consult your doctor before taking VOKEM MF 3 TABLET.
Use In Pediatrics
ContraindicatedVOKEM MF 3 TABLET is generally not recommended for use in children and adolescents (under 18 years) due to lack of safety and effectiveness. Consult your doctor before taking VOKEM MF 3 TABLET.
Use In Geriatrics
Use with CautionVOKEM MF 3 TABLET should be used with caution in elderly patients (aged 65 years or above). Management with VOKEM MF 3 TABLET will be usually initiated at the low effective dose depending on kidney, liver or heart function and your doctor may assess the kidney function more frequently. Consult your doctor before taking VOKEM MF 3 TABLET.
Others
VOKEM MF 3 TABLET is not recommended for use if you:
- have lactic acidosis (lactic acid build up in the bloodstream) or ketoacidosis (ketone bodies accumulate in the blood)
- have ever had a diabetic pre-coma
- have severe dehydration (either due to vomiting, diarrhea or shock)
- have severe infection, before and after operation or with serious trauma
- have gastrointestinal obstruction (a block in intestines)
- are alcoholic
Before taking VOKEM MF 3 TABLET, inform your doctor if you:
- have an upcoming major surgery
- are scheduled for X-ray or scan using iodination contrast agents
- have a history of laparotomy or ileus (surgery in abdomen)
- have any chronic intestinal disease (accompanied by disturbed digestion and absorption)
- have aggravating symptoms due to increased generation of intestinal gas (stenosis, large intestine ulcer, severe hernia, roemheld syndrome)
- have vitamin B12 deficiency
- are malnourished
- have problems in pituitary or adrenal glands
Interactions
VOKEM MF 3 TABLET is not recommended for use if you:
- have lactic acidosis (lactic acid build up in the bloodstream) or ketoacidosis (ketone bodies accumulate in the blood)
- have ever had a diabetic pre-coma
- have severe dehydration (either due to vomiting, diarrhea or shock)
- have severe infection, before and after operation or with serious trauma
- have gastrointestinal obstruction (a block in intestines)
- are alcoholic
Before taking VOKEM MF 3 TABLET, inform your doctor if you:
- have an upcoming major surgery
- are scheduled for X-ray or scan using iodination contrast agents
- have a history of laparotomy or ileus (surgery in abdomen)
- have any chronic intestinal disease (accompanied by disturbed digestion and absorption)
- have aggravating symptoms due to increased generation of intestinal gas (stenosis, large intestine ulcer, severe hernia, roemheld syndrome)
- have vitamin B12 deficiency
- are malnourished
- have problems in pituitary or adrenal glands
Synopsis
| Drug | : | Metformin, Voglibose |
| Pharmacological Category | : | Biguanides, Alpha-glucosidase inhibitor |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep VOKEM MF 3 TABLET out of reach of children
- Store at room temperature
FAQs About VOKEM MF 3 TABLET
Q: Can I consume alcohol while taking VOKEM MF 3 TABLET?
A: No, avoid consumption of alcohol while taking VOKEM MF 3 TABLET since it may increase the risk of lactic acidosis, dizziness or sleepiness. Consult your doctor before taking VOKEM MF 3 TABLET if you are alcoholic or having history of alcohol consumption.
Q: Can VOKEM MF 3 TABLET be used in pregnant women?
A: No, VOKEM MF 3 TABLET is not recommended for use in pregnant women. Consult your doctor for advice before taking VOKEM MF 3 TABLET if you are pregnant or planning to get pregnant.
Q: Is VOKEM MF 3 TABLET safe to use in elderly patients?
A: Yes, VOKEM MF 3 TABLET should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking this medicine. Your doctor might check your kidney function frequently to avoid kidney damage and for dose adjustment.
Q: What is VOKEM MF 3 TABLET used for?
A: VOKEM MF 3 TABLET is indicated as a second-line therapy for the management of type II diabetes mellitus when diet, exercise and therapy with single agents does not result in adequate glycemic control.
Q: What to do if I forget to take a dose of VOKEM MF 3 TABLET?
A: You should take VOKEM MF 3 TABLET immediately when you remember. If it is time for your next dose of VOKEM MF 3 TABLET skip the dose and follow your regular dose schedule. Do not double the dose of this medicine to match up your missed dose.
References
1. KD. Tripathi. Insulin, Oral Hypoglycemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 275-276 & 277.
2. Gerald G. Briggs and Roger K. Freeman. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 2451-2456.
3. Takeda. Voglibose Tablets 0.2 / OD Tablets 0.2 Special Drug Use Surveillance "Long-term Use in Patients with Impaired Glucose Tolerance". NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in December 2018]. [Accessed on 9th October 2021] click here
4. Tae Jung Oh, Jae Myung Yu, Kyung Wan Min, Hyun Shik Son, Moon Kyu Lee, Kun Ho Yoon, Young Duk Song, Joong Yeol Park, In Kyung Jeong, Bong Soo Cha, Yong Seong Kim, Sei Hyun Baik, In Joo Kim, Doo Man Kim, Sung Rae Kim, Kwan Woo Lee, Jeong Hyung Park, In Kyu Lee, Tae Sun Park, Sung Hee Choi and Sung Woo Park. Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial. NCBI; PMC US National Library of Medicine, National Institute of Health. June 2019. [Accessed on 9th October 2021] click here
5. Torrent Pharmaceuticals Ltd. Voglitor MF. Torrentian.com. [Revised in July 2020]. [Accessed on 9th October 2021] click here
6. Torrent Pharmaceuticals Ltd. Voglitor MF Forte. Torrentian.com. [Revised in July 2020]. [Accessed on 9th October 2021] click here
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