TORLACTONE 5MG TAB(L)

Introduction About TORLACTONE 5MG TAB(L)

TORLACTONE 5MG TAB(L) is a fixed-dose combination of Spironolactone and Torsemide which belongs to the group of medicines called Diuretics. It is used to reduce fluid accumulation (oedema) in the body that is caused due to severe liver, kidney or heart problems. It can also be used to manage hyperaldosteronism (excessive secretion of aldosterone in the body) and resistant hypertension (high blood pressure that is not controlled by other medicines).

Before taking TORLACTONE 5MG TAB(L) inform your doctor if you have any liver, kidney or heart problems. Avoid consumption of alcohol while taking TORLACTONE 5MG TAB(L) as it may make you feel dizzy or faint even while changing posture.

Avoid consuming potassium rich diet or potassium supplements while taking TORLACTONE 5MG TAB(L), as it may further increase the levels of potassium in your body. TORLACTONE 5MG TAB(L) is not recommended for use in pregnant or breastfeeding women due to increased risk of side effects.

TORLACTONE 5MG TAB(L) may alters the levels of electrolytes in your body and may make you feel dizzy or tired very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and may increase or decrease the dose of this medicine accordingly.

The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, increased urination and impotence. Consult your doctor if any of the side effect bothers you.

Uses Of TORLACTONE 5MG TAB(L)

It is used to manage:

• oedema caused due to severe liver, kidney or heart problems
• hyperaldosteronism (excessive secretion of aldosterone in the body)
• resistant hypertension (high blood pressure that is not controlled by other medicines)

How TORLACTONE 5MG TAB(L) Works

TORLACTONE 5MG TAB(L) contains two medicines namely spironolactone and torsemide. Both spironolactone and torsemide acts by removing the excess water and electrolytes (sodium and chloride) from the body in the form of urine which helps in reducing blood pressure. Additionally, spironolactone can manage the loss of potassium via urine and can block the release of certain chemicals in the kidneys (aldosterone) that causes endocrine problems.

How to use TORLACTONE 5MG TAB(L)

Take TORLACTONE 5MG TAB(L) as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking TORLACTONE 5MG TAB(L) unless your doctor tells you to stop.

Side Effects Of TORLACTONE 5MG TAB(L)

How To Manage Side Effects

Warning & Precautions

Interactions

A. Drug - Drug interactions:

Before taking TORLACTONE 5MG TAB(L), inform your doctor if you are taking any of the following medicines such as:

• cholestyramine (a medicine used to control blood cholesterol levels)
• medicines that exert effects on heart function during emergency conditions (Ex. adrenaline, noradrenaline)
• probenecid (a medicine used to manage gout)
• lithium (a medicine used to manage mental illness)
• medicines used to reduce anxiety and to induce sleep (Ex. phenobarbital) 
• corticosteroids (used to manage inflammation) Ex. methylprednisolone
• adrenocorticotropic hormone (used to manage cortisol deficiency)
• medicines used to relax muscles (Ex. tubocurarine)
• medicines used for pain relief (Ex. indomethacin, aspirin, morphine, fentanyl, codeine)
• cardiac glycosides (used to manage cardiac failure) Ex. digoxin
• carbenoxolone (a medicine used to manage ulcers)
• medicines used to manage bacterial infections Ex. trimethoprim, sulfamethoxazole, ceftriaxone, cefazolin, gentamycin, streptomycin
• cotrimoxazole (a medicine used to manage fungal infections)
• cisplatin (used to manage cancer)
• other potassium-sparing diuretics (used to manage fluid accumulation) Ex. eplerenone
• heparin and low molecular weight heparin (used to manage blood clots)
• potassium supplements (used to manage potassium deficiency) Ex. potassium chloride
• medicines used to manage high blood pressure such as ACE inhibitors, angiotensin II blockers or beta-blockers (Ex. enalapril, telmisartan, valsartan, propranolol)
• medicines used to manage diabetes (Ex. metformin, glimepiride)

B. Drug-Food interactions

Avoid foods rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes such as potassium chloride.

Overdosage:

If you or anyone else accidentally took more TORLACTONE 5MG TAB(L), consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include dehydration,
low blood pressure, decreased body fluids and electrolytes levels, low blood sodium levels, abnormal blood potassium levels, increased RBC count, drowsiness, mental confusion, erythematous rash, nausea, vomiting, dizziness, diarrhoea, or liver problems.

Synopsis

Drug	:	Spironolactone, torsemide
Pharmacological Category	:	Potassium sparing diuretics, Loop diuretics
Therapeutic Indication	:	Oedema, hypertension, Hyperaldosteronism
Dosage Forms	:	Tablet

More Information

• Keep TORLACTONE 5MG TAB(L) out of reach of children
• Store TORLACTONE 5MG TAB(L) at room temperature

FAQs About TORLACTONE 5MG TAB(L)

Q: What is the use of TORLACTONE 5MG TAB(L)?

A: TORLACTONE 5MG TAB(L) is used to reduce fluid accumulation (oedema) in the body that is caused due to severe liver, kidney or heart problems. It can also be used to manage hyperaldosteronism (excessive secretion of aldosterone in the body) and resistant hypertension (high blood pressure that is not controlled by other medicines).

Q: Can I take TORLACTONE 5MG TAB(L) daily?

A: Take TORLACTONE 5MG TAB(L) as advised by your physician. Your doctor will evaluate your health condition and suggests you the number of doses that needs to be taken per day.

Q: What are the possible side effects of TORLACTONE 5MG TAB(L)?

A: The most common side effects of [GBKEYWORD] are headache, dizziness, nausea, vomiting, tiredness, and increased urination. It may also cause impotence in men. Consult your doctor if any of the side effect bothers you. Also inform your doctor immediately if you experience irregular heartbeat, joint pain, muscle pain, extreme dizziness or fainting or rectal bleeding after taking TORLACTONE 5MG TAB(L).

Q: What is the best time to take TORLACTONE 5MG TAB(L)?

A: It is advisable to take TORLACTONE 5MG TAB(L) in the morning preferably after meals. This may avoid frequent urination at the night. However, consult your doctor regarding the time of administration of TORLACTONE 5MG TAB(L).

Q: How long does it take for TORLACTONE 5MG TAB(L) to show the results?

A: It may take a few weeks for TORLACTONE 5MG TAB(L) to show the results, and so take TORLACTONE 5MG TAB(L) regularly as advised by your physician to see the optimum results.

Q: Can TORLACTONE 5MG TAB(L) cause dizziness?

A: Yes, TORLACTONE 5MG TAB(L) may cause dizziness due to the loss of fluids from the body. To avoid this, keep yourself hydrated by drinking plenty of fluids. Avoid driving or operating any tools or machines if you feel dizzy. Consult your doctor if you experience extreme dizziness.

Q: Can I consume alcohol while taking TORLACTONE 5MG TAB(L)?

A: Avoid consumption of alcohol while taking TORLACTONE 5MG TAB(L) as it might make you feel dizzy or faint even when you change posture.

Q: Do I have any food restrictions while taking TORLACTONE 5MG TAB(L)?

A: Avoid food rich in potassium such as bananas, dry fruits, lentils, dairy products, and salt substitutes containing potassium while taking TORLACTONE 5MG TAB(L). It is because TORLACTONE 5MG TAB(L) can reabsorb potassium in the kidneys, and so additionally consumption of potassium rich foods or supplements may further increase the levels of potassium in the blood.

Q: Do we need any laboratory investigations while taking TORLACTONE 5MG TAB(L)?

A: Yes. TORLACTONE 5MG TAB(L) may alter the electrolyte balance in your body, and make you feel tired or dehydrated very easily. To avoid this, your doctor would regularly monitor your serum electrolyte levels and increase or decrease the dose of this medicine accordingly.

Q: Can TORLACTONE 5MG TAB(L) reduce my weight?

A: TORLACTONE 5MG TAB(L) does not have any impact on reducing your weight. But, due to removal of excess water from the body, you may experience a slight reduction in body weight.

Q: Can I take TORLACTONE 5MG TAB(L) to reduce my postpartum belly?

A: No. TORLACTONE 5MG TAB(L) is not indicated for use in postpartum women. Do not take TORLACTONE 5MG TAB(L) unless your doctor has prescribed it. It is not advisable to breastfeed while taking TORLACTONE 5MG TAB(L). Consult your doctor before taking TORLACTONE 5MG TAB(L).

Q: Can TORLACTONE 5MG TAB(L) cause cancer?

A: No. Research does not suggest any risk of cancer while taking [GBNEYWORD]. If you are doubtful consult your doctor for advice.

Q: Can I take TORLACTONE 5MG TAB(L) on my own?

A: No. TORLACTONE 5MG TAB(L) is a prescription medicine. It should be used only when prescribed by a physician. Do not take TORLACTONE 5MG TAB(L) on your own without consulting your doctor.

Q: Can TORLACTONE 5MG TAB(L) affect sense of hearing?

A: Yes, some rare cases of hearing loss have been reported with the use of TORLACTONE 5MG TAB(L). This condition is often reversible after discontinuing the therapy. However, consult your doctor immediately if you experience any disturbances in the sense of hearing.

Q: Can the use of TORLACTONE 5MG TAB(L) cause frequent urination?

A: Yes. TORLACTONE 5MG TAB(L) may cause frequent urination. It tends to excrete the accumulated fluid from the body in the form of urine. As a result, you may experience an increase in tendency to urinate. If this bothers you, contact your doctor.

 Q: Can the use of [GNKEYWORD] make me more tired?

A: Yes. TORLACTONE 5MG TAB(L) may make you feel tired easily because it removes the excess fluids from the body. This reduces your energy levels and make you feel very tired. To avoid this, keep yourself hydrated by drinking plenty of fluids. If you experience extreme tiredness that hinders your daily activities, consult your doctor for advice.

References

1. K.D. Tripathi. Diuretics Essentials of pharmacology seventh edition, 2013 Page no – 581 and 587.

2. Juan Tamargo 1, Julian Segura, Luis M Ruilope. Diuretics in the treatment of hypertension. Part 2: loop diuretics and potassium-sparing agents. NIH. National Library of Medicine. National Centre for biotechnology information. Pubmed.gov. April 2014. [Accessed on 4th February 2023] https://pubmed.ncbi.nlm.nih.gov/24456327/

3. Cipla Ltd. Spironolactone/torsemide. Ciplamed.com. [Revised in April 2015]. [Accessed on 4th February 2023] https://www.ciplamed.com/content/dytor-plus-tablets

4. Torrent Pharmaceuticals Ltd. Spironolactone/torsemide [Revised in July 2016]. [Accessed on 4th February 2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1818.pdf

5. La Renon Healthcare Pvt Ltd. Torvigress Plus. [Accessed on 4th February 2023] https://www.larenon.com/wp-content/uploads/2022/06/Torvigress-Torvigress-Plus-copy.pdf

6. Leeford Healthcare Pvt Ltd. Durite Plus 10. [Accessed on 4th February 2023] https://www.leeford.in/product/648/durite-plus-10

Useful Diagnostic Tests

• Kidney function test

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