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Introduction About PRODEP 20MG SUSPENSION
PRODEP 20MG SUSPENSION contains Fluoxetine which belongs to the group of medicines called Anti-depressants. PRODEP 20MG SUSPENSION is used to manage major depressive episodes, obsessive-compulsive disorder (mental disorder) and bulimia nervosa (eating disorder).
Major depressive disorder is a mental health disorder characterized by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behavior and other physical functions, such as sleep and appetite.
Obsessive-compulsive disorder (OCD) is a mental disorder that is associated with repetitive thoughts (obsessions) and the urge to do things over and again (compulsions).
Bulimia nervosa is a serious eating disorder that is characterized by binge eating followed by methods to avoid being overweight such as vomiting, severe exercise or fasting.
Before taking PRODEP 20MG SUSPENSION, inform your doctor if you have or ever had epilepsy or history of mania, diabetes, liver problems, heart problems and glaucoma.
PRODEP 20MG SUSPENSION is not recommended for use in pregnancy and breastfeeding women as it may harm the unborn baby. Consult your doctor for advice.
The most common side effects of taking PRODEP 20MG SUSPENSION are insomnia, headache, diarrhea, feeling sick (nausea) and fatigue. Contact your physician if any of the above side effects worsen.
Uses Of PRODEP 20MG SUSPENSION
Manage:
- major depressive episodes
- obsessive-compulsive disorder (mental disorder)
- bulimia nervosa (eating disorder)
How PRODEP 20MG SUSPENSION Works
PRODEP 20MG SUSPENSION works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and relieves symptoms of panic and obsessive disorders.
How to use PRODEP 20MG SUSPENSION
Take PRODEP 20MG SUSPENSION as advised by your physician. Shake well before use. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking PRODEP 20MG SUSPENSION without consulting your doctor.
Side Effects Of PRODEP 20MG SUSPENSION
Common
- insomnia
- headache
- diarrhea
- nausea
- not feeling hungry, weight loss
- nervousness, anxiety
- poor concentration
- sexual problems or reduced sex drive
- difficulty in sleep or sleepiness, unusual dreams
- dizziness
- change in taste
- blurred vision
- rapid and irregular heartbeat sensations
- flushing
- yawning
- indigestion, vomiting
- dry mouth
- hives, urticaria, itching
- excessive sweating
- joint pain
- passing urine more frequently
- unexplained vaginal bleeding
- chills
Uncommon
- feeling detached from yourself
- strange thinking
- abnormally high mood
- orgasm problems
- teeth grinding
- muscle twitching
- enlarged (dilated) pupils
- ringing in the ears
- low blood pressure
- shortness of breath
- nose bleeds
- difficulty swallowing
- hair loss
- increased tendency to bruising
- vomiting blood or passing blood in stools
- unexplained bruising or bleeding
- cold sweat
- difficulty passing urine
- feeling hot or cold
- abnormal liver function test results
- feeling general discomfort or illness
Rare
- low salt levels in the blood
- reduced platelets and white blood cells in the blood
- untypical wild behavior
- hallucinations
- difficulty in breathing
- panic attacks
- confusion
- stuttering
- aggression
- vasculitis (inflammation of a blood vessel)
- rapid swelling of the tissues around the neck, mouth, face, and/or throat
- pain in the tube that takes food or water to the stomach
- hepatitis (inflammation of the liver)
- lung problems
- sore throat
- sensitivity to sunlight
- production of breast milk
- severe skin reaction (Steven Johnsons syndrome)
Stop taking PRODEP 20MG SUSPENSION and contact your doctor immediately if you experience any of the following side effects:
- self-harming thoughts
- rash or allergic reaction such as itching, swelling of face, neck, lips, tongue, mouth or throat causing shortness of breath, loss of consciousness and fever or shock
- fits or increase in seizure frequency
- symptoms of serotonin syndrome or neuroleptic malignant syndrome such as fever with faster breathing or heart rate, sweating, muscle stiffness or tremor, confusion, extreme agitation, irritability or sleepiness
- restlessness and cannot sit or stand still (akathisia)
- drowsiness, weakness or confusion (mostly in elderly people)
- prolonged and painful erection
- heart problems, such as fast or irregular heart rate, collapsing, fainting or dizziness upon standing which may indicate abnormal functioning of the heart rate
How To Manage Side Effects
Nausea or Vomiting:
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Contact your doctor if nausea and vomiting do not improve.
Diarrhea:
Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for managing diarrhea. Contact your doctor if it did not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water and electrolytes. Apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if your headache did not improve.
Dizziness or Drowsiness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if your dizziness or drowsiness did not improve.
Warning & Precautions
Pregnancy
PRODEP 20MG SUSPENSION is not recommended for use especially in the last 3 months of pregnancy as it harms the unborn baby. It should be used with caution during late pregnancy or just before giving birth. Consult your doctor before taking PRODEP 20MG SUSPENSION.
Breastfeeding
PRODEP 20MG SUSPENSION will be excreted through breast milk, hence it should be used with caution if it is clearly necessary. Your doctor will lower the dose accordingly. Consult your doctor before taking PRODEP 20MG SUSPENSION.
Driving and Using Machines
Do not drive or operate any machines as it may affect your judgment or coordination after taking PRODEP 20MG SUSPENSION.
Alcohol
Avoid consumption of alcohol while taking PRODEP 20MG SUSPENSION.
Kidney
PRODEP 20MG SUSPENSION should be taken with caution in patients with kidney problems. Consult your doctor before taking PRODEP 20MG SUSPENSION.
Liver
PRODEP 20MG SUSPENSION should be taken with caution in patients with liver problems. Consult your doctor before taking PRODEP 20MG SUSPENSION.
Allergy
Do not take PRODEP 20MG SUSPENSION if you are allergic to Fluoxetine or any of the other ingredients of this medicine.
Lungs
PRODEP 20MG SUSPENSION should be taken with caution in patients with lung problems. Consult your doctor before taking PRODEP 20MG SUSPENSION.
Heart Disease
PRODEP 20MG SUSPENSION should be taken with caution in patients with heart problems or low heart rate. Consult your doctor before taking PRODEP 20MG SUSPENSION.
Others
Before taking PRODEP 20MG SUSPENSION, inform your doctor if you:
- have or ever had epilepsy or fits
- have history of mania
- have diabetes
- have glaucoma
- have ongoing ECT (electroconvulsive therapy)
- have a history of bleeding disorder or blood clotting problems
- have diabetes
- have rare hereditary problems such as fructose intolerance, glucose-galactose malabsorption and sucrase-isomaltase insufficiency
Use in pediatrics:
PRODEP 20MG SUSPENSION is generally not recommended for use in children (under 8 years of age) and should be used with caution in children and adolescents (8 to 18 years of age) for the management of moderate to severe major depression. Consult your doctor before taking PRODEP 20MG SUSPENSION.
Use in geriatrics:
PRODEP 20MG SUSPENSION should be used with caution in elderly patients (above 70 years of age). Consult your doctor before taking PRODEP 20MG SUSPENSION.
Interactions
A. Drug-Drug interactions:
Before taking PRODEP 20MG SUSPENSION, inform your doctor if you are taking any of the following medicine:
- medicine used to manage depression (Ex. tranylcypromine, moclobemide iproniazid, phenelzine, nialamide, isocarboxazid, toloxatone)
- linezolid (used for bacterial infections)
- methylthioninium chloride (used to manage methaemoglobinaemia)
- selegiline (used for parkinson's disease)
- lithium (used to mania)
- L- tryptophan (used to manage premenstrual disorders)
- medicine used to manage epilepsy (Ex. phenytoin, carbamazepine, oxcarbazepine)
- medicine used to manage migraine (Ex. sumatriptan)
- medicine used to manage heart’s rhythm (Ex. Class IA and III antiarrhythmics like quinidine and amiodarone)
- medicine used as antipsychotics (Ex. fluphenazine, pimozide, haloperidol)
- medicine used as antimicrobial agents (Ex. sparfloxacin, moxifloxacin, erythromycin IV, pentamidine)
- medicine used to manage malaria (Ex. halofantrine, mefloquine, chloroquine)
- medicines used to manage allergies (astemizole, mizolastine, mequitazine, cyproheptadine)
- medicine used for heart problems (Ex. flecainide, propafenone or encainide)
- nebivolol (medicines used for high blood pressure)
- atomoxetine (medicines used to manage attention deficit hyperactivity disorder)
- diuretics Ex. chlorothiazide (medicines used to remove sodium and water from the body)
- desmopressin (medicines used to reduce the amount of urine produced by the kidneys)
- medicine used for depression (Ex. tricyclic antidepressants like imipramine, desipramine, amitriptyline, and selective serotonin reuptake inhibitors Ex. citalopram, escitalopram) and or St John’s wort (herbal medicine)
- medicine used to manage breast cancer (Ex. tamoxifen)
- medicine used to thin the blood (Ex. warfarin)
- medicines used to manage pain (Ex. ibuprofen, aspirin, diclofenac, tramadol)
- medicines used to manage certain mental disorders (Ex. clozapine, risperidone)
- metoprolol (medicines used for heart failure)
- buprenorphine/naloxone (medicines used for opioid dependence)
- bupropion (medicines used to stop smoking)
Overdosage:
If you or anyone else accidentally took too much of PRODEP 20MG SUSPENSION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, fits, heart problems (including irregular heartbeat and cardiac arrest) lung problems and change in mental condition ranging from agitation to coma.
Synopsis
| Drug | : | Fluoxetine |
| Pharmacological Category | : | Anti-depressants |
| Therapeutic Indication | : | Major depressive episodes, Obsessive-compulsive disorder, Bulimia nervosa |
| Dosage Forms | : | Tablet, Capsule, Suspension |
More Information
- Keep PRODEP 20MG SUSPENSION out of reach of children
- Store PRODEP 20MG SUSPENSION below 25°C
FAQs About PRODEP 20MG SUSPENSION
What if I take too much PRODEP 20MG SUSPENSION than the prescribed dose?
If you or anyone else accidentally take too much of PRODEP 20MG SUSPENSION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea (feeling sick), vomiting, seizures (fits), heart problems (ranging from irregular heartbeat with no symptoms, heart attack (cardiac arrest), lungs not working properly (pulmonary dysfunction), central nervous system (CNS) alterations (excitation and an altered level of consciousness or loss of consciousness).
What to do if I forget to take PRODEP 20MG SUSPENSION?
You should take PRODEP 20MG SUSPENSION immediately when you remember. If it is time for your next dose skip the dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
Is it safe to drive after taking PRODEP 20MG SUSPENSION?
Do not drive or operate any machines as it may affect your judgment or coordination after taking PRODEP 20MG SUSPENSION. Consult your doctor before taking PRODEP 20MG SUSPENSION.
Is it safe to use PRODEP 20MG SUSPENSION in children?
PRODEP 20MG SUSPENSION is generally not recommended for use in children (under 8 years of age) and should be used with caution in children and adolescents (8 to 18 years of age) for the management of moderate to severe major depression. Consult your doctor before taking PRODEP 20MG SUSPENSION.
What precaution to be taken before taking PRODEP 20MG SUSPENSION?
Before taking PRODEP 20MG SUSPENSION, inform your doctor if you have or ever had epilepsy or fits, mania now or in the past, diabetes, liver problems, heart problems and glaucoma.
Is PRODEP 20MG SUSPENSION addictive?
No, it is not addictive in nature. No habit-forming potential has been seen with its use. Always follow your doctor's advice regarding the duration of its use.
Can I take PRODEP 20MG SUSPENSION with paracetamol?
This medicine can be taken with paracetamol. However, when taken together paracetamol may increase the antidepressant effect of PRODEP 20MG SUSPENSION. Consult your doctor before taking the two medicines as there could be other effects of using the two medicines together.
References
1. James M. O’Donnell, Robert R. Bies, and Richard C. Shelton. Drug Therapy of Depression and Anxiety Disorders, Goodman & Gilman’s: The Pharmacological basics of Therapeutic, 13th Edition. New York McGraw Hill Medical 2018. Page – 267-277.
2. Andrea Rossi, Alessandra Barraco, and Pietro Donda. Fluoxetine: a review on evidence-based medicine. Journal of Annals of General Hospital Psychiatry. February 2004 [Accessed on 13th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC356924/
3. S Alboni, R M van Dijk, S Poggini, G Milior, M Perrotta, T Drenth, N Brunello, D P Wolfer, C Limatola, I Amrein, F Cirulli, L Maggi & I Branchi. Uses of Fluoxetine. Journal of Molecular Psychiatry. November 2015 [Accessed on 13th June 2022] https://www.nature.com/articles/mp2015142
4. Carla Carratala-Ros, Laura Lopez-Cruz, Andrea Martinez-Verdu, Regulo Olivares-Garcia, John D. Salamone and Merce Correa. Impact of Fluoxetine on behaviour. Frontiers in Behavioural Neuroscience. July 2021 [Accessed on 13th June 2022] https://www.frontiersin.org/articles/10.3389/fnbeh.2021.700182/full
6. Pinewood Laboratories Ltd. Electronic Medicines Compendium (EMC). [Revised in November 2020] [Accessed on 23rd June 2022] https://www.medicines.org.uk/emc/files/pil.4564.pdf
7. Kent Pharmaceuticals Limited. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on 23rd June 2022] https://www.medicines.org.uk/emc/files/pil.2122.pdf

