OXYNERVE PLUS Injection 2ml
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Introduction About OXYNERVE PLUS INJECTION
OXYNERVE PLUS INJECTION contains Methylcobalamin, which belongs to the group of medicines called Vitamins. OXYNERVE PLUS INJECTION is used to manage diabetic neuropathy (nerve damage caused by diabetes), peripheral neuropathy (peripheral nerve damage that affects hands, feet, and arms), and megaloblastic anaemia (blood disorder) caused by vitamin B12 deficiency in affected individuals.
OXYNERVE PLUS INJECTION is also used to manage sciatica pain (leg pain), back pain, and general weakness in affected individuals.
OXYNERVE PLUS INJECTION is not recommended for use in patients allergic to mecobalamin and/or other B12-containing medicines.
Before receiving OXYNERVE PLUS INJECTION, inform your doctor if you have Leber's disease (an inherited form of vision loss) and/or are suffering from low potassium levels (with associated signs such as muscle twitches/cramps, low blood pressure), optic nerve disease (swelling and nerve damage to the eyes), and kidney and/or liver problems.
OXYNERVE PLUS INJECTION is not recommended for use during pregnancy and in breastfeeding women. It should be used with caution in children and adolescents (aged 6 months to 18 years) and in elderly patients (aged above 65 years) after consulting the doctor.
The most common side effects of receiving OXYNERVE PLUS INJECTION are headache, nausea, vomiting, diarrhea, loss of appetite, skin rash, and/or hot flushes. Consult your doctor if any of these side effects worsen.
Uses Of OXYNERVE PLUS INJECTION
- Manage diabetic and peripheral neuropathies
- Manage megaloblastic anaemia (caused by vitamin B12 deficiency)
- Manage sciatica pain (leg pain), back pain, and general weakness in affected individuals.
How OXYNERVE PLUS INJECTION Works
OXYNERVE PLUS INJECTION works by aiding in the synthesis of myelin (a lipid-rich material that covers nerve fibers), which helps in protecting the nerve fibers and thereby providing relief from diabetic and peripheral neuropathy, sciatica pain, and back pain in affected individuals. It also promotes nucleic acid synthesis in the bone marrow, which helps in the maturation and division of erythroblasts, thus managing poor production of red blood cells and thereby improving megaloblastic anaemia in affected individuals.
How to use OXYNERVE PLUS INJECTION
OXYNERVE PLUS INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection or into the muscle as an intramuscular injection. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects Of OXYNERVE PLUS INJECTION
Common
- Headache
- Nausea, vomiting, diarrhea, loss of appetite
- Skin rash, hot flushes.
Rare
Stop receiving OXYNERVE PLUS INJECTION and contact your doctor immediately if you experience any of the following side effects:
- Signs of severe allergic reactions such as wheezing, chest tightness, fever, itching, bad cough, blue/grey skin colour, seizures, swelling of the face, lips, tongue, or throat, and/or swelling/pain in the leg or arm.
How To Manage Side Effects
Diarrhea
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.
Headache
If OXYNERVE PLUS INJECTION causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of receiving OXYNERVE PLUS INJECTION. If it lasts more than a week or is severe, inform your doctor.
Nausea And Vomiting
Receive OXYNERVE PLUS INJECTION with or just after a meal. Stick to simple meals. Avoid eating oil-rich or spicy foods, sugary snacks, and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Talk with your doctor if the condition worsens.
Warning & Precautions
Pregnancy
ContraindicatedOXYNERVE PLUS INJECTION is not recommended for use in pregnant women. Consult your doctor before receiving OXYNERVE PLUS INJECTION.
Breastfeeding
ContraindicatedOXYNERVE PLUS INJECTION is not recommended for use in breastfeeding women. Consult your doctor before receiving OXYNERVE PLUS INJECTION.
Kidney
Use with CautionOXYNERVE PLUS INJECTION should be received with caution in patients with kidney problems. Consult your doctor before receiving the medicine.
Liver
Use with CautionOXYNERVE PLUS INJECTION should be received with caution in patients with liver problems. Consult your doctor before receiving the medicine.
Allergy
ContraindicatedDo not receive OXYNERVE PLUS INJECTION if you are allergic to methylcobalamin, other B12-containing medicines, and/or any other ingredients of this medicine.
Use In Pediatrics
Use with CautionOXYNERVE PLUS INJECTION should be used with caution in children and adolescents (aged 6 months to 18 years). Consult your doctor before receiving OXYNERVE PLUS INJECTION.
Use In Geriatrics
Use with CautionOXYNERVE PLUS INJECTION should be used with caution in elderly patients (aged above 65 years). Consult your doctor before receiving the medicine.
Others
Before receiving OXYNERVE PLUS INJECTION, inform your doctor if you:
- Have Leber's disease (an inherited form of vision loss)
- Have signs of a low potassium level in the blood, such as muscle twitches or cramps, low blood pressure, faintness, and/or excessive urination or thirst
- Are suffering from optic nerve disease (swelling and nerve damage to the eyes).
Interactions
A. Drug-drug interactions:
Before receiving OXYNERVE PLUS INJECTION, inform your doctor if you are receiving any of the following medicine:
- Neomycin (used to manage bacterial skin infections)
- Amino salicylic acid (used to manage tuberculosis)
- Histamine H2-antagonists (used to manage recurrence of duodenal ulcers) Ex. ranitidine, famotidine
- Colchicine (used in the management of gout)
- Oral contraceptives (used to manage pregnancy) Ex. ethinyl estradiol and norethindrone
- Chloramphenicol (used to manage bacterial infections)
- Cimetidine (used to manage ulcers of the stomach and intestines)
Overdosage:
OXYNERVE PLUS INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
Synopsis
| Drug | : | Mecobalamin |
| Pharmacological Category | : | Vitamin B12 |
| Therapeutic Indication | : | Diabetic neuropathy, Peripheral neuropathy, Megaloblastic anaemia, General weakness, Sciatica pain, Back pain |
| Dosage Forms | : | Tablet, Oral disintegrating strip, Injection, Nasal spray, Prefilled Syringe |
More Information
Storage
- Keep OXYNERVE PLUS INJECTION out of reach of children
- Store OXYNERVE PLUS INJECTION below 30°C
FAQs About OXYNERVE PLUS INJECTION
Q: What is OXYNERVE PLUS INJECTION used for?
A: OXYNERVE PLUS INJECTION is used to manage diabetic neuropathy (nerve damage caused by diabetes), peripheral neuropathy (peripheral nerve damage that affects hands, feet, and arms), and megaloblastic anaemia (blood disorder) caused by vitamin B12 deficiency. It is also used to manage sciatica pain (leg pain), back pain, and general weakness in affected individuals.
Q: How OXYNERVE PLUS INJECTION is received?
A; OXYNERVE PLUS INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous injection or into the muscle as an intramuscular injection. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q: What are the side effects of OXYNERVE PLUS INJECTION?
A: The most common side effects of receiving OXYNERVE PLUS INJECTION are headache, nausea, vomiting, diarrhea, loss of appetite, skin rash and/or hot flushes. Consult your doctor if any of these side effects worsen.
Q: How OXYNERVE PLUS INJECTION works?
A: OXYNERVE PLUS INJECTION works by aiding in the synthesis of myelin (a lipid-rich material that covers nerve fibers), which helps in protecting the nerve fibers and thereby providing relief from diabetic and peripheral neuropathy, sciatica pain, and back pain in affected individuals. It also promotes nucleic acid synthesis in the bone marrow, which helps in the maturation and division of erythroblasts, thus managing poor production of red blood cells and thereby improving megaloblastic anaemia in affected individuals.
Q: Does OXYNERVE PLUS INJECTION cause headache?
A: Yes, OXYNERVE PLUS INJECTION causes headaches, as it is the commonest side effect associated with the use of OXYNERVE PLUS INJECTION. If such side effects are experienced after receiving the medicine, then try to take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of receiving OXYNERVE PLUS INJECTION. If it lasts more than a week or is severe, then inform your doctor.
Q: Is OXYNERVE PLUS INJECTION safe during pregnancy?
A: OXYNERVE PLUS INJECTION is not recommended for use in pregnant women. Consult your doctor before receiving it.
Q: Who should not use OXYNERVE PLUS INJECTION?
A: Do not receive OXYNERVE PLUS INJECTION if you are allergic to methylcobalamin, other B12-containing medicines, and/or any other ingredients of this medicine.
Q: What precautions must be taken while using OXYNERVE PLUS INJECTION?
A: Before receiving OXYNERVE PLUS INJECTION, inform your doctor if you have Leber's disease (inherited form of vision loss), signs of low potassium level in blood such as muscle twitches/cramps, low blood pressure, faintness, and/or excessive urination/thirst, or are suffering from optic nerve disease (swelling and nerve damage to the eyes), or have kidney problems or liver problems.
Q: Can OXYNERVE PLUS INJECTION be used in children?
A: OXYNERVE PLUS INJECTION should be used with caution in children and adolescents (aged 6 months to 18 years). Consult your doctor before receiving OXYNERVE PLUS INJECTION.
Q: Is OXYNERVE PLUS INJECTION good for nerves?
A: OXYNERVE PLUS INJECTION is a form of vitamin B12 that helps in the production of DNA, RNA, and proteins. It also helps regenerate nerves and aids in the formation of lecithin, which helps repair damaged nerves.
References
1. KD. Tripathi. Drugs affecting blood and blood formation, Vitamins. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 606.
2. Rabia G. Sezer, Abdulkadir Bozaykut, Handan A. Akoglu, and Gül N. Özdemir. The Efficacy of Oral Vitamin B12 Replacement for Nutritional Vitamin B12 Deficiency. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. March 2018. [Accessed on 5th August 2024] https://pubmed.ncbi.nlm.nih.gov/29189512/
3. Emmanuel Andrès, Thomas Vogel, Laure Federici, Jacques Zimmer, Ecaterina Ciobanu, and Georges Kaltenbach. Cobalamin Deficiency in Elderly Patients: A Personal View. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. May 2008. [Accessed on 5th August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672039/
4. Getz Pharma (Pvt) Ltd. Nervon. [Accessed on 5th August 2024] https://getzpharma.com/wp-content/uploads/2016/08/Nervon-Range-Leaflet-Export-GA.pdf
5. Cradle Life Science Pvt. Ltd. MUST Injection. [Accessed on 5th August 2024] https://cradlelifesciences.com/product.php
6. KINESIS BIOCARE. Vitkin-1500 INJECTION. [Accessed on 5th August 2024] https://www.kinesisbiocare.in/vitkin-1500-injection-methylcobalamin-1500mcg-injection--4429240.html
7. KINESIS BIOCARE. Vitkin-1500 INJECTION. [Accessed on 5th August 2024] https://www.kinesisbiocare.in/vitkin-1500-injection-methylcobalamin-1500mcg-injection--4429240.html
8. Integrated Laboratories Pvt Ltd. Methylcobalamin Injection. [Accessed on 5th August 2024] https://integratedlaboratories.in/methylcobalamin-injection-intebion-2500/#
Useful Diagnostic Tests
- Nerve conduction test
- Complete Blood Count (CBC)/ Hemogram
- Vitamin B-12
- Complete Vitamins Profile
- Healthy Midlife Checkup
- Men Health Checkup - Advanced
- Complete Women Checkup
- Women Health Checkup - Essential
- Full Body Checkup – Gold
- Full Body Checkup – Silver
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