ONDNET Tablet 10's

Introduction About ONDNET TABLET

ONDNET TABLET is used to provide relief from sensation of nausea and vomiting. It contains a medicine called Ondansetron which is an anti-emetic medicine. It reduces the nausea and vomiting sensation by blocking the vomiting centres of the brain.

Before taking ONDNET TABLET, inform your doctor if you have severe constipation, heart or liver problems, imbalance with the levels of salts in the blood, such as potassium, sodium and magnesium or if you have been scheduled for any surgery.

Consult your doctor before taking ONDNET TABLET if you are pregnant or breastfeeding.

The dose of ONDNET TABLET will depends on the age, body weight and disease condition of your child. Dosage adjustment is not required in elderly patients, hence consult your doctor before taking ONDNET TABLET.

The most common side effects of taking ONDNET TABLET includes headache, flushing and constipation. Consult your doctor if any of these above symptoms gets worse.

Uses Of ONDNET TABLET

• Management of nausea and vomiting

How ONDNET TABLET Works

ONDNET TABLET is anti-emetic medicine which works by blocking the action of serotonin, a natural substance in the body that can trigger nausea and vomiting. Specifically, it targets the 5-HT3 receptors in the brain and the gastrointestinal tract. By inhibiting these receptors, ondansetron effectively reduces the signals that lead to nausea and vomiting, providing relief to patients undergoing treatments that can induce these symptoms.

How to use ONDNET TABLET

Take ONDNET TABLET as advised by your physician. It can be taken with or without food.

For Tablet, Capsule: Swallow ONDNET TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.

For Oral Disintegrating strips: Place the medicine directly on your tongue and allow it to dissolve. For fast-dissolving strips, place the strip on your tongue or the inside of your cheek.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.

Side Effects Of ONDNET TABLET

Common Side Effects of ONDNET TABLET:

• headache
• flushing (feeling of warmth)
• constipation
• Dizziness
• Diarrhea

Warning & Precautions

Pregnancy

Consult your doctor

Pregnant women should only use ONDNET TABLET if prescribed by a doctor, after assessing the benefits and risks.

Breastfeeding

Consult your doctor

Limited data is available on the use of ondansetron during breastfeeding. While no harmful effects have been reported in breastfed infants, ondansetron is excreted in breast milk. Therefore, breastfeeding mothers should consult a doctor before using this medicine as a precaution.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy or uneasy after taking ONDNET TABLET.

Liver

Use with Caution

ONDNET TABLET should be used with caution in patients with liver problems. Consult your doctor before taking ONDNET TABLET.

Allergy

Contraindicated

Do not take ONDNET TABLET if you are allergic to ondansetron, granisetron or palonosetron or to any other ingredients of this medicine.

Heart Disease

Use with Caution

ONDNET TABLET should be used with caution in patients with heart diseases such as uneven heartbeats (arrhythmias) or congestive heart failure.

Use In Pediatrics

Monitoring required

ONDNET TABLET can be used in children if prescribed by the physician.

Use In Geriatrics

Monitoring required

ONDNET TABLET can be used in elderly patients if prescribed by the physician.

Interactions

A. Drug-Drug Interactions:

Before taking ONDNET TABLET, inform your doctor, if you are taking any of the following medicine:

• apomorphine (used to manage Parkinson’s disease)
• Antiepileptics (Ex. phenytoin, carbamazepine)
• Anti-TB agent (Ex. rifampicin)
• Pain killers (such as tramadol, methadone)
• Antipsychotic agents (Ex. haloperidol)
• Cardiac agents (Ex. amiodarone) and/or high blood pressure (Ex. atenolol, timolol)
• cancer medicines (Ex. doxorubicin, daunorubicin, monoclonal, trastuzumab) 
• Antibiotics (such as erythromycin, ketoconazole)
• Antidepressants, Sedatives, Anxiolytics (ex. fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine escitalopram)

Overdosage:

If you or anyone else accidentally takes too much of ONDNET TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

FAQs About ONDNET TABLET

Q: Is ONDNET TABLET a chemo drug?

A: No, it is not a chemo drug. It belongs to a group of medicines called serotonin antagonists and used to manage side effects caused due to chemotherapy.

Q: What ONDNET TABLET is used for?

A: ONDNET TABLET is used to manage nausea and vomiting caused by medical managements like chemotherapy, radiotherapy or surgery.

Q: For how long should you take ONDNET TABLET?

A: Your doctor will advise you on how long you should continue to take ONDNET TABLET. Consult your doctor from time to time to review your management and assess your symptoms.

Q: What happens if you take more ONDNET TABLET than your required dose?

A: If you or anyone else accidentally takes too much of ONDNET TABLET, consult your doctor immediately or visit the nearby hospital.

Q: What side effects are seen with ONDNET TABLET?

A: The most common side effects of taking ONDNET TABLET are headaches, flushing (feeling of warmth), constipation. Consult your doctor if above side effects got worse.

References

1. KD. Tripathi. Section 11, Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.

2. LTS Lohmann Therapie-Systeme AG Lohmannstrasse. Andernach GERMANY [Revised April 2022] [Accessed on 29 September 2022] click here

3. Koland M, Sandeep V, Charyulu N. Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation. J Young Pharm. 2010 Jul;2(3):216-22. [Accessed on 29 September 2022] click here

4. Kumria R, Gupta V, Bansal S, Wadhwa J, Nair AB. Oral buccoadhesive films of ondansetron: Development and evaluation. Int J Pharm Investig. 2013 Apr;3(2):112-8. [Accessed on 29 September 2022] click here

5. Ondansetron Soluble Films. [Accessed on 29 September 2022] click here

6. Myoclinic. [Accessed on 29 September 2022] click here

Useful Diagnostic Tests

• Complete blood count

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 11 Feb 2025 | 04:40 PM(IST)