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Introduction About MERISULIDE 50MG SYRUP
MERISULIDE 50MG SYRUP contains Nimesulide which belongs to a group of medicine called Non-steroidal anti-inflammatory drug (NSAID). It is used to manage acute pain, painful osteoarthritis and primary dysmenorrhea.
Your doctor might advise regular liver function tests during management with MERISULIDE 50MG SYRUP. Consult your doctor for advice.
Before taking MERISULIDE 50MG SYRUP tell your doctor if you have ever had kidney disease, heart disease, liver problems. Consult your doctor for advice.
Pregnant and breastfeeding women should consult their doctor before taking MERISULIDE 50MG SYRUP. Consult your doctor for advice.
MERISULIDE 50MG SYRUP is not recommended for use in children and adolescents under 12 years of age. Consult your doctor before taking.
MERISULIDE 50MG SYRUP should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking the medicine.
The most common side effects of MERISULIDE 50MG SYRUP are diarrhoea, nausea, vomiting. Contact your doctor if any of the symptoms worsen or persists for a longer duration.
Uses Of MERISULIDE 50MG SYRUP
It is used to manage:
- acute pain
- painful osteoarthritis
- primary dysmenorrhea
How MERISULIDE 50MG SYRUP Works
MERISULIDE 50MG SYRUP works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
How to use MERISULIDE 50MG SYRUP
Take MERISULIDE 50MG SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of MERISULIDE 50MG SYRUP
Common
- diarrhoea
- nausea
- vomiting
- increase in hepatic enzymes
Uncommon
- dizziness
- hypertension
- dypnoea
- constipation
- flatulence
- gastritis
- pruritus
- rash
- sweating increased
- oedema
Rare
- anaemia
- eosinophilia
- hyperkalaemia
- anxiety
- nervousness
- nightmare
- blurred vision
- tachycardia
- haemorrhage
- blood pressure
- hot flushes
- erythema
- dermatitis
- dysuria
- haematuria
- urinary retention
- malaise
- asthenia
How To Manage Side Effects
Bloating
Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. Consult your doctor if the symptom did not improve.
Constipation
Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Diarrhea
Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Nausea And Vomiting
Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Warning & Precautions
Pregnancy
ContraindicatedMERISULIDE 50MG SYRUP is not recommended for use in pregnant women (especially third trimester of pregnancy). Consult your doctor before taking it.
Breastfeeding
ContraindicatedMERISULIDE 50MG SYRUP is not recommended for use in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizziness or vertigo, somnolence after taking MERISULIDE 50MG SYRUP.
Alcohol
ContraindicatedConsumption of alcohol is not recommended during management with MERISULIDE 50MG SYRUP. Consult your doctor for advice.
Kidney
ContraindicatedMERISULIDE 50MG SYRUP is not recommended in patients with severe renal impairment. Consult your doctor before taking.
Liver
ContraindicatedMERISULIDE 50MG SYRUP is not recommended in patients with liver impairment. Consult your doctor before taking.
Allergy
ContraindicatedDo not take MERISULIDE 50MG SYRUP if you are allergic (hypersensitive) to Nimesulide or any other ingredients of this medicine.
Heart Disease
ContraindicatedMERISULIDE 50MG SYRUP is not recommended in patients with severe heart failure. Consult your doctor before taking.
Others
MERISULIDE 50MG SYRUP is not recommended for use if you:
- have active gastric or duodenal ulcer
- have history of recurrent ulceration or gastrointestinal bleeding
- have cerebrovascular bleeding or other active bleeding or bleeding disorders
- have severe coagulation disorders
Before taking MERISULIDE 50MG SYRUP, inform your doctor if you:
- have gastrointestinal disorders
- have ulcerative colitis, or Crohn's disease
- have bleeding diathesis
Use in Pediatrics:
MERISULIDE 50MG SYRUP is not recommended for use in children and adolescents under 12 years of age. Consult your doctor before taking.
Use in Geriatrics:
MERISULIDE 50MG SYRUP should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before taking this medicine.
Interactions
A. Drug-Drug interactions:
Before taking MERISULIDE 50MG SYRUP, inform your doctor if you are taking any of the following medicine:
- warfarin (used to manage blood clot)
- acetylsalicylic acid
- furosemide
- lithium (used for mental problem)
- glibenclamide, tolbutamide (used to manage diabetes)
- theophylline (used for breathing problems)
- digoxin (used to manage heart problems)
- cimetidine, aluminium hydroxide and magnesium hydroxide (used to manage stomach ulcers)
- methotrexate (used to manage cancer)
- valproic acid (manages epilepsy)
Overdosage:
If you or anyone else accidentally takes too much of MERISULIDE 50MG SYRUP, consult your doctor immediately. Symptoms of overdose are drowsiness, nausea, vomiting, epigastric pain, gastrointestinal bleeding, hypertension.
Synopsis
| Drug | : | Nimesulide |
| Pharmacological Category | : | Non-steroidal anti-inflammatory drug (NSAID) |
| Therapeutic Indication | : | Acute pain, Painful osteoarthritis, Primary dysmenorrhea |
| Dosage Forms | : | Tablet, capsule, Injection, Drops, Oral drops, Gel, Gel(Topical), Suspension, Syrup |
More Information
- Keep out of reach of children
- Store at room temperature
FAQs About MERISULIDE 50MG SYRUP
Q: Is MERISULIDE 50MG SYRUP effective?
A: Yes, it is effective if used in the dose and duration directed by your physician. Consult your doctor if the symptom did not improve.
Q: Can MERISULIDE 50MG SYRUP cause diarrhoea?
A: Yes, this medicine may cause diarrhoea in some individuals. Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhoea. Consult your doctor if the symptom did not improve.
Q: Is MERISULIDE 50MG SYRUP an antibiotic?
A: No, it is not an antibiotic. It belongs to a group of medicine called non-steroidal anti-inflammatory drug (NSAID).
Q: Can I use MERISULIDE 50MG SYRUP during pregnancy?
A: No, MERISULIDE 50MG SYRUP is not recommended for use in pregnant women (especially third trimester of pregnancy). Consult your doctor before taking it.
Q: Can I use MERISULIDE 50MG SYRUP if I have liver disease?
A: No, MERISULIDE 50MG SYRUP is not recommended in patients with liver impairment. Consult your doctor before taking.
References
1. KD Tripathi. Nonsteroidal Anti-inflammatory Drugs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh Edition,2013. Page-203-204.
2. H G Kress 1, A Baltov 2, A Basinski 3, F Berghea 4, J Castellsague 5, C Codreanu 6, E Copaciu 7, M A Giamberardino 8, M Hakl 9, L Hrazdira 10, M Kokavec 11, J Lejcko 12, L Nachtnebl 13, R Stancík 14, A Švec 15, T Tóth 16, M V Vlaskovska 17, J Woron 18. Acute pain: a multifaceted challenge - the role of nimesulide. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 2016. [Accessed on 11 Apr 2022] https://pubmed.ncbi.nlm.nih.gov/26414386/
3. C López Rosales, J H Cisneros Lugo, L J Romo Enciso, M G García Sandoval. [Nimesulide in the treatment of primary dysmenorrhea. Comparative clinical evaluation with mefenamic acid and fentiazac] NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. Jul 1989. [Accessed on 11 Apr 2022] https://pubmed.ncbi.nlm.nih.gov/2486951/
4. Nimesulide. [Accessed on 11 Apr 2022] https://www.ema.europa.eu/en/documents/referral/nimesulide-article-31-referral-annex-iii_en.pdf
Useful Diagnostic Tests
- Complete Blood Count


