Lupactin 2mg Tablet 10'S

Introduction About LUPACTIN 2MG TABLET

LUPACTIN 2MG TABLET contains cyproheptadine, which belongs to the group of medicines called Antihistamines. It is used in the management of allergic conditions in children (aged between 2-7 years), such as seasonal and perineal rhinitis, hay fever, skin rashes and allergic conjunctivitis. The medicine is also used as adjuvant therapy for serious allergic reactions.  

Perennial rhinitis refers to specific allergens that cause an allergic reaction year-round, for example, pet hair or dander, food allergies or medicines. Whereas seasonal allergies typically occur due to changes in the weather or environmental changes that include pollen, insects, moisture, dryness, fungi, mold, etc.

LUPACTIN 2MG TABLET is not recommended for use in premature or newborn infants. This medicine should be used with caution in pregnant women only if recommended by your doctor. It is not recommended for use in breastfeeding mothers. The most common side effects of taking LUPACTIN 2MG TABLET include dizziness, drowsiness, high fever, etc. Contact your doctor if any of the symptoms worsen.

Uses Of LUPACTIN 2MG TABLET

Manages allergic conditions in children (between 2-7 years of age), such as:

• seasonal (occurring during a specific season) and perennial rhinitis (occurring year-round)
• vasomotor rhinitis (reoccurring inflammation of the mucous membrane in the nose)
• allergic conjunctivitis (eye inflammation caused by allergy)
• urticaria (hives) and angioedema (swelling beneath the skin)
• amelioration of allergic reactions to blood or plasma (allergic severe reactions after blood or plasma transfusions)
• cold urticaria (skin reaction to cold)
• dermatographia (a condition causing raised red lines after a scratch)
• It is also used as adjuvant therapy for serious allergic reactions

How LUPACTIN 2MG TABLET Works

LUPACTIN 2MG TABLET manages allergic reactions by binding with certain receptors and blocking them from binding with histamine in the body. Histamine is a mediator found in our body that is responsible for causing allergic symptoms (such as inflammation, itching, irritation, etc.) as a response to allergic conditions. As a result, it provides relief from the allergic condition.

How to use LUPACTIN 2MG TABLET

Take LUPACTIN 2MG TABLET as advised by your physician. Swallow the medicine with a glass of water and it can be taken independent of meals. Do not crush or chew LUPACTIN 2MG TABLET. Your doctor will decide the correct dose, frequency and duration of the management for you depending upon your age, body weight and disease condition.

Side Effects Of LUPACTIN 2MG TABLET

How To Manage Side Effects

Constipation:

Eat plenty of fiber-rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if the symptom does not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom does not improve.

Warning & Precautions

Pregnancy

LUPACTIN 2MG TABLET must be used in pregnant women only if recommended by your doctor. Consult your doctor before taking LUPACTIN 2MG TABLET.

Breastfeeding

LUPACTIN 2MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking LUPACTIN 2MG TABLET.

Driving and Using Machines

Do not drive or operate any machines if you feel dizzy or feel that your mental alertness or motor coordination is affected after taking LUPACTIN 2MG TABLET.

Alcohol

Avoid consumption of alcohol while taking LUPACTIN 2MG TABLET because it causes an additive effect making you feel dizzy or drowsy.

Kidney

LUPACTIN 2MG TABLET should be taken with caution in patients with severe kidney disease. Consult your doctor before taking LUPACTIN 2MG TABLET.

Liver

LUPACTIN 2MG TABLET should be taken with caution in patients with severe liver disease. Consult your doctor before taking LUPACTIN 2MG TABLET.

Allergy

Do not take LUPACTIN 2MG TABLET if you are allergic to cyproheptadine.

Lungs

LUPACTIN 2MG TABLET should be taken with caution in patients with a history of bronchial asthma. Consult your doctor before taking LUPACTIN 2MG TABLET.

Heart Disease

LUPACTIN 2MG TABLET should be taken with caution in patients with cardiovascular disease and hypertension. Consult your doctor before taking LUPACTIN 2MG TABLET.

Interactions

A. Drug-Drug interactions:

Before taking LUPACTIN 2MG TABLET, inform your doctor if you are taking any of the following medicine

• medicines used to manage depression such as MAO inhibitors (Mono Amine Oxidase inhibitors) (Ex. selegiline)
• other depressants such as CNS depressants (Ex. barbiturates)
• medicines used as sedatives (Ex. diazepam)
• medicines used as hypnotics (Ex. zopiclone)
• medicines used as tranquillizers to manage mental disturbances (Ex. alprazolam)
• anti-anxiety medicine used to manage anxiety (Ex. clonazepam)

Overdosage:

If you or anyone else has accidentally taken too much of LUPACTIN 2MG TABLET, consult your doctor immediately or visit the nearby hospital. In the case of an overdose in children, it could cause symptoms such as hallucinations, CNS depression, convulsions and cardiac arrest and can also be fatal, diminishing mental alertness and sometimes causing excitation etc.

Synopsis

More Information

• Keep out of reach from children
• Store at room temperature

FAQs About LUPACTIN 2MG TABLET

Does LUPACTIN 2MG TABLET make you gain weight?

Yes, though LUPACTIN 2MG TABLET is an antihistamine, it is also used to stimulate the appetite and promote weight gain. On the contrary, it is a negative effect as it can cause obesity due to the rapid weight gain in the person after taking it. Consult your doctor before taking LUPACTIN 2MG TABLET.

Can LUPACTIN 2MG TABLET be used for insect bites?

Yes, LUPACTIN 2MG TABLET can be used to manage allergic reactions caused by insect bites. Inflammation and irritation caused by the insect bite are restricted by LUPACTIN 2MG TABLET causing relief from symptoms. Consult a doctor before taking LUPACTIN 2MG TABLET.

Can I take LUPACTIN 2MG TABLET with anti-depressants?

No, LUPACTIN 2MG TABLET is not recommended for use with an anti-depressant (Ex. Sertraline, citalopram), as co-administration of these two medicines may increase the risk of having an additive effect on the medicine and can cause unnecessary complications. Consult a doctor for advice before taking LUPACTIN 2MG TABLET.

Does LUPACTIN 2MG TABLET make you feel sleepy?

Yes, LUPACTIN 2MG TABLET has a sedative property that may make you feel sleepy or drowsy. Avoid driving or using heavy machinery while taking LUPACTIN 2MG TABLET.

How long should I take LUPACTIN 2MG TABLET?

LUPACTIN 2MG TABLET should be taken for as long as your doctor has prescribed it. However, consult your doctor immediately if you experience any of the side effects and they persist or worsen with rash, fever or weight gain.

Who should avoid taking LUPACTIN 2MG TABLET?

Avoid taking LUPACTIN 2MG TABLET if you are suffering from bronchial asthma, glaucoma, enlarged prostate, urinary problems or stomach ulcers. Inform your doctor about your medical condition before starting LUPACTIN 2MG TABLET therapy. 

Does LUPACTIN 2MG TABLET cause dry mouth?

Yes, LUPACTIN 2MG TABLET can cause dry mouth. If you experience mouth dryness or feel excessively thirsty, increase your fluid intake, rinse your mouth with water frequently and apply lip balm if you feel your lips are dry or chapped out.

References

1. K D Tripathi. Antiemetics. Essentials of Medical Pharmacology. 8th edition. Page - 174.

2. Bertrand, Valérie et al. Safety of Cyproheptadine, an Orexigenic Drug. Analysis of the French National Pharmacovigilance Data-Base and Systematic Review. National Library of Medicine. (PMC). September 2021. [Accessed on 18th June 2022]  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525494/

 3. Najib, Khadijehsadat et al. Beneficial effect of cyproheptadine on body mass index in undernourished children: a randomized controlled trial. National Library of Medicine. (PMC). December 2014. [Accessed on 18th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442838/

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7. Ronak Exim Private Limited. [Accessed on 18th June 2022] https://fdaghana.gov.gh/img/smpc/Happyrona%204mg%20Tablets%20(Cyproheptadine).pd

8. Marlex Pharmaceuticals Inc. [Revised in October 2021] [Accessed on 18th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c382a921-f801-4b63-885a-00e71d3c19c7

9. Ciplamed. [Revised in November 2013] [Accessed on 18th June 2022] https://www.ciplamed.com/content/ciplactin-tablets

10. Cadila Healthcare Ltd. Safety Data Sheet. [Accessed on 18th June 2022] https://imgcdn.mckesson.com/CumulusWeb/Click_and_learn/SDS_9ZYDUS_CYPROHEPTADINE_HCL_TAB_4MG_100_BT.pdf

Author Details

Written By Dr. Dhivakaran R - BDS

Reviewed For Accuracy By Dr. Narayanasetty Sai Swaroop - Pharm.D

Last updated on 01 Oct 2022 | 03:48 PM(IST)