Forminal Plus 80mg Tablet 10'S

Introduction About FORMINAL PLUS 80MG TABLET

FORMINAL PLUS 80MG TABLET is a combination of Gliclazide and Metformin hydrochloride, which belongs to the group of medicines called Antidiabetic agents. It is used in the management of diabetes mellitus when dietary measures, physical exercise, and weight loss alone are not sufficient to control blood glucose.

FORMINAL PLUS 80MG TABLET is not recommended for use if you have chronic obstructive pulmonary disease, kidney disease, or liver failure. Consult your doctor before taking it.

FORMINAL PLUS 80MG TABLET is not recommended for use during pregnancy or in breastfeeding women. FORMINAL PLUS 80MG TABLET is not recommended for use in children as safety and effectiveness have not been established. Consult your doctor before taking it.

The most common side effects of taking FORMINAL PLUS 80MG TABLET are nausea, diarrhea, gastric pain, constipation, vomiting, metallic taste in the mouth, rash, pruritus, urticaria, erythema, and flushing. Consult your doctor if any of the side effects worsen.

Uses Of FORMINAL PLUS 80MG TABLET

• To manage type II diabetes mellitus

How FORMINAL PLUS 80MG TABLET Works

FORMINAL PLUS 80MG TABLET effectively controls blood glucose levels, where Gliclazide works by increasing the amount of insulin by stimulating the pancreas and helps control blood glucose levels. Metformin works by decreasing the production of glucose in the liver, decreasing the intestinal absorption of glucose, increasing insulin sensitivity, and allowing better glucose uptake and utilization by the body.

How to use FORMINAL PLUS 80MG TABLET

Take FORMINAL PLUS 80MG TABLET, preferably just before meals, during meals, or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

Side Effects Of FORMINAL PLUS 80MG TABLET

How To Manage Side Effects

Constipation

Include fiber-rich foods in your diet, such as fresh fruits, vegetables, and whole-grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Contact your doctor if constipation persists.

Diarrhea

Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea. Contact your doctor if your diarrhea does not improve.

Nausea And Vomiting

Take FORMINAL PLUS 80MG TABLET with a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting do not improve.

Skin rash Or Itching

Avoid hot baths because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if your rashes worsen.

Stomach Pain

Rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. Do not self-manage on your own, consult your doctor if the symptom does not improve on its own.

Warning & Precautions

Pregnancy

Contraindicated

FORMINAL PLUS 80MG TABLET is not recommended for use during pregnancy. Consult your doctor before taking it.

Breastfeeding

Contraindicated

FORMINAL PLUS 80MG TABLET is not recommended for use by breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

Driving and Using Machines

Use with Caution

Do not drive or operate any machinery if you have increased sweating, a fast heartbeat, vision disorders or difficulty in concentration, dizziness, weakness, or blurred vision after taking FORMINAL PLUS 80MG TABLET.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking FORMINAL PLUS 80MG TABLET, as it may increase the risk of unwanted side effects.

Kidney

Contraindicated

FORMINAL PLUS 80MG TABLET is not recommended for use if you have kidney disease. Consult your doctor before taking it.

Liver

Contraindicated

FORMINAL PLUS 80MG TABLET is not recommended for use if you have liver failure. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take FORMINAL PLUS 80MG TABLET if you are allergic to gliclazide, metformin, or any of the other ingredients of this medicine.

Lungs

Contraindicated

FORMINAL PLUS 80MG TABLET is not recommended for use if you have chronic obstructive pulmonary disease. Consult your doctor before taking it.

Heart Disease

Contraindicated

FORMINAL PLUS 80MG TABLET is not recommended for use if you have coronary heart disease, cardiac failure, or peripheral vascular disease. Consult your doctor before taking it.

Use In Pediatrics

Contraindicated

FORMINAL PLUS 80MG TABLET is not recommended for use in children as safety and effectiveness have not been established. Consult your doctor before taking it.

Use In Geriatrics

Use with Caution

FORMINAL PLUS 80MG TABLET should be used with caution only in elderly patients with normal kidney function. Consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking FORMINAL PLUS 80MG TABLET, inform your doctor if you are taking any of the following medicines, such as:

• angiotensin enzyme inhibitors Ex. captopril, enalapril (medicines used to manage high blood pressure)
• other antidiabetic drugs Ex. insulin, acarbose (medicines used to manage diabetes mellitus)
• beta-blockers Ex. metoprolol (used to manage heart diseases)
• fluconazole (used to manage fungal infections)
• histamine (H) receptor antagonist Ex. cimetidine (used to manage stomach problems)
• monoamine 2 oxidase inhibitors (MAOIs) Ex. selegiline (medicines used to manage depression)
• sulphonamides Ex. sulfasalazine (used to manage gastrointestinal diseases)
• nonsteroidal anti-inflammatory agents Ex. ibuprofen (used to manage pain and inflammation)
• estrogens or oral contraceptives Ex. estradiol, levonorgestrel (used to manage female reproductive health)
• phenytoin (used to manage seizures)
• quinolones Ex. ciprofloxacin (used to manage bacterial infections)

Overdosage:

If you or anyone else accidentally took more FORMINAL PLUS 80MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage may cause low blood sugar (hypoglycemia), and symptoms include dizziness, lightheadedness, hunger, nervousness, shaky feelings, drowsiness, confusion, perspiration, and palpitations. Severe hypoglycemic reactions include fits, neurological disorders, lactic acidosis, and coma.

Synopsis

More Information

• Keep FORMINAL PLUS 80MG TABLET out of the sight and reach of children
• Store FORMINAL PLUS 80MG TABLET below 30°C

FAQs About FORMINAL PLUS 80MG TABLET

References

1. KD. Tripathi. Insulin, Oral Antidiabetic Drugs and Glucagon. Essentials of medical pharmacology. Eight edition. 2019. Page –295.

2. Corcoran C, Jacobs TF. Metformin. NIH National Library of Medicine, National center for biotechnology information. Statpearls. January 2023. [Accessed on 27th December 2023] https://www.ncbi.nlm.nih.gov/books/NBK518983/

3. Panacea Biotec Limited. Gliclazide and metformin. [Revised in September 2014] [Accessed on 27th December 2023] https://media.panaceabiotec.com/documents/2019/7/27/ProductMonograph-GlizidM-GliclazideplusMetformin.pdf

4. Brown & Burk UK Ltd. Electronic Medicines Compendium (EMC) [Revised in May 2022] [Accessed on 27th December 2023] https://www.medicines.org.uk/emc/files/pil.10760.pdf

5. Drug bank. Gliclazide. [Accessed on 27th December 2023] https://go.drugbank.com/drugs/DB01120

6. Drug bank. Metformin. [Accessed on 27th December 2023] https://go.drugbank.com/drugs/DB00331

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Random Blood Sugar (RBS)
• Post Prandial Blood Sugar (PPBS)
• Insulin-Fasting
• Insulin Postprandial (PP)
• Vital Diabetes Care
• Extended Diabetes Care
• Advance Diabetes Care
• Comprehensive Diabetes Care

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)

Last updated on 23 Jan 2024 | 12:05 PM(IST)