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Sanofi India Limited

Enterogermina Suspension 5ml

Diarrhoea
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    Introduction About ENTEROGERMINA SUSPENSION

    Enterogermina Suspension 5ml is a probiotic medicine containing Bacillus clausii spores, formulated to support gut health and restore the natural balance of intestinal bacteria. It is often recommended in cases of digestive disturbances such as diarrhoea, bloating, and indigestion. A common use case is during or after antibiotic therapy, as antibiotics may disrupt gut flora and lead to symptoms like loose stools. By replenishing healthy bacteria, Enterogermina helps maintain a balanced gut environment that supports better digestion and recovery.

    This suspension is suitable for infants, children, and adults, making it a versatile choice across age groups. It may be used in patients experiencing antibiotic-associated diarrhoea, digestive imbalance (dysbiosis), or mild intestinal disturbances due to infections or dietary changes. The liquid format makes it especially convenient for paediatric and elderly patients who may have difficulty swallowing capsules or tablets.

    Enterogermina can be taken before or after meals, usually 2–3 times a day as advised by a doctor. The vial should be shaken well before use and consumed directly or mixed with water. It is important to follow the exact dosage recommended by the healthcare provider. Patients should also observe precautions such as avoiding self-medication for severe diarrhoea, monitoring for allergic reactions, and informing their doctor if they are immunocompromised, critically ill, or on long-term antibiotic therapy.

    In terms of safety, Enterogermina is generally well-tolerated. However, mild side effects such as stomach discomfort, bloating, nausea, or skin rash may occur in some individuals. During pregnancy and breastfeeding, Enterogermina may be used if clearly needed, but only under medical supervision. Patients should seek medical attention if they develop persistent diarrhoea, high fever, severe abdominal pain, allergic reactions, or worsening of symptoms. With proper usage, Enterogermina Suspension 5ml plays a supportive role in maintaining digestive health and faster gut recovery.

    Uses Of ENTEROGERMINA SUSPENSION

    • Used to manage Antibiotic-related diarrhoea
    • Used to manage Gut bacteria imbalance (dysbiosis)
    • Used to manage Bloating and indigestion
    • Used to manage chronic intestinal issues
    • Used to manage Gut health in infants, children, and adults

    Benefits of ENTEROGERMINA SUSPENSION

    Enterogermina for Digestion Support

    Enterogermina Suspension 5ml helps improve digestion by restoring the balance of healthy bacteria in the gut. When digestion is disturbed due to illness, poor diet, or antibiotic use, this probiotic supports better nutrient absorption and reduces discomfort such as bloating or indigestion.

    Enterogermina for Gut Health

    Gut health plays a key role in overall well-being. Enterogermina Suspension 5ml supplies beneficial bacteria (Bacillus clausii) that strengthen the gut environment. A healthy gut flora helps maintain regular bowel movements, improves immunity, and keeps the digestive system functioning smoothly.

    Enterogermina for Loose Stools

    Loose stools are often linked to infection, dietary changes, or antibiotics.  Enterogermina Suspension 5ml helps manage this by restoring natural gut balance and reducing the frequency of watery stools. It also helps prevent weakness and dehydration by promoting quicker recovery of normal bowel function.

    How ENTEROGERMINA SUSPENSION Works

    Enterogermina Mechanism of Action

    Enterogermina Suspension 5ml contains Bacillus clausii spores, a probiotic that survives the acidic environment of the stomach and reaches the intestines alive. Once there, it multiplies and restores the balance of healthy gut bacteria. This helps improve digestion, supports nutrient absorption, and reduces problems such as diarrhoea or indigestion caused by an imbalance in gut flora.

    Enterogermina Activity in Intestine

    Inside the intestine, Enterogermina works by replenishing the natural microflora that may be reduced due to illness, infections, or antibiotics. The beneficial bacteria compete with harmful germs, produce vitamins, and strengthen the intestinal lining. This not only supports normal bowel movements but also helps maintain overall gut health and immunity.

    How to use ENTEROGERMINA SUSPENSION

    Enterogermina How to take

    • Shake the vial well before opening.
    • Twist and break the top to open the vial.
    • Drink the entire contents directly or mix with water/juice.
    • Do not mix with hot drinks or alcohol.
    • Use as advised by your doctor or as mentioned on the pack.

    Enterogermina Dosage

    • Adults: Usually 2–3 vials per day.
    • Children: 1–2 vials per day.
    • Infants: 1 vial per day.
    • Follow your doctor’s instructions for the exact dose.
    • Do not exceed the recommended daily dose.

    Enterogermina Before or After Food

    • Can be taken before or after meals.
    • Taking it after food may reduce stomach discomfort.
    • Maintain regular timing each day for best results.

    What if I forgot to take ENTEROGERMINA SUSPENSION

    • Take the missed dose as soon as you remember.
    • If it’s almost time for your next dose, skip the missed one.
    • Do not double the dose to make up for the missed one.
    • Missing a single dose is usually not harmful, but regular use gives better results.
    • If you often forget, set a reminder or take it at the same time each day.

    Overdose

    Overdosage of Enterogermina suspension is generally well-tolerated and does not produce harmful side effects in healthy individuals. Most people may experience mild digestive discomforts like bloating or gas, which usually resolve on their own. Nevertheless, it is advisable to follow the recommended dosage and avoid excessive intake unless instructed by a doctor. If a large amount is accidentally taken, consult your physician or visit the nearest hospital immediately, especially if persistent symptoms or allergies occur. Special caution is needed for vulnerable groups, such as immunocompromised patients, who should seek medical advice promptly after an overdose.

    Side Effects Of ENTEROGERMINA SUSPENSION

    • Mild stomach discomfort
    • Nausea
    • Bloating or gas
    • Skin rash
    • Taste changes
    • Changes in bowel movements

    When to Seek Medical Attention?

    Stop taking enterogermina suspension 5ml and contact your doctor immediately if you experience any of the following side effects:

    • High fever with digestive problems
    • Severe abdominal pain or cramps
    • Allergic reactions (rash, itching, swelling, breathing difficulty)
    • Infection in immunocompromised patients

    How To Manage Side Effects

    Skin rash Or Itching

    • Cold compress – apply a clean, cool, damp cloth on the rash for 10–15 minutes.
    • Aloe vera gel – use fresh aloe vera gel to soothe redness and itching.
    • Oatmeal bath – soak in lukewarm water mixed with colloidal oatmeal to calm the skin.
    • Coconut oil – apply a thin layer of pure coconut oil to keep the skin moisturized.
    • Avoid scratching – scratching can worsen the rash or cause infection.
    • Loose cotton clothes – wear breathable fabrics to reduce irritation.

    Stomach Discomfort

    • Eat light meals – avoid oily, spicy, or heavy foods.
    • Stay hydrated – drink enough water or oral rehydration solutions.
    • Take Enterogermina after meals to reduce irritation.
    • Use warm compress on the abdomen for relief.
    • Eat slowly and chew well to support digestion.
    • Avoid carbonated drinks and excess caffeine as they may worsen discomfort.
    • Rest and avoid lying down immediately after eating.
    • If stomach discomfort is severe or persistent, consult your doctor.

    Warning & Precautions

    Pregnancy

    Consult your doctor

    Enterogermina suspension 5ml should be used in pregnant women only if considered clearly necessary. Consult your doctor before taking it. 

    Breastfeeding

    Consult your doctor

    Enterogermina suspension 5ml should be used in breast-feeding women only if considered clearly necessary. Consult your doctor before taking it.

    Driving and Using Machines

    Use with Caution

     Enterogermina suspension 5ml has no influence on the ability to drive and use machines.

    Alcohol

    Contraindicated

    Avoid consumption of alcohol while taking Enterogermina Suspension 5ml.

    Kidney

    Use with Caution

    Enterogermina Suspension 5ml should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it. 

    Liver

    Use with Caution

    Enterogermina Suspension 5ml should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

    Allergy

    Contraindicated

    Do not take Enterogermina Suspension 5ml if you are allergic to Bacillus clausii or any of its ingredients.

    Heart Disease

    Use with Caution

    Enterogermina Suspension 5ml should be used with caution in patients with heart problems. Therefore, consult your doctor before taking it.

    Use In Pediatrics

    Safe

    Enterogermina Suspension 5ml is considered safe for children, including infants, but it should always be used under the guidance of a paediatrician.  

    Use In Geriatrics

    Use with Caution

    Enterogermina Suspension 5ml should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.

    Other Warnings for ENTEROGERMINA SUSPENSION

    Before taking Enterogermina Suspension 5ml, inform your doctor if you:

    • have a weakened immune system (such as HIV, cancer, or after an organ transplant)
    • are suffering from bacteraemia, septicaemia, or any severe infection
    • are hospitalized due to a serious medical condition
    • are currently taking antibiotics, as Enterogermina should be taken at least 2 hours apart from them
    • have a history of allergy to probiotics or Bacillus clausii strains

    Safety Advice

    • Do not self-medicate: Always take Enterogermina under medical guidance, especially if symptoms persist for more than a few days.
    • Check expiry date: Do not use the suspension after the expiry date printed on the pack.
    • Do not share: Avoid sharing Enterogermina vials with others, even if they have similar symptoms.
    • Proper administration: Shake the vial well before use to ensure even distribution of the probiotic.
    • Use immediately after opening: Once opened, consume the vial right away; do not store opened vials for later use.
    • Monitor symptoms: If diarrhoea worsens, blood appears in stools, or fever develops, stop use and seek medical advice.
    • Special medical conditions: Inform your doctor if you have recently undergone surgery or have a long-term illness.
    • Combination with supplements: If taking vitamin or mineral supplements, check with your doctor about timing for better absorption.
    • Travel use: Enterogermina can be carried during travel but protect it from direct sunlight and extreme temperatures.

    Diet and Lifestyle Advice

    • Eat light and balanced meals: Choose easily digestible foods like rice, bananas, toast, boiled potatoes, or curd to support gut recovery.
    • Stay hydrated: Drink plenty of water, oral rehydration solutions (ORS), or clear soups to replace fluids lost due to diarrhoea.
    • Avoid oily and spicy food: These can irritate the stomach and worsen digestive problems.
    • Include probiotics naturally: Add foods like yogurt, buttermilk, or fermented foods to help restore gut-friendly bacteria.
    • Limit processed foods: Cut down on packaged snacks, carbonated drinks, and artificial sweeteners, which may upset digestion.
    • Eat small, frequent meals: Instead of heavy meals, take smaller portions throughout the day to ease digestion.
    • Rest well: Give your body enough rest to support natural healing and better digestion.
    • Practice good hygiene: Wash hands thoroughly before eating and after using the restroom to avoid further infections.
    • Avoid smoking: It can disturb digestion and reduce the benefits of probiotics.
    • Exercise moderately: Light walking or stretching can help digestion but avoid heavy workouts during stomach upset.
    • Manage stress: Stress can affect gut health; relaxation techniques like deep breathing or meditation may help.

    1. Enterogermina Suspension 5ml vs. Bifilac Clausi Suspension – Which one is better for gut health

    Feature

    Enterogermina Suspension 5ml

    Bifilac Clausi Suspension

    Composition

    Contains Bacillus clausii spores (a single strain probiotic)

    Contains multiple probiotic strains such as Lactobacillus, Streptococcus, and sometimes Bacillus clausii

    Form

    Ready-to-drink vial (liquid suspension)

    Oral suspension form

    Primary Use

    Helps restore gut flora during/after antibiotic use, supports digestion, and reduces diarrhoea

    Supports overall gut health, reduces diarrhoea, and may improve nutrient absorption due to multi-strain action

    Suitable for

    Infants, children, adults, and elderly (safe across all age groups)

    Commonly prescribed for children and adults; use in infants depends on doctor’s advice

    Tolerance

    Usually, well-tolerated with minimal side effects

    Also, well-tolerated, but multi-strain probiotics may cause mild bloating or gas in some people

    Best Use Case

    When gut imbalance is mainly due to antibiotics or mild digestive upset

    When a broader probiotic support is required for overall digestion and immunity

    Doctor’s Choice

    Preferred for antibiotic-associated diarrhoea and quick gut flora restoration

    Preferred when a multi-strain probiotic approach is needed for better digestion and nutrient absorption

    2. Enterogermina Suspension 5ml be used along with ORS (Oral Rehydration Solution) for faster recovery

    Aspect

    Enterogermina Suspension 5ml

    ORS (Oral Rehydration Solution)

    Together

    Purpose

    Restores healthy gut bacteria and improves digestion

    Replaces lost fluids and electrolytes

    Supports both hydration and gut balance

    Action

    Works on gut flora by introducing beneficial bacteria

    Works on body hydration and electrolyte balance

    Complements each other – gut recovery + hydration

    Use in Diarrhoea

    Helps control and reduce duration of diarrhoea

    Prevents dehydration from fluid loss

    Using both can speed up recovery and prevent complications

    Age Group Suitability

    Safe for infants, children, and adults

    Safe for all age groups

    Safe to use together under medical advice

    Administration

    Taken directly or mixed with water/milk/juice

    Dissolved in clean drinking water and consumed

    Should not be mixed in the same glass – take separately

    Doctor’s Advice

    Recommended when diarrhoea is linked to antibiotic use or gut imbalance

    Essential whenever dehydration risk is present

    Often prescribed together for best results

    3. Enterogermina Suspension 5ml more effective than probiotic capsules

    Aspect

    Enterogermina Suspension 5ml

    Probiotic Capsules

    Form

    Liquid suspension in ready-to-use vials

    Solid capsule form

    Composition

    Contains Bacillus clausii spores (single-strain probiotic)

    Often contains single or multi-strain probiotics depending on brand

    Absorption

    Liquid form is easy to absorb and starts working quickly

    Capsule form may take longer to dissolve and act

    Ease of Use

    Easy for infants, children, and elderly who cannot swallow capsules

    Suitable mainly for adults and older children who can swallow capsules

    Taste/Palatability

    Tasteless, can be mixed with water, milk, or juice

    Neutral capsule but may be difficult for some to swallow

    Storage

    Stable at room temperature; no refrigeration needed

    Some capsule brands may require refrigeration

    Best Use Case

    Preferred for children, infants, elderly, or during antibiotic-associated diarrhoea

    Preferred for adults seeking long-term gut health or multi-strain support

    Drug - Drug interaction

    1. Antibiotics (e.g., amoxicillin, ciprofloxacin, azithromycin) 

    • Interaction: Antibiotics can kill both harmful and beneficial bacteria in the gut, which may reduce the effectiveness of Enterogermina.
    • Management: Maintain a gap of at least 2 hours between taking antibiotics and Enterogermina Suspension to ensure both works effectively.

    2. Immunosuppressants (e.g., corticosteroids, cyclosporine, tacrolimus)

    • Interaction: These medicines weaken the immune system and may increase the risk of infections when using probiotics in vulnerable patients.
    • Management: Use Enterogermina only under strict medical supervision if you are on long-term immunosuppressants.

    3. Antifungal Medicines (e.g., ketoconazole, fluconazole, amphotericin B)

    • Interaction: Some antifungal agents may interfere with the activity of probiotics in the gut.
    • Management: Inform your doctor if you are taking antifungals so they can adjust the timing or evaluate the need for probiotics.

    4. Chemotherapy Medicines

    • Interaction: Certain chemotherapy drugs can affect gut flora and immunity, which may reduce probiotic effectiveness or increase infection risk.
    • Management: Enterogermina should be taken only if advised by your oncologist during chemotherapy treatment.

    5. Other Probiotics or Supplements

    • Interaction: Taking multiple probiotics or gut health supplements at the same time may not cause harm but could lead to redundancy or inconsistent results.
    • Management: Stick to one prescribed probiotic as advised by your doctor to avoid confusion in dosage and effect.

    Drug - Food interaction

    1. Very Hot Food or Drinks

    • Interaction: High temperatures can destroy probiotic bacteria, reducing Enterogermina’s effectiveness.
    • Management: Take Enterogermina with cool or room-temperature liquids. Avoid mixing it with tea, coffee, or hot soup.

    2. Spicy and Oily Foods

    • Interaction: These foods may irritate the stomach and worsen digestive discomfort or diarrhoea.
    • Management: Stick to a light, bland diet while taking Enterogermina for better gut recovery.

    3. High-Sugar Foods and Carbonated Drinks

    • Interaction: Excess sugar and fizzy drinks may promote harmful bacterial growth in the gut and reduce the probiotic’s benefit.
    • Management: Limit sweets, packaged juices, and soft drinks while on Enterogermina. Choose water, coconut water, or ORS instead.

    4. Dairy Products (Milk, Yogurt, Buttermilk)

    • Interaction: Unlike many medicines, Enterogermina is safe with dairy. In fact, dairy may support probiotic survival in the gut.
    • Management: You can safely take Enterogermina with milk or mix it with yogurt or buttermilk if preferred.

    6. Fiber-Rich Foods (Fruits, Vegetables, Whole Grains)

    • Interaction: Dietary fibre acts as “food” for probiotics and helps them multiply in the intestines.
    • Management: Include fruits, vegetables, and whole grains in your diet to enhance the benefits of Enterogermina.

    Synopsis

    Drug

      Enterogermina (Bacillus clausii)

    Pharmacological Category

      Probiotic

    Therapeutic Indication

      Imbalance of gut bacteria, antibiotic-associated diarrhoea, digestive disturbances

    Dosage Forms

      Oral Suspension (vial), Capsule

    More Information

    Storage

    • Store at room temperature (below 30°C).
    • Keep the vials in a cool and dry place, away from direct sunlight and heat.
    • Do not refrigerate or freeze, as extreme temperatures can damage the probiotic bacteria.
    • Keep out of reach of children and pets.

    FAQs About ENTEROGERMINA SUSPENSION

    Q: What is Enterogermina Suspension 5ml used for?

    A: Enterogermina Suspension 5ml is a probiotic medicine that contains beneficial bacteria. It helps restore the balance of good bacteria in your gut, especially when it gets disturbed due to illness, antibiotics, or poor digestion.

    Q: Should Enterogermina be taken before or after meals?

    A: It can usually be taken at any time, but many doctors suggest taking it after meals for better results.

    Q: Does Enterogermina help with antibiotic-related diarrhoea?

    A: Yes, it helps restore healthy gut bacteria that antibiotics often kill, reducing the risk of antibiotic-related diarrhoea.

    Q: How many times a day should I take Enterogermina Suspension?

    A: Usually, 1–2 vials per day are prescribed, but the exact dose depends on your doctor’s advice.

    Q: Can I take Enterogermina on an empty stomach?

    A: Yes, it can be taken on an empty stomach but taking it after food may feel gentler on the stomach.

    Q: Does Enterogermina Suspension have side effects?

    A: Most people do not face side effects. Rarely, mild stomach discomfort, bloating, or gas may occur.

    Q: Does Enterogermina need refrigeration?

    A: No, Enterogermina does not require refrigeration. It should be stored at room temperature away from direct sunlight.

    Q: Can Enterogermina be mixed with milk or juice?

    A: Yes, you can mix it with water, milk, juice, or other liquids for easier intake, especially in children.

    Q: Can Enterogermina be used for constipation?

    A: It mainly supports gut health and loose stools. In some cases, it may help with mild constipation by improving gut balance.

    Q: Can Enterogermina Suspension be taken with food supplements?

    A: Yes, it can be taken with vitamins or minerals but keep a gap if you are also on antibiotics.

    Q: Is Enterogermina available without prescription?

    A: Yes, Enterogermina Suspension 5ml is usually available over the counter, but it is better to use it with medical advice for best results.

    References

    1. KD. Tripathi. Drugs for Constipation and Diarrhoea. Essentials of medical pharmacology. Seventh edition. 2013. Page – 672-688

    2. Princess I, Natarajan T, Ghosh S. When good bacteria behave badly: a case report of Bacillus clausii sepsis in an immunocompetent adult. NIH. National Library of Medicine. National center for biotechnology information. [ Revised in 3rd February 2020]. [Accessed on 20th August 2025]

    3. Ianiro G, Rizzatti G, Plomer M, Lopetuso L, Scaldaferri F, Franceschi F, Cammarota G, Gasbarrini A. Bacillus clausii for the Treatment of Acute Diarrhea in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. NIH. National Library of Medicine. National center for biotechnology information. Pubmed Central.  [Revised in 12th August 2018]. [Accessed on 20th August 2025]

    Author Details

    Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)
    Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS
    Last updated on 26 Aug 2025 | 03:24 PM(IST)
    Lab updated